Alkylation, N-acyl sulfenamides, benzyl bromide, sulfilimines, (9S)-9-hydroxy-1-(phenylmethyl)-Cinchonanium chloride, Cinchonine DerivativeAlkylation, S-Alkylation Spirocyclization, indene-based dienes, 3-phenylisoxazol-5(4H)-one, spirodihydrofluorenes, N-[3,5-bis(trifluoromethyl)phenyl]-N′-(9R)-cinchonan-9-yl-thiourea, Cinchonine DerivativeSpirocyclization Barbier Reaction, methyl 2,2-dimethyl-3-oxopropanoate, allyl bromide, methyl (S)-3-hydroxy-2,2-dimethylhex-5-enoate, indium, Cinchonine BaseBarbier Reaction, Further reactions Cyclization, 2-aryl acrylic acid, acrylates, butenolides, rhodium catalyst, Cinchonine Base[4+2] Annulation, Cyclization, Further Cyclizations, Michael Addition, Oxa-Michael Addition Spirocyclization, 3-isothiocyanato oxindoles, α-ketophosphonates, spirocycles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeSpirocyclization Friedel-Crafts Alkylation, 3‐trifluoroethylidene oxindoles, naphthols, dihydrocoumarins, 3-[[(3,5-dimethoxyphenyl)methyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeFriedel-Crafts, Friedel-Crafts alkylation, Lactonization Aza-Friedel-Crafts Alkylation, acenaphthenequinoneimines, naphthols, hemiketals, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAza-Friedel-Crafts, Friedel-Crafts Cyclization, substituted (E)-4-(5H-pyrrolo[3,2-d]pyrimidin-7-yl)but-3-en-1-amine, N-iodosuccinimide, 2-heteroaryl pyrrolidines, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeCyclization, Cyclization, Further Cyclizations, Iodination Michael Addition, 3‑aryloxindoles, ethenesulfonyl fluoride, substituted 2-(2-oxoindolin-3-yl)ethane-1-sulfonyl fluoride, 1,4-Bis[(9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-9,10-anthracenedione, Dihydroquinidine DerivativeMichael, Michael Addition Allylic Alkylation, 3-substituted benzofuran-2(3H)-ones, morita–baylis–hillman carbonates, substituted 2-((2-oxo-2,3-dihydrobenzofuran-3-yl)(phenyl)methyl)acrylate, 1,4-Bis[(9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-9,10-anthracenedione, Dihydroquinidine DerivativeAlkylation, Allylic Alkylation« Older Entries
Alkylation, N-acyl sulfenamides, benzyl bromide, sulfilimines, (9S)-9-hydroxy-1-(phenylmethyl)-Cinchonanium chloride, Cinchonine DerivativeAlkylation, S-Alkylation
Spirocyclization, indene-based dienes, 3-phenylisoxazol-5(4H)-one, spirodihydrofluorenes, N-[3,5-bis(trifluoromethyl)phenyl]-N′-(9R)-cinchonan-9-yl-thiourea, Cinchonine DerivativeSpirocyclization
Barbier Reaction, methyl 2,2-dimethyl-3-oxopropanoate, allyl bromide, methyl (S)-3-hydroxy-2,2-dimethylhex-5-enoate, indium, Cinchonine BaseBarbier Reaction, Further reactions
Cyclization, 2-aryl acrylic acid, acrylates, butenolides, rhodium catalyst, Cinchonine Base[4+2] Annulation, Cyclization, Further Cyclizations, Michael Addition, Oxa-Michael Addition
Spirocyclization, 3-isothiocyanato oxindoles, α-ketophosphonates, spirocycles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeSpirocyclization
Friedel-Crafts Alkylation, 3‐trifluoroethylidene oxindoles, naphthols, dihydrocoumarins, 3-[[(3,5-dimethoxyphenyl)methyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeFriedel-Crafts, Friedel-Crafts alkylation, Lactonization
Aza-Friedel-Crafts Alkylation, acenaphthenequinoneimines, naphthols, hemiketals, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAza-Friedel-Crafts, Friedel-Crafts
Cyclization, substituted (E)-4-(5H-pyrrolo[3,2-d]pyrimidin-7-yl)but-3-en-1-amine, N-iodosuccinimide, 2-heteroaryl pyrrolidines, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeCyclization, Cyclization, Further Cyclizations, Iodination
Michael Addition, 3‑aryloxindoles, ethenesulfonyl fluoride, substituted 2-(2-oxoindolin-3-yl)ethane-1-sulfonyl fluoride, 1,4-Bis[(9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-9,10-anthracenedione, Dihydroquinidine DerivativeMichael, Michael Addition
Allylic Alkylation, 3-substituted benzofuran-2(3H)-ones, morita–baylis–hillman carbonates, substituted 2-((2-oxo-2,3-dihydrobenzofuran-3-yl)(phenyl)methyl)acrylate, 1,4-Bis[(9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-9,10-anthracenedione, Dihydroquinidine DerivativeAlkylation, Allylic Alkylation
