Dihydroxylation, (S,E)-2-(12-substituted-heptadec-8-en-10-yn-1-yl)-1,3-dioxolane, (8S,9S,12S)-1-(1,3-dioxolan-2-yl)-12-substituted-heptadec-10-yne-8,9-diol, potassium ferrocyanide, potassium osmate(VI) dihydrate, (DHQ)2PHAL (8α,9R)-(8′′α,9′′R)-9,9′′-[1,4-Phthalazinediylbis(oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine DerivativeDihydroxylation, Further reactions Alkylation, (1-diazo-trifluoroethyl)benzene, water, N-protected indoline-2,3-dione, N-protected (S)-3-(1,1-difluoro-2-oxo-2-phenylethyl)-3-hydroxyindolin-2-one, rhodium catalyst, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine DerivativeAlkylation, Difluoroalkylation Atropisomer Synthesis, 1-(phenylethynyl)naphthalen-2-ol, Se-phenyl benzenesulfonoselenoate, (E)-1-(2-phenyl-2-(phenylselanyl)-1-(phenylsulfonyl)vinyl)naphthalen-2-ol, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAtropisomer synthesis Desymmetrization, substituted succinic anhydride, substituted glutaric anhydride, substituted 4-methoxy-4-oxobutanoic acid, 3R-substituted 5-methoxy-5-oxopentanoic acid, (+)-limonene, 3-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-4-[(1-pyrenylmethyl)amino]-3-cyclobutene-1,2-dione, Quinine DerivativeDesymmetrization Atropisomer Synthesis, 1-alkynylnaphthalen-2-ol, substituted pyrimidine-2,4,6-trione, barbiturate-substituted chiral styrenes, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine DerivativeAtropisomer synthesis Cyclization, substituted 3-nitrohex-2-en-4-yne, alpha-nitrilketones, 4 H-pyrans, copper(II) acetate, BINAP, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative[4+2] Annulation, Cascade reaction, Cyclization, Further Cyclizations, Michael, Michael Addition Cycloaddition, cyclic nitrones, O-hydroxystyrenes, substituted 2-(hexahydro-2H-isoxazolo[2,3-a]pyridin-2-yl)phenol, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine DerivativeCyclization, Cycloaddition Spirocyclization, methyleneindolinones, α-unsubstituted isocyanoacetates, spirooxindoles, 2-(diphenylphosphino)-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-benzamide, Quinine Derivative[3+2]-Cycloaddition, Cycloaddition, Spirocyclization Cascade reaction, 1,3-nitroenynes, isoxazole-5-ones, dihydropyranisoxazolines, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCascade reaction, Michael Addition, Oxa-Michael Addition Spirocyclization, substituted indoline-2,3-dione, nitriles, 1,2-dihydropyridazine-3,6-dione, spirooxindoles, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeKnoevenagel, Michael, Michael Addition, Spirocyclization« Older Entries
Dihydroxylation, (S,E)-2-(12-substituted-heptadec-8-en-10-yn-1-yl)-1,3-dioxolane, (8S,9S,12S)-1-(1,3-dioxolan-2-yl)-12-substituted-heptadec-10-yne-8,9-diol, potassium ferrocyanide, potassium osmate(VI) dihydrate, (DHQ)2PHAL (8α,9R)-(8′′α,9′′R)-9,9′′-[1,4-Phthalazinediylbis(oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine DerivativeDihydroxylation, Further reactions
Alkylation, (1-diazo-trifluoroethyl)benzene, water, N-protected indoline-2,3-dione, N-protected (S)-3-(1,1-difluoro-2-oxo-2-phenylethyl)-3-hydroxyindolin-2-one, rhodium catalyst, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine DerivativeAlkylation, Difluoroalkylation
Atropisomer Synthesis, 1-(phenylethynyl)naphthalen-2-ol, Se-phenyl benzenesulfonoselenoate, (E)-1-(2-phenyl-2-(phenylselanyl)-1-(phenylsulfonyl)vinyl)naphthalen-2-ol, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAtropisomer synthesis
Desymmetrization, substituted succinic anhydride, substituted glutaric anhydride, substituted 4-methoxy-4-oxobutanoic acid, 3R-substituted 5-methoxy-5-oxopentanoic acid, (+)-limonene, 3-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-4-[(1-pyrenylmethyl)amino]-3-cyclobutene-1,2-dione, Quinine DerivativeDesymmetrization
Atropisomer Synthesis, 1-alkynylnaphthalen-2-ol, substituted pyrimidine-2,4,6-trione, barbiturate-substituted chiral styrenes, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine DerivativeAtropisomer synthesis
Cyclization, substituted 3-nitrohex-2-en-4-yne, alpha-nitrilketones, 4 H-pyrans, copper(II) acetate, BINAP, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative[4+2] Annulation, Cascade reaction, Cyclization, Further Cyclizations, Michael, Michael Addition
Cycloaddition, cyclic nitrones, O-hydroxystyrenes, substituted 2-(hexahydro-2H-isoxazolo[2,3-a]pyridin-2-yl)phenol, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine DerivativeCyclization, Cycloaddition
Spirocyclization, methyleneindolinones, α-unsubstituted isocyanoacetates, spirooxindoles, 2-(diphenylphosphino)-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-benzamide, Quinine Derivative[3+2]-Cycloaddition, Cycloaddition, Spirocyclization
Cascade reaction, 1,3-nitroenynes, isoxazole-5-ones, dihydropyranisoxazolines, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCascade reaction, Michael Addition, Oxa-Michael Addition
Spirocyclization, substituted indoline-2,3-dione, nitriles, 1,2-dihydropyridazine-3,6-dione, spirooxindoles, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeKnoevenagel, Michael, Michael Addition, Spirocyclization
