Buchler Glossary

Strecker reaction

The Strecker amino acid synthesis is a method for the synthesis of amino acids by the reaction of an aldehyde with ammonia in the presence of potassium cyanide. The condensation reaction yields an α-aminonitrile, which is subsequently hydrolyzed to give the desired amino acid.

Strecker reaction examples catalyzed by cinchona alkaloid derivatives can be found in our free of charge Chiral Catalyst Search.

Example from Literature

Asymmetric Activation of tropos 2,2′-Biphenol with Cinchonine Generates an Effective Catalyst for the Asymmetric Strecker Reaction of N-Tosyl-Protected Aldimines and Ketoimines. (Wang et al.; Angew. Chem. Int. Ed. 2007, 46, 44, 8468-8470.)

Strecker reaction

Further Articles:

Alkynylation

Alkynylation is an addition reaction in organic synthesis where a terminal alkyne adds to a carbonyl group to form an...

Allylsilylations

Allylsilylations are performed between allylsilanes and aldehydes furnishes homo allyl alcohols. Using Cinchona...

Aminohydroxylation

The Sharpless Aminohydroxylation allows the syn-selective preparation of 1,2-amino alcohols by reaction of alkenes...