Spirocyclization, (E)-7-chloro-3-ethylidene-1-methylindolin-2-one, diethyl 2-((2,2,2-trifluoroethyl)imino)malonate, diethyl (2’R,3R,4’S)-7-chloro-1,4′-dimethyl-2-oxo-2′-(trifluoromethyl)spiro[indoline-3,3′-pyrrolidine]-5′,5′-dicarboxylate, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [(8α,9S)-cinchonan-9-ylamino]- 3-Cyclobutene-1,2-dione, Cinchonidine Derivative by werner@buchler-gmbh.com | Mar 16, 2023
1,3 dipolar cycloaddition cascade, methyl-2-oxo-2H-pyran-3-carboxylate, (E)-1-methyl-3-((2,2,2-trifluoroethyl)imino)indolin-2-one, methyl (3S,3’R,3a’S,5a’S,6’R,8’R,8a’R,8b’S)-1,1”-dimethyl-2,2”,5′-trioxo-3′,8′-bis(trifluoromethyl)-3′,3a’,7′,8′,8a’,8b’-hexahydro-2’H-dispiro[indoline-3,1′-pyrano[2,3-c:4,5-c’]dipyrrole-6′,3”-indoline]-5a'(5’H)-carboxylate, Dihydroquinine Base by werner@buchler-gmbh.com | Feb 27, 2023
Hydrophosphonylation, (E)-N-benzylidene-6-methylpyridine-2-sulfonamide, diphenylphosphonate, diphenyl-(S)-(((6-methylpyridine)-2-sulfonamido)(phenyl)methyl)phosphonate, Dihydroquinine Base by werner@buchler-gmbh.com | Feb 27, 2023
Phospha Michael Addition, diphenyl phosphonate, (E)-2-(2-nitrovinyl)thiophene, diphenyl (R)-(2-nitro-1-(thiophen-2-yl)ethyl)phosphonate, Quinine Base by werner@buchler-gmbh.com | Feb 16, 2023
Desymmetrization, 4-((tert-butyldiphenylsilyl)oxy)dihydro-2H-pyran-2,6(3H)-dione, methanol, (R)-3-((tert-butyldiphenylsilyl)oxy)-5-methoxy-5-oxopentanoic acid, N-[(8α,9S)-6′-Methoxycinchonan-9-yl]- 3,5-bis(trifluoromethyl)benzenesulfonamide, Quinine Derivative by Anna-Lena Hartmann | Nov 7, 2022
