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Michael Addition, (E)-2-(allyloxy)-1-methoxy-3-(2-nitrovinyl)benzene, dimethyl malonate, 7-ring O-heterocycles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine Derivative

Cyclization, Cyclization, Further Cyclizations, Michael, Michael Addition

Thiolation, sulfonyl indoles, triphenylmethanethiol, 3-sec-sulfur-substituted indoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine Derivative

Further reactions, Thiolation

Oxa-Michael, (E)-7-oxo-7-phenylhept-5-enal, methyl (E)-2-oxo-4-phenylbut-3-enoate, pyrano [2,3‐b] pyrans, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine Derivative

Cycloaddition, Diels-Alder reaction, Michael Addition, Oxa-Michael Addition

Aldol reaction, 1-(p-tolyl)ethan-1-one, isatin containing bisphosphonates, indolin containing bisphosphonates, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine Derivative

Aldol, Aldol

Aldol reaction, 5-methoxyindoline-2,3-dione, methyl 3-oxobutanoate, methyl (R)-4-(3-hydroxy-5-methoxy-2-oxoindolin-3-yl)-3-oxobutanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine Derivative

Aldol, Aldol

Spirocyclization, N-benzyl-2-(1H-indol-3-yl)ethan-1-amine, 1-benzylindoline-2,3-dione, (S)-1,2′-dibenzyl-2′,3′,4′,9′-tetrahydrospiro[indoline-3,1′-pyrido[3,4-b]indol]-2-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine Derivative

Spirocyclization

Atropisomer Synthesis, substituted 2-(amino(phenyl)methylene)malonate, brominated hydrocarbons, atropisomers, (9S)-2′-[3,5-bis(1,1-dimethylethyl)phenyl]-9-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-[(3,4,5-trifluorophenyl)methyl]-6′-methoxy-cinchonanium bromide, Quinidine Derivative

Atropisomer synthesis

Cross-Coupling, cyclopropyl halides, terminal alkynes, alkynyl cyclopropanes, copper(II) triflate, N-[(8α,9R)-2′-butyl-6′-methoxycinchonan-9-yl]-1-isoquinolinecarboxamide, Quinidine Derivative

Cross Coupling

Oxa-Michael, α,β-unsaturated carbonyl compound, 1,1‐disubstituted‐1,3‐dihydroisobenzofurans, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine Derivative

intramolecular Oxa-Michael Addition, Michael Addition, Oxa-Michael Addition

Michael Addition, 2‐oxindole‐3‐carboxylate esters, 2‐phthalimido acrylates, substituted 2-oxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Michael, Michael Addition

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