Catalytic asymmetric strecker reaction: Bifunctional chiral tertiary amine/hydrogen-bond donor catalysis joins the field.

DOI Number:

10.1055/s-0034-1380117
Link to literature

Reaction Category:

Strecker

RXNO ID:

RXNO_0000207

Educt:

N-protected 2,2,2-trifluoro-1-phenylethan-1-imine, trimethylsilyl cyanide

Product:

N-protected 2-amino-3,3,3-trifluoro-2-phenylpropanenitrile

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)- 10,11-dihydro-6′-methoxycinchonan-9-yl]-Urea

Cas No:

871334-33-7

Associated Product from Buchler GmbH:

Dihydroquinine Base

Cas No:

522-66-7