Desymmetrization, substituted succinic anhydride, substituted glutaric anhydride, substituted 4-methoxy-4-oxobutanoic acid, 3R-substituted 5-methoxy-5-oxopentanoic acid, (+)-limonene, 3-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-4-[(1-pyrenylmethyl)amino]-3-cyclobutene-1,2-dione, Quinine DerivativeDesymmetrization Atropisomer Synthesis, 1-alkynylnaphthalen-2-ol, substituted pyrimidine-2,4,6-trione, barbiturate-substituted chiral styrenes, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine DerivativeAtropisomer synthesis Cyclization, substituted 3-nitrohex-2-en-4-yne, alpha-nitrilketones, 4 H-pyrans, copper(II) acetate, BINAP, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative[4+2] Annulation, Cascade reaction, Cyclization, Further Cyclizations, Michael, Michael Addition Cycloaddition, cyclic nitrones, O-hydroxystyrenes, substituted 2-(hexahydro-2H-isoxazolo[2,3-a]pyridin-2-yl)phenol, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine DerivativeCyclization, Cycloaddition Spirocyclization, methyleneindolinones, α-unsubstituted isocyanoacetates, spirooxindoles, 2-(diphenylphosphino)-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-benzamide, Quinine Derivative[3+2]-Cycloaddition, Cycloaddition, Spirocyclization Cascade reaction, 1,3-nitroenynes, isoxazole-5-ones, dihydropyranisoxazolines, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCascade reaction, Michael Addition, Oxa-Michael Addition Spirocyclization, substituted indoline-2,3-dione, nitriles, 1,2-dihydropyridazine-3,6-dione, spirooxindoles, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeKnoevenagel, Michael, Michael Addition, Spirocyclization Alpha Alkylation, (bromomethyl)benzenes, (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 2-((diphenylmethylene)amino)acetate, S-2,6-dimethyltyrosine derivatives, (8α,9R)-9-hydroxy-6′-methoxy-1-(4-pyrenylmethyl)-cinchonanium bromide, Quinine DerivativeAlkylation, alpha-Alkylation Spirocyclization, 3-(2-methylallyl)cyclohex-2-en-1-one, ethyl 2-oxo-2H-chromene-3-carboxylate, spiro-fused coumarins, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine Derivative[4+2]-Cycloaddition, Cycloaddition, Diels-Alder reaction, Spirocyclization Alkylation, N-(arylthio)benzamide, toluene, sulfilimines, copper catalyst, N-[(S)-[(1S,2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]oct-2-yl](6-methoxy-4-quinolinyl)methyl]-8-quinolinesulfonamide, Quinine DerivativeAlkylation, S-Alkylation« Older Entries
Desymmetrization, substituted succinic anhydride, substituted glutaric anhydride, substituted 4-methoxy-4-oxobutanoic acid, 3R-substituted 5-methoxy-5-oxopentanoic acid, (+)-limonene, 3-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-4-[(1-pyrenylmethyl)amino]-3-cyclobutene-1,2-dione, Quinine DerivativeDesymmetrization
Atropisomer Synthesis, 1-alkynylnaphthalen-2-ol, substituted pyrimidine-2,4,6-trione, barbiturate-substituted chiral styrenes, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine DerivativeAtropisomer synthesis
Cyclization, substituted 3-nitrohex-2-en-4-yne, alpha-nitrilketones, 4 H-pyrans, copper(II) acetate, BINAP, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative[4+2] Annulation, Cascade reaction, Cyclization, Further Cyclizations, Michael, Michael Addition
Cycloaddition, cyclic nitrones, O-hydroxystyrenes, substituted 2-(hexahydro-2H-isoxazolo[2,3-a]pyridin-2-yl)phenol, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine DerivativeCyclization, Cycloaddition
Spirocyclization, methyleneindolinones, α-unsubstituted isocyanoacetates, spirooxindoles, 2-(diphenylphosphino)-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-benzamide, Quinine Derivative[3+2]-Cycloaddition, Cycloaddition, Spirocyclization
Cascade reaction, 1,3-nitroenynes, isoxazole-5-ones, dihydropyranisoxazolines, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCascade reaction, Michael Addition, Oxa-Michael Addition
Spirocyclization, substituted indoline-2,3-dione, nitriles, 1,2-dihydropyridazine-3,6-dione, spirooxindoles, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeKnoevenagel, Michael, Michael Addition, Spirocyclization
Alpha Alkylation, (bromomethyl)benzenes, (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 2-((diphenylmethylene)amino)acetate, S-2,6-dimethyltyrosine derivatives, (8α,9R)-9-hydroxy-6′-methoxy-1-(4-pyrenylmethyl)-cinchonanium bromide, Quinine DerivativeAlkylation, alpha-Alkylation
Spirocyclization, 3-(2-methylallyl)cyclohex-2-en-1-one, ethyl 2-oxo-2H-chromene-3-carboxylate, spiro-fused coumarins, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine Derivative[4+2]-Cycloaddition, Cycloaddition, Diels-Alder reaction, Spirocyclization
Alkylation, N-(arylthio)benzamide, toluene, sulfilimines, copper catalyst, N-[(S)-[(1S,2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]oct-2-yl](6-methoxy-4-quinolinyl)methyl]-8-quinolinesulfonamide, Quinine DerivativeAlkylation, S-Alkylation
