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Vinylogous Aldol reaction, pyrazole-4,5-diones, allyl ketones, substituted (R,E)-4-hydroxy-4-(4-oxopent-2-en-1-yl)-2,4-dihydro-3H-pyrazol-3-one, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-3,5-bis(trifluoromethyl)-benzamide, Quinine Derivative

Aldol, Vinylogous Aldol

Alkylation, 3‐substituted oxindoles, brominated hydrocarbons, 3,3‐disubstituted oxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine Derivative

Alkylation, Alkylation, alpha-Alkylation

Michael Addition, α,β-unsaturated ketones, substituted 2-cyclohexylidenemalononitrile, substituted 2-(2-(3-oxobutyl)cyclohexylidene)malononitrile, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine Derivative

Michael, Michael Addition

Atropisomer Synthesis, arylalkynes, n-bromosuccinimide, acetyl chloride, Z-vicinal dihaloalkene atropisomers, N-[(8α,9S)-6′-Methoxycinchonan-9-yl]-4-(trifluoromethyl)benzamide, Quinine Derivative

Atropisomer synthesis

Aza-Mannich Addition, oxazolones, N‐protected α‐amido sulfones, substituted 4-(aminomethyl)oxazol-5(4H)-one, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-N′-[(1R)-1-phenylethyl]-thiourea, Quinine Derivative

Aza-Mannich, Mannich

Michael Addition, substituted 3-amino-1H-pyrrole-2,5-dione, 2,6-di-tert-butyl-4-(2-hydroxybenzylidene)cyclohexa-2,5-dien-1-one, substituted (S)-3-amino-4-((3,5-di-tert-butyl-4-hydroxyphenyl)(2-hydroxyphenyl)methyl)-1H-pyrrole-2,5-dione, copper catalyst, 1-((S)-(6-methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methyl)-3-(6-((S)-4-phenyl-4,5-dihydrooxazol-2-yl)pyridin-2-yl)thiourea, Quinine Derivative

Michael, Michael Addition

Dynamic Kinetic Resolution, azlactones, hydrazines, amino acid hydrazides, N-[(8α,9S)-6′-Methoxycinchonan-9-yl]-N′-[4-(trifluoromethyl)phenyl]thiourea, Quinine Derivative

Dynamic Kinetic Resolution, Resolution

Epoxidation, alkylidenemalononitriles, cumene hydroperoxide, 3-substituted oxirane-2,2-dicarbonitrile, N-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]-thiourea, Quinine Derivative

Epoxidation

Aza-Henry (Nitro-Mannich), N-protected pyridin-3-ylmethanimine, nitromethane, N-protected (R)-2-nitro-1-(pyridin-3-yl)ethan-1-amine, immobilized methyl 4-(3-((S)-(6-methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methyl)thioureido)-2-(trifluoromethyl)benzoate, Quinine Derivative

Aza-Henry, Henry, Mannich, Nitro-Mannich

Cycloaddition, ethynyl cyclic carbamates/carbonates, 4-hydroxycoumarins, substituted 2-methylene-2,3-dihydro-4H-furo[3,2-c]pyran-4-one, copper-catalyst, (αS)-N-[(9S)-6′-methoxycinchonan-9-yl]-α-[[2-(diphenylphosphino)benzoyl]amino]-benzenepropanamide, Quinine Derivative

[3+2]-Cycloaddition, Cycloaddition

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