Mannich reaction, methyl 2-oxocyclopentane-1-carboxylate, α‐amido sulfones, substituted 1-(amino(phenyl)methyl)-2-oxocyclopentane-1-carboxylate, (8α,9R)-9-hydroxy-6′-methoxy-1-[(2-methoxyphenyl)methyl]-cinchonanium chloride, Quinine DerivativeMannich, Mannich Desymmetrization, substituted coumarin, cyclohexadienones, substituted 4-((5-oxocyclohex-3-en-1-yl)methyl)-2H-chromen-2-one, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeDesymmetrization Michael Addition, 1-(2-hydroxyphenyl)butane-1,3-dione, (E)-(2-nitrovinyl)benzene, β-nitro chromones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative[3+2] Annulation, Cascade reaction, Cyclization, Further Cyclizations, Michael, Michael Addition Cycloaddition, cyclic nitrones, meldrum’s acid, substituted isoxazolidinone, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-N′-[4-(trifluoromethyl)phenyl]-urea, Quinine Derivative[3+2]-Cycloaddition, Cycloaddition Annulation, enynamides, allyl ketones, 4,5,6,7-tetrahydrofuro [2,3-b] pyridines, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative[4+2] Annulation, Cyclization, Further Cyclizations Atropisomer Synthesis, 3-buten-1-ol, substituted 6-(5H)-phenanthridinon, axially chiral amino acid derivatives, (8α,9R)-1-(9-anthracenylmethyl)-9-hydroxy-6′-methoxy-cinchonanium chloride, Quinine DerivativeAtropisomer synthesis, Further reactions, Ring opening Atropisomer Synthesis, ynamides, thiols, C–N atropisomers, N-[(8α,9S)-6′-Methoxycinchonan-9-yl]-4-(trifluoromethyl)benzamide, Quinine DerivativeAtropisomer synthesis, Michael Addition, Sulfa-Michael, Sulfa-Michael Addition Atropisomer synthesis, tricyclic diazepinones, protected tert-butyl 2-(hydroxymethyl)acrylate, chiral tricyclic diazepinones, Dihydroquinidine BaseAtropisomer synthesis Michael Addition, indolyl ketones, nitromethane, (R)-3-(1H-indol-1-yl)-4-nitro-1-phenylbutan-1-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Dihydroquinidine DerivativeMichael, Michael Addition Atropisomer synthesis, 8‐arylquinolines, halogenating agent, atropisomeric 8‐arylquinolines, N-[3,5-bis(trifluoromethyl)phenyl]-N′- [(9R)-6′-methoxycinchonan-9-yl]-urea, Quinidine DerivativeAtropisomer synthesis, Bromination, Iodination« Older Entries
Mannich reaction, methyl 2-oxocyclopentane-1-carboxylate, α‐amido sulfones, substituted 1-(amino(phenyl)methyl)-2-oxocyclopentane-1-carboxylate, (8α,9R)-9-hydroxy-6′-methoxy-1-[(2-methoxyphenyl)methyl]-cinchonanium chloride, Quinine DerivativeMannich, Mannich
Desymmetrization, substituted coumarin, cyclohexadienones, substituted 4-((5-oxocyclohex-3-en-1-yl)methyl)-2H-chromen-2-one, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeDesymmetrization
Michael Addition, 1-(2-hydroxyphenyl)butane-1,3-dione, (E)-(2-nitrovinyl)benzene, β-nitro chromones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative[3+2] Annulation, Cascade reaction, Cyclization, Further Cyclizations, Michael, Michael Addition
Cycloaddition, cyclic nitrones, meldrum’s acid, substituted isoxazolidinone, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-N′-[4-(trifluoromethyl)phenyl]-urea, Quinine Derivative[3+2]-Cycloaddition, Cycloaddition
Annulation, enynamides, allyl ketones, 4,5,6,7-tetrahydrofuro [2,3-b] pyridines, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative[4+2] Annulation, Cyclization, Further Cyclizations
Atropisomer Synthesis, 3-buten-1-ol, substituted 6-(5H)-phenanthridinon, axially chiral amino acid derivatives, (8α,9R)-1-(9-anthracenylmethyl)-9-hydroxy-6′-methoxy-cinchonanium chloride, Quinine DerivativeAtropisomer synthesis, Further reactions, Ring opening
Atropisomer Synthesis, ynamides, thiols, C–N atropisomers, N-[(8α,9S)-6′-Methoxycinchonan-9-yl]-4-(trifluoromethyl)benzamide, Quinine DerivativeAtropisomer synthesis, Michael Addition, Sulfa-Michael, Sulfa-Michael Addition
Atropisomer synthesis, tricyclic diazepinones, protected tert-butyl 2-(hydroxymethyl)acrylate, chiral tricyclic diazepinones, Dihydroquinidine BaseAtropisomer synthesis
Michael Addition, indolyl ketones, nitromethane, (R)-3-(1H-indol-1-yl)-4-nitro-1-phenylbutan-1-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Dihydroquinidine DerivativeMichael, Michael Addition
Atropisomer synthesis, 8‐arylquinolines, halogenating agent, atropisomeric 8‐arylquinolines, N-[3,5-bis(trifluoromethyl)phenyl]-N′- [(9R)-6′-methoxycinchonan-9-yl]-urea, Quinidine DerivativeAtropisomer synthesis, Bromination, Iodination
