Michael Addition, indolyl ketones, nitromethane, (R)-3-(1H-indol-1-yl)-4-nitro-1-phenylbutan-1-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Dihydroquinidine DerivativeMichael, Michael Addition Atropisomer synthesis, 8‐arylquinolines, halogenating agent, atropisomeric 8‐arylquinolines, N-[3,5-bis(trifluoromethyl)phenyl]-N′- [(9R)-6′-methoxycinchonan-9-yl]-urea, Quinidine DerivativeAtropisomer synthesis, Bromination, Iodination Aldol reaction, alpha-azido ketones, ethyl 2-oxopropanoate, substituted ethyl 3-azido-2-hydroxy-2-methyl-4-oxo-4-phenylbutanoate, N-[3,5-bis(trifluoromethyl)phenyl]-N′- [(9R)-6′-methoxycinchonan-9-yl]-urea, Quinidine DerivativeAldol, Aldol alpha-Hydroxylation, substituted 1-oxo-2,3-dihydro-1H-indene-2-carboxylate, substituted 1-oxo-2,3-dihydro-1H-indene-2-carboxamide, (2-hydroperoxypropan-2-yl)benzene, substituted 2-hydroxy-1-oxo-2,3-dihydro-1H-indene-2-carboxylate, substituted 2-hydroxy-1-oxo-2,3-dihydro-1H-indene-2-carboxamide, (8α,9R)-1-[[4-fluoro-2-(trifluoromethyl)phenyl]methyl]-6′,9-dihydroxy-cinchonanium bromide, Cupreine DerivativeHydroxylation Alpha-Chlorination, 2-phenylacetyl chloride, 2,3,4,5,6,6-hexachlorocyclohexa-2,4-dien-1-one, perchlorophenyl (R)-2-chloro-2-phenylacetate, 6′-methoxy-(9S)-cinchonan-9-ol-9-benzoate, Quinidine DerivativeChlorination Michael Addition, substituted aminoacetonitrile, (E)-but-2-enal, α-aminonitriles, (9S)-9-[(6-chloro-2,5-diphenyl-4-pyrimidinyl)oxy]-1-[[2′-(1,1-dimethylethoxy)-3,3′,4,4′,5,5′-hexamethoxy[1,1′:3′,1′′-terphenyl]-5′-yl]methyl]-cinchonanium bromide, Cinchonine DerivativeMichael, Michael Addition Alkylation, N-acyl sulfenamides, benzyl bromide, sulfilimines, (9S)-9-hydroxy-1-(phenylmethyl)-Cinchonanium chloride, Cinchonine DerivativeAlkylation, S-Alkylation Spirocyclization, indene-based dienes, 3-phenylisoxazol-5(4H)-one, spirodihydrofluorenes, N-[3,5-bis(trifluoromethyl)phenyl]-N′-(9R)-cinchonan-9-yl-thiourea, Cinchonine DerivativeSpirocyclization Barbier Reaction, methyl 2,2-dimethyl-3-oxopropanoate, allyl bromide, methyl (S)-3-hydroxy-2,2-dimethylhex-5-enoate, indium, Cinchonine BaseBarbier Reaction, Further reactions Cyclization, 2-aryl acrylic acid, acrylates, butenolides, rhodium catalyst, Cinchonine Base[4+2] Annulation, Cyclization, Further Cyclizations, Michael Addition, Oxa-Michael Addition« Older Entries
Michael Addition, indolyl ketones, nitromethane, (R)-3-(1H-indol-1-yl)-4-nitro-1-phenylbutan-1-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Dihydroquinidine DerivativeMichael, Michael Addition
Atropisomer synthesis, 8‐arylquinolines, halogenating agent, atropisomeric 8‐arylquinolines, N-[3,5-bis(trifluoromethyl)phenyl]-N′- [(9R)-6′-methoxycinchonan-9-yl]-urea, Quinidine DerivativeAtropisomer synthesis, Bromination, Iodination
Aldol reaction, alpha-azido ketones, ethyl 2-oxopropanoate, substituted ethyl 3-azido-2-hydroxy-2-methyl-4-oxo-4-phenylbutanoate, N-[3,5-bis(trifluoromethyl)phenyl]-N′- [(9R)-6′-methoxycinchonan-9-yl]-urea, Quinidine DerivativeAldol, Aldol
alpha-Hydroxylation, substituted 1-oxo-2,3-dihydro-1H-indene-2-carboxylate, substituted 1-oxo-2,3-dihydro-1H-indene-2-carboxamide, (2-hydroperoxypropan-2-yl)benzene, substituted 2-hydroxy-1-oxo-2,3-dihydro-1H-indene-2-carboxylate, substituted 2-hydroxy-1-oxo-2,3-dihydro-1H-indene-2-carboxamide, (8α,9R)-1-[[4-fluoro-2-(trifluoromethyl)phenyl]methyl]-6′,9-dihydroxy-cinchonanium bromide, Cupreine DerivativeHydroxylation
Alpha-Chlorination, 2-phenylacetyl chloride, 2,3,4,5,6,6-hexachlorocyclohexa-2,4-dien-1-one, perchlorophenyl (R)-2-chloro-2-phenylacetate, 6′-methoxy-(9S)-cinchonan-9-ol-9-benzoate, Quinidine DerivativeChlorination
Michael Addition, substituted aminoacetonitrile, (E)-but-2-enal, α-aminonitriles, (9S)-9-[(6-chloro-2,5-diphenyl-4-pyrimidinyl)oxy]-1-[[2′-(1,1-dimethylethoxy)-3,3′,4,4′,5,5′-hexamethoxy[1,1′:3′,1′′-terphenyl]-5′-yl]methyl]-cinchonanium bromide, Cinchonine DerivativeMichael, Michael Addition
Alkylation, N-acyl sulfenamides, benzyl bromide, sulfilimines, (9S)-9-hydroxy-1-(phenylmethyl)-Cinchonanium chloride, Cinchonine DerivativeAlkylation, S-Alkylation
Spirocyclization, indene-based dienes, 3-phenylisoxazol-5(4H)-one, spirodihydrofluorenes, N-[3,5-bis(trifluoromethyl)phenyl]-N′-(9R)-cinchonan-9-yl-thiourea, Cinchonine DerivativeSpirocyclization
Barbier Reaction, methyl 2,2-dimethyl-3-oxopropanoate, allyl bromide, methyl (S)-3-hydroxy-2,2-dimethylhex-5-enoate, indium, Cinchonine BaseBarbier Reaction, Further reactions
Cyclization, 2-aryl acrylic acid, acrylates, butenolides, rhodium catalyst, Cinchonine Base[4+2] Annulation, Cyclization, Further Cyclizations, Michael Addition, Oxa-Michael Addition
