Cascade reaction, 4-(2-(methylthio)ethyl)-2-phenyloxazol-5(4H)-one, (E)-3-(2-hydroxyphenyl)-1-phenylprop-2-en-1-one, 3,4‐dihydrocoumarins, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCascade reaction Carbene Transfer, substituted 3-diazo-4-methylenepyrrolidine-2,5-dione, α,β-unsaturated carbonyl compound, substituted (S)-3-(1,3-dioxo-2,3-dihydroindeno[1,2-c]pyrrol-3a(1H)-yl)propanal, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCarbene Transfer, Further reactions Michael Addition, acetylacetone, (E)-β-nitrostyrene, (S)-3-(2-nitro-1-phenylethyl)pentane-2,4-dione, 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition Michael Addition, substituted 1-oxo-2,3-dihydro-1H-indene-2-carboxylate, terminal alkenes, substituted (S)-2-substituted-1-oxo-2,3-dihydro-1H-indene-2-carboxylate, (9S)-(9′′S)-1,1′′-[9,10-anthracenediylbis(methylene)]bis[9-hydroxy-6′-methoxy-cinchonanium chloride, Quinidine DerivativeMichael, Michael Addition Michael Addition, substituted 1-oxo-2,3-dihydro-1H-indene-2-carboxylate, terminal alkenes, substituted (R)-2-substituted-1-oxo-2,3-dihydro-1H-indene-2-carboxylate, (8α,9R)-(8′′α,9′′R)-1,1′′-[9,10-anthracenediylbis(methylene)]bis[9-hydroxy-6′-methoxy-cinchonanium chloride, Quinine DerivativeMichael, Michael Addition Spirocyclization, substituted 3-(2-methylallyl)cyclohex-2-en-1-one, oxindoles, dispirooxindole derivatives, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine Derivative[4+2]-Cycloaddition, Cycloaddition, Spirocyclization Cross-Coupling, terminal alkenes, terminal alkynes, hetetrocycles, heterocyclic acetylene compounds, copper catalyst, 2-[Bis[3,5-bis(1,1-dimethylethyl)phenyl]phosphino]- N-[(8α,9S)-6′-methoxycinchonan-9-yl]benzamide, Quinine DerivativeCross Coupling Atropisomer Synthesis, 1-phenyl-3-(2-phenyl-1H-indol-1-yl)prop-2-yn-1-one, tert-butyl 2-isocyanoacetate, tert-butyl 4-benzoyl-3-(2-phenyl-1H-indol-1-yl)-1H-pyrrole-2-carboxylate, silver acetate, 2-(diphenylphosphino)-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-benzamide, Quinine DerivativeAtropisomer synthesis Isoxazoline Cyclization, (Z)-4-(3-(3-chloro-5-(trifluoromethyl)phenyl)-4,4,4-trifluorobut-2-enoyl)-N-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-1-naphthamide, hydroxylamine, (s)-afoxolaner, (8α,9R)-9-hydroxy-6′-methoxy-1-[[3,4,5-tris[(4-methylphenyl)methyl]phenyl]methyl]-cinchonanium chloride, Quinine DerivativeCyclization, Isoxazoline cyclization Isoxazoline Cyclization, (Z)-4-(3-(3-chloro-5-(trifluoromethyl)phenyl)-4,4,4-trifluorobut-2-enoyl)-N-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-1-naphthamide, hydroxylamine, (s)-afoxolaner, N-(9-Acridinylmethyl)quininium Bromide, Quinine DerivativeCyclization, Isoxazoline cyclization« Older Entries
Cascade reaction, 4-(2-(methylthio)ethyl)-2-phenyloxazol-5(4H)-one, (E)-3-(2-hydroxyphenyl)-1-phenylprop-2-en-1-one, 3,4‐dihydrocoumarins, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCascade reaction
Carbene Transfer, substituted 3-diazo-4-methylenepyrrolidine-2,5-dione, α,β-unsaturated carbonyl compound, substituted (S)-3-(1,3-dioxo-2,3-dihydroindeno[1,2-c]pyrrol-3a(1H)-yl)propanal, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCarbene Transfer, Further reactions
Michael Addition, acetylacetone, (E)-β-nitrostyrene, (S)-3-(2-nitro-1-phenylethyl)pentane-2,4-dione, 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition
Michael Addition, substituted 1-oxo-2,3-dihydro-1H-indene-2-carboxylate, terminal alkenes, substituted (S)-2-substituted-1-oxo-2,3-dihydro-1H-indene-2-carboxylate, (9S)-(9′′S)-1,1′′-[9,10-anthracenediylbis(methylene)]bis[9-hydroxy-6′-methoxy-cinchonanium chloride, Quinidine DerivativeMichael, Michael Addition
Michael Addition, substituted 1-oxo-2,3-dihydro-1H-indene-2-carboxylate, terminal alkenes, substituted (R)-2-substituted-1-oxo-2,3-dihydro-1H-indene-2-carboxylate, (8α,9R)-(8′′α,9′′R)-1,1′′-[9,10-anthracenediylbis(methylene)]bis[9-hydroxy-6′-methoxy-cinchonanium chloride, Quinine DerivativeMichael, Michael Addition
Spirocyclization, substituted 3-(2-methylallyl)cyclohex-2-en-1-one, oxindoles, dispirooxindole derivatives, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine Derivative[4+2]-Cycloaddition, Cycloaddition, Spirocyclization
Cross-Coupling, terminal alkenes, terminal alkynes, hetetrocycles, heterocyclic acetylene compounds, copper catalyst, 2-[Bis[3,5-bis(1,1-dimethylethyl)phenyl]phosphino]- N-[(8α,9S)-6′-methoxycinchonan-9-yl]benzamide, Quinine DerivativeCross Coupling
Atropisomer Synthesis, 1-phenyl-3-(2-phenyl-1H-indol-1-yl)prop-2-yn-1-one, tert-butyl 2-isocyanoacetate, tert-butyl 4-benzoyl-3-(2-phenyl-1H-indol-1-yl)-1H-pyrrole-2-carboxylate, silver acetate, 2-(diphenylphosphino)-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-benzamide, Quinine DerivativeAtropisomer synthesis
Isoxazoline Cyclization, (Z)-4-(3-(3-chloro-5-(trifluoromethyl)phenyl)-4,4,4-trifluorobut-2-enoyl)-N-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-1-naphthamide, hydroxylamine, (s)-afoxolaner, (8α,9R)-9-hydroxy-6′-methoxy-1-[[3,4,5-tris[(4-methylphenyl)methyl]phenyl]methyl]-cinchonanium chloride, Quinine DerivativeCyclization, Isoxazoline cyclization
Isoxazoline Cyclization, (Z)-4-(3-(3-chloro-5-(trifluoromethyl)phenyl)-4,4,4-trifluorobut-2-enoyl)-N-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-1-naphthamide, hydroxylamine, (s)-afoxolaner, N-(9-Acridinylmethyl)quininium Bromide, Quinine DerivativeCyclization, Isoxazoline cyclization
