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Atropisomer Synthesis, 2-hydroxynaphthalene-1,4-dione, 7-bromo-2-oxo-2H-chromene-3-carboxylic acid, naphthocoumarin atropisomers, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Atropisomer synthesis

Desymmetrization, sulfondiimines, 2,2,2-trifluoroethyl 2,2,2-trifluoroacetate, 2,2,2-trifluoro-N-(imino-sulfonylidene)acetamides, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-P,P-diphenyl-phosphinic amide, Quinine Derivative

Desymmetrization

Reduction, ketones, secondary alcohols, manganese catalyst, (R)-1-(quinolin-4-yl)-N-(thiophen-2-ylmethyl)-1-((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methanamine, Cinchonine Derivative

Hydrogenation, Hydrogenation of ketones, Reduction

Atropisomer Synthesis, substituted 5-phenyl-1H-pyrrole-3-carboxylic acid, atropisomer, Quinine Base

Atropisomer synthesis, Racemic resolution, Resolution

Spirocyclization, 3-Isothiocyanato oxindoles, (E)-5-(2-(substituted)vinyl)-3-methyl-4-nitroisoxazole, 3,3′-pyrrolidonyl spirooxindoles, Quinine Base

Spirocyclization

Cascade reaction, 4-(2-(methylthio)ethyl)-2-phenyloxazol-5(4H)-one, (E)-3-(2-hydroxyphenyl)-1-phenylprop-2-en-1-one, 3,4‐dihydrocoumarins, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative

Cascade reaction

Carbene Transfer, substituted 3-diazo-4-methylenepyrrolidine-2,5-dione, α,β-unsaturated carbonyl compound, substituted (S)-3-(1,3-dioxo-2,3-dihydroindeno[1,2-c]pyrrol-3a(1H)-yl)propanal, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative

Carbene Transfer, Further reactions

Michael Addition, acetylacetone, (E)-β-nitrostyrene, (S)-3-(2-nitro-1-phenylethyl)pentane-2,4-dione, 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative

Michael, Michael Addition

Michael Addition, substituted 1-oxo-2,3-dihydro-1H-indene-2-carboxylate, terminal alkenes, substituted (S)-2-substituted-1-oxo-2,3-dihydro-1H-indene-2-carboxylate, (9S)-(9′′S)-1,1′′-[9,10-anthracenediylbis(methylene)]bis[9-hydroxy-6′-methoxy-cinchonanium chloride, Quinidine Derivative

Michael, Michael Addition

Michael Addition, substituted 1-oxo-2,3-dihydro-1H-indene-2-carboxylate, terminal alkenes, substituted (R)-2-substituted-1-oxo-2,3-dihydro-1H-indene-2-carboxylate, (8α,9R)-(8′′α,9′′R)-1,1′′-[9,10-anthracenediylbis(methylene)]bis[9-hydroxy-6′-methoxy-cinchonanium chloride, Quinine Derivative

Michael, Michael Addition

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