Amination, boron heterocycle, benzenesulfonimidamide, 1,5‐heteroatom (sulfur/boron) stereogenic architectures, (8α,9R)-1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-9-hydroxy-6′-methoxy-cinchonanium bromide, Quinine DerivativeAmination Atropisomer Synthesis, bromonitroalkenes, naphthalen-2-ol, (Z)-2-(2-bromo-2-nitrovinyl)-1-(2-methoxyphenyl)naphthalene, (1R,2R)-1-((S)-1-(2-methoxyphenyl)naphthalen-2-yl)-2-nitro-1,2-dihydronaphtho[2,1-b]furan, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAtropisomer synthesis, Kinetic resolution, Resolution Mannich reaction, substituted benzo[d]thiazol-2-amine, malonates, 2-((benzo[d]thiazol-2-ylamino)methyl)malonates, N-[2,6-dichloro-4-(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]-thiourea, Quinine DerivativeMannich, Mannich Strecker Reaction, α-amido sulfones, cyanohydrins, N-protected (S)-2-amino-3,3-dimethylbutanenitrile, 9-hydroxy-6′-methoxy-1-[[2-(trifluoromethyl)phenyl]methyl]-cinchonanium bromide, Quinine DerivativeStrecker Mannich reaction, 1-(diphenylphosphoryl)propan-2-one, α-amidosulfones, β-amino-α-methylene carbonyl, (8α,9R)-9-hydroxy-6′-methoxy-1-[(2-methoxyphenyl)methyl]-cinchonanium chloride, Quinine DerivativeMannich, Mannich Cycloaddition, para‐quinamines, cyclic N‐sulfonyl ketimines, imidazolidine‐fused benzosultam derivatives, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative[3+2]-Cycloaddition, Cycloaddition Mannich reaction, methyl 2-oxocyclopentane-1-carboxylate, α‐amido sulfones, substituted 1-(amino(phenyl)methyl)-2-oxocyclopentane-1-carboxylate, (8α,9R)-9-hydroxy-6′-methoxy-1-[(2-methoxyphenyl)methyl]-cinchonanium chloride, Quinine DerivativeMannich, Mannich Desymmetrization, substituted coumarin, cyclohexadienones, substituted 4-((5-oxocyclohex-3-en-1-yl)methyl)-2H-chromen-2-one, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeDesymmetrization Michael Addition, 1-(2-hydroxyphenyl)butane-1,3-dione, (E)-(2-nitrovinyl)benzene, β-nitro chromones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative[3+2] Annulation, Cascade reaction, Cyclization, Further Cyclizations, Michael, Michael Addition Cycloaddition, cyclic nitrones, meldrum’s acid, substituted isoxazolidinone, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-N′-[4-(trifluoromethyl)phenyl]-urea, Quinine Derivative[3+2]-Cycloaddition, Cycloaddition« Older Entries
Amination, boron heterocycle, benzenesulfonimidamide, 1,5‐heteroatom (sulfur/boron) stereogenic architectures, (8α,9R)-1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-9-hydroxy-6′-methoxy-cinchonanium bromide, Quinine DerivativeAmination
Atropisomer Synthesis, bromonitroalkenes, naphthalen-2-ol, (Z)-2-(2-bromo-2-nitrovinyl)-1-(2-methoxyphenyl)naphthalene, (1R,2R)-1-((S)-1-(2-methoxyphenyl)naphthalen-2-yl)-2-nitro-1,2-dihydronaphtho[2,1-b]furan, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAtropisomer synthesis, Kinetic resolution, Resolution
Mannich reaction, substituted benzo[d]thiazol-2-amine, malonates, 2-((benzo[d]thiazol-2-ylamino)methyl)malonates, N-[2,6-dichloro-4-(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]-thiourea, Quinine DerivativeMannich, Mannich
Strecker Reaction, α-amido sulfones, cyanohydrins, N-protected (S)-2-amino-3,3-dimethylbutanenitrile, 9-hydroxy-6′-methoxy-1-[[2-(trifluoromethyl)phenyl]methyl]-cinchonanium bromide, Quinine DerivativeStrecker
Mannich reaction, 1-(diphenylphosphoryl)propan-2-one, α-amidosulfones, β-amino-α-methylene carbonyl, (8α,9R)-9-hydroxy-6′-methoxy-1-[(2-methoxyphenyl)methyl]-cinchonanium chloride, Quinine DerivativeMannich, Mannich
Cycloaddition, para‐quinamines, cyclic N‐sulfonyl ketimines, imidazolidine‐fused benzosultam derivatives, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative[3+2]-Cycloaddition, Cycloaddition
Mannich reaction, methyl 2-oxocyclopentane-1-carboxylate, α‐amido sulfones, substituted 1-(amino(phenyl)methyl)-2-oxocyclopentane-1-carboxylate, (8α,9R)-9-hydroxy-6′-methoxy-1-[(2-methoxyphenyl)methyl]-cinchonanium chloride, Quinine DerivativeMannich, Mannich
Desymmetrization, substituted coumarin, cyclohexadienones, substituted 4-((5-oxocyclohex-3-en-1-yl)methyl)-2H-chromen-2-one, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeDesymmetrization
Michael Addition, 1-(2-hydroxyphenyl)butane-1,3-dione, (E)-(2-nitrovinyl)benzene, β-nitro chromones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative[3+2] Annulation, Cascade reaction, Cyclization, Further Cyclizations, Michael, Michael Addition
Cycloaddition, cyclic nitrones, meldrum’s acid, substituted isoxazolidinone, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-N′-[4-(trifluoromethyl)phenyl]-urea, Quinine Derivative[3+2]-Cycloaddition, Cycloaddition