Allylation, boc-protected methyl 2-(hydroxymethyl)acrylate, substituted benzimidoyl cyanide, substituted methyl (E)-4-((cyano(phenyl)methylene)amino)-2-methylenebutanoate, Dihydroquinidine BaseAlkylation, Allylation Cyclization, 1,5-dienes, potassium permanganate, tetrahydrofurans, (1S,2S,4S,5R)-2-((R)-(benzyloxy)(quinolin-4-yl)methyl)-1-(3,5-bis(trifluoromethyl)benzyl)-5-ethylquinuclidin-1-ium bromide, Dihydrocinchonidine DerivativeCyclization, Further Cyclizations [4+4] Annulation, benzylidene thiazolones, ynones, substituted 3a,8,9,9a-tetrahydro-7H-oxocino[2,3-d]thiazol-7-one, (8α,9S)-Cinchonan-9-amine, Cinchonidine Derivative[4+4] Annulation, Cyclization, Further Cyclizations Desymmetrization, organosilanes, di-tert-butyl dicarbonate, organosilanes, (8α,9R)-(8′′α,9′′R)-9,9′′-[1,4-Phthalazinediylbis (oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine DerivativeDesymmetrization Strecker Reaction, N-protected 2,2,2-trifluoro-1-phenylethan-1-imine, trimethylsilyl cyanide, N-protected 2-amino-3,3,3-trifluoro-2-phenylpropanenitrile, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)- 10,11-dihydro-6′-methoxycinchonan-9-yl]-Urea, Dihydroquinine DerivativeStrecker Strecker Reaction, fluoroalkyl ketones, substituted anilines, trimethylsilyl cyanide, substituted 3,3,3-trifluoro-2-(phenylamino)propanenitrile, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)- 10,11-dihydro-6′-methoxycinchonan-9-yl]-Urea, Dihydroquinine DerivativeStrecker Strecker Reaction, substituted 3-iminoindolin-2-one, trimethylsilyl cyanide, substituted (R)-3-amino-2-oxoindoline-3-carbonitrile, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeStrecker Strecker Reaction, substituted 3-iminoindolin-2-one, trimethylsilyl cyanide, substituted (R)-3-amino-2-oxoindoline-3-carbonitrile, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeStrecker Strecker Reaction, pyrazolones, trimethylsilyl cyanide, pyrazolone α-aminonitrile derivatives, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeStrecker Strecker Reaction, thiazole imines, trimethylsilyl cyanide, substituted 2-(benzo[d]thiazol-2-ylamino)acetonitrile, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeStrecker« Older Entries
Allylation, boc-protected methyl 2-(hydroxymethyl)acrylate, substituted benzimidoyl cyanide, substituted methyl (E)-4-((cyano(phenyl)methylene)amino)-2-methylenebutanoate, Dihydroquinidine BaseAlkylation, Allylation
Cyclization, 1,5-dienes, potassium permanganate, tetrahydrofurans, (1S,2S,4S,5R)-2-((R)-(benzyloxy)(quinolin-4-yl)methyl)-1-(3,5-bis(trifluoromethyl)benzyl)-5-ethylquinuclidin-1-ium bromide, Dihydrocinchonidine DerivativeCyclization, Further Cyclizations
[4+4] Annulation, benzylidene thiazolones, ynones, substituted 3a,8,9,9a-tetrahydro-7H-oxocino[2,3-d]thiazol-7-one, (8α,9S)-Cinchonan-9-amine, Cinchonidine Derivative[4+4] Annulation, Cyclization, Further Cyclizations
Desymmetrization, organosilanes, di-tert-butyl dicarbonate, organosilanes, (8α,9R)-(8′′α,9′′R)-9,9′′-[1,4-Phthalazinediylbis (oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine DerivativeDesymmetrization
Strecker Reaction, N-protected 2,2,2-trifluoro-1-phenylethan-1-imine, trimethylsilyl cyanide, N-protected 2-amino-3,3,3-trifluoro-2-phenylpropanenitrile, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)- 10,11-dihydro-6′-methoxycinchonan-9-yl]-Urea, Dihydroquinine DerivativeStrecker
Strecker Reaction, fluoroalkyl ketones, substituted anilines, trimethylsilyl cyanide, substituted 3,3,3-trifluoro-2-(phenylamino)propanenitrile, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)- 10,11-dihydro-6′-methoxycinchonan-9-yl]-Urea, Dihydroquinine DerivativeStrecker
Strecker Reaction, substituted 3-iminoindolin-2-one, trimethylsilyl cyanide, substituted (R)-3-amino-2-oxoindoline-3-carbonitrile, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeStrecker
Strecker Reaction, substituted 3-iminoindolin-2-one, trimethylsilyl cyanide, substituted (R)-3-amino-2-oxoindoline-3-carbonitrile, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeStrecker
Strecker Reaction, pyrazolones, trimethylsilyl cyanide, pyrazolone α-aminonitrile derivatives, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeStrecker
Strecker Reaction, thiazole imines, trimethylsilyl cyanide, substituted 2-(benzo[d]thiazol-2-ylamino)acetonitrile, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeStrecker
