Atropisomer Synthesis, substituted 2-(amino(phenyl)methylene)malonate, brominated hydrocarbons, atropisomers, (9S)-2′-[3,5-bis(1,1-dimethylethyl)phenyl]-9-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-[(3,4,5-trifluorophenyl)methyl]-6′-methoxy-cinchonanium bromide, Quinidine DerivativeAtropisomer synthesis Cross-Coupling, cyclopropyl halides, terminal alkynes, alkynyl cyclopropanes, copper(II) triflate, N-[(8α,9R)-2′-butyl-6′-methoxycinchonan-9-yl]-1-isoquinolinecarboxamide, Quinidine DerivativeCross Coupling Oxa-Michael, α,β-unsaturated carbonyl compound, 1,1‐disubstituted‐1,3‐dihydroisobenzofurans, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine Derivativeintramolecular Oxa-Michael Addition, Michael Addition, Oxa-Michael Addition Michael Addition, 2‐oxindole‐3‐carboxylate esters, 2‐phthalimido acrylates, substituted 2-oxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition [3+2] Annulation, cyclopropanes, nitrosoarenes, isoxazolidines, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine Derivative[3+2] Annulation, Cyclization, Further Cyclizations Amination, α-keto esters, arylmethanamines, α-Imino esters, (8α,9R)-9-[(6-chloro-2,5-diphenyl-4-pyrimidinyl)oxy]-1-[[2′-(1,1-dimethylethoxy)-3,3′′,4,4′′,5,5′′-hexamethoxy[1,1′:3′,3′′-terphenyl]-5′-yl]methyl]-6′-hydroxy-cinchonanium inner salt, Cupreine DerivativeAmination, Asymmetric Transamination, Isomerization Mannich reaction, ketimines, TosMIC, ((4S,5S)-5-methyl-5-phenyl-4-tosyl-4,5-dihydro-1H-imidazol-1-yl)diphenylphosphine oxide, silver catalyst, N-[(8α,9S)-10,11-dihydro-6′-methoxycinchonan -9-yl]-2-(diphenylphosphino)-benzamide, Dihydroquinine derivativeMannich, Mannich Resolution, 1-hydroxy-2,5-diphenylphospholane 1-oxide, (2S,5S)-1-hydroxy-2,5-diphenylphospholane 1-oxide, Quinine BaseResolution Alkylation, phosphinic acids, iodomethane, methyl (S)-(naphthalen-1-ylmethyl)(phenyl)phosphinate, (8α,9R)1-[(3,5-dimethylphenyl)methyl]-9-hydroxy-cinchonanium bromide, Cinchonidine DerivativeAlkylation, Alkylation Cascade Reaction, N-substituted Imines, substituted 3-methylenedihydrofuran-2(3H)-one, chiral amines, (8α,9R)-9-[(6-chloro-2,5-diphenyl-4-pyrimidinyl)oxy]-1-[[2′-(1,1-dimethylethoxy)-3,3′′,4,4′′,5,5′′-hexamethoxy[1,1′:3′,1′′-terphenyl]-5′-yl]methyl]-cinchonanium bromide, Cinchonidine DerivativeCascade reaction« Older Entries
Atropisomer Synthesis, substituted 2-(amino(phenyl)methylene)malonate, brominated hydrocarbons, atropisomers, (9S)-2′-[3,5-bis(1,1-dimethylethyl)phenyl]-9-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-[(3,4,5-trifluorophenyl)methyl]-6′-methoxy-cinchonanium bromide, Quinidine DerivativeAtropisomer synthesis
Cross-Coupling, cyclopropyl halides, terminal alkynes, alkynyl cyclopropanes, copper(II) triflate, N-[(8α,9R)-2′-butyl-6′-methoxycinchonan-9-yl]-1-isoquinolinecarboxamide, Quinidine DerivativeCross Coupling
Oxa-Michael, α,β-unsaturated carbonyl compound, 1,1‐disubstituted‐1,3‐dihydroisobenzofurans, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine Derivativeintramolecular Oxa-Michael Addition, Michael Addition, Oxa-Michael Addition
Michael Addition, 2‐oxindole‐3‐carboxylate esters, 2‐phthalimido acrylates, substituted 2-oxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition
[3+2] Annulation, cyclopropanes, nitrosoarenes, isoxazolidines, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine Derivative[3+2] Annulation, Cyclization, Further Cyclizations
Amination, α-keto esters, arylmethanamines, α-Imino esters, (8α,9R)-9-[(6-chloro-2,5-diphenyl-4-pyrimidinyl)oxy]-1-[[2′-(1,1-dimethylethoxy)-3,3′′,4,4′′,5,5′′-hexamethoxy[1,1′:3′,3′′-terphenyl]-5′-yl]methyl]-6′-hydroxy-cinchonanium inner salt, Cupreine DerivativeAmination, Asymmetric Transamination, Isomerization
Mannich reaction, ketimines, TosMIC, ((4S,5S)-5-methyl-5-phenyl-4-tosyl-4,5-dihydro-1H-imidazol-1-yl)diphenylphosphine oxide, silver catalyst, N-[(8α,9S)-10,11-dihydro-6′-methoxycinchonan -9-yl]-2-(diphenylphosphino)-benzamide, Dihydroquinine derivativeMannich, Mannich
Resolution, 1-hydroxy-2,5-diphenylphospholane 1-oxide, (2S,5S)-1-hydroxy-2,5-diphenylphospholane 1-oxide, Quinine BaseResolution
Alkylation, phosphinic acids, iodomethane, methyl (S)-(naphthalen-1-ylmethyl)(phenyl)phosphinate, (8α,9R)1-[(3,5-dimethylphenyl)methyl]-9-hydroxy-cinchonanium bromide, Cinchonidine DerivativeAlkylation, Alkylation
Cascade Reaction, N-substituted Imines, substituted 3-methylenedihydrofuran-2(3H)-one, chiral amines, (8α,9R)-9-[(6-chloro-2,5-diphenyl-4-pyrimidinyl)oxy]-1-[[2′-(1,1-dimethylethoxy)-3,3′′,4,4′′,5,5′′-hexamethoxy[1,1′:3′,1′′-terphenyl]-5′-yl]methyl]-cinchonanium bromide, Cinchonidine DerivativeCascade reaction
