Buchler Glossary

Morita–Baylis–Hillman reaction

Morita–Baylis–Hillman reaction is a carbon-carbon bond forming reaction between the α-position of an activated alkene and a carbon electrophile such as an aldehyde.

Morita–Baylis–Hillman reaction examples catalyzed by cinchona alkaloid derivatives can be found in our free of charge Chiral Catalyst Search Data Base.

Example from Literature

A Bifunctional β‐Isocupreidine Derivative as Catalyst for the Enantioselective Morita–Baylis–Hillman Reaction and a Mechanistic Rationale for Enantioselectivity. (Martelli et al.; Eur. J. Org. Chem. 2012, 2012(22), 4140-4152.)

Morita-Baylis-Hillman reaction

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