Chlorocyclization, alkeneamides, 1,3-dichloro-5,5-diphenylhydantoin, (5S,6R)-5-chloro-2,6-diphenyl-5,6-dihydro-4H-1,3-oxazine, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeChlorination, Cyclization, Cyclization, Further Cyclizations Mannich reaction, 4-benzyl-2-phenyloxazol-5(4H)-one, ethyl 2-((4-methylphenyl)sulfonamido)acrylate, α,β-diamino diacid derivatives, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeMannich, Mannich Atropisomer synthesis, (R)-2-acetylcyclopentan-1-one, N-(2-tert-butylphenyl) succinimides, (1R,1’S)-1′-acetyl-3-(2-(tert-butyl)-4-methoxyphenyl)-[1,1′-bi(cyclopentane)]-2,2′,4-trione, (9S,9′′S)-9,9′′-[(2,5-diphenyl-4,6-pyrimidinediyl)bis(oxy)] bis[10,11-dihydro-6′-methoxy-cinchonan], Dihydroquinidine DerivativeAtropisomer synthesis Aziridination, alkenyl alcohols, 2,2,3,3,3-pentafluoropropyl sulfamate, 2,2,3,3,3-pentafluoropropyl (2R,3S)-2-(2-hydroxyethyl)-3-(4-(trifluoromethyl)phenyl)aziridine-1-sulfonate, rhodium(II,II) tetracarboxylate dimer, (1S,2R,4S,5R)-5-ethyl-2-((S)-hydroxy(6-methoxyquinolin-4-yl)methyl)-1-((3,3”,5,5”-tetrakis(triethylsilyl)-[1,1′:3′,1”-terphenyl]-5′-yl)methyl)quinuclidin-1-ium, Dihydroquinidine DerivativeAziridination Spirocyclization, substituted 2-(2-oxo-1-tritylindolin-3-ylidene)malononitrile, substituted 2,4-dihydro-3H-pyrazol-3-one, spiro[indoline-3,4′-pyrano-[2,3-c]pyrazole] derivatives, (9S,9′′S)-9,9′′-[(2,5-diphenyl-4,6-pyrimidinediyl)bis(oxy)] bis[10,11-dihydro-6′-methoxy-cinchonan], Dihydroquinidine DerivativeSpirocyclization N-Allylic Alkylation, hydrazones, morita–baylis–hillman carbonates, methyl (S,E)-2-((2-benzylidene-1-tosylhydrazineyl)(phenyl)methyl)acrylate, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeAllylic Amination, Amination Oxa-Michael, ethyl (1R,2S,3R)-2-((E)-3-ethoxy-3-oxoprop-1-en-1-yl)-3-(2-hydroxyphenyl)cyclopropane-1-carboxylate, cyclopropane-fused chromanoles, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(9R)-10,11-dihydro-6′-methoxy cinchonan-9-yl]-thiourea, Dihydroquinidine DerivativeMichael Addition, Oxa-Michael Addition Allylation, allylic fluorides, silylated stabilized carbon nucleophiles, 5-substituted methyl (R)-3-(2-fluorophenyl)-2-methylene-5-oxopentanoate, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeAlkylation, Allylation Lactonization, 3-substituted 5-(tert-butyl) 1-methyl 2-methylenepentanedioate, diethyl 2-((tert-butoxycarbonyl)oxy)malonate, α-methylene-γ-lactones, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeLactonization Aldol reaction, isatins, acetaldehyde, substituted (S)-3-hydroxy-3-(2-hydroxyethyl)indolin-2-ones, benzoic acid, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeAldol, Aldol« Older EntriesNext Entries »
Chlorocyclization, alkeneamides, 1,3-dichloro-5,5-diphenylhydantoin, (5S,6R)-5-chloro-2,6-diphenyl-5,6-dihydro-4H-1,3-oxazine, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeChlorination, Cyclization, Cyclization, Further Cyclizations
Mannich reaction, 4-benzyl-2-phenyloxazol-5(4H)-one, ethyl 2-((4-methylphenyl)sulfonamido)acrylate, α,β-diamino diacid derivatives, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeMannich, Mannich
Atropisomer synthesis, (R)-2-acetylcyclopentan-1-one, N-(2-tert-butylphenyl) succinimides, (1R,1’S)-1′-acetyl-3-(2-(tert-butyl)-4-methoxyphenyl)-[1,1′-bi(cyclopentane)]-2,2′,4-trione, (9S,9′′S)-9,9′′-[(2,5-diphenyl-4,6-pyrimidinediyl)bis(oxy)] bis[10,11-dihydro-6′-methoxy-cinchonan], Dihydroquinidine DerivativeAtropisomer synthesis
Aziridination, alkenyl alcohols, 2,2,3,3,3-pentafluoropropyl sulfamate, 2,2,3,3,3-pentafluoropropyl (2R,3S)-2-(2-hydroxyethyl)-3-(4-(trifluoromethyl)phenyl)aziridine-1-sulfonate, rhodium(II,II) tetracarboxylate dimer, (1S,2R,4S,5R)-5-ethyl-2-((S)-hydroxy(6-methoxyquinolin-4-yl)methyl)-1-((3,3”,5,5”-tetrakis(triethylsilyl)-[1,1′:3′,1”-terphenyl]-5′-yl)methyl)quinuclidin-1-ium, Dihydroquinidine DerivativeAziridination
Spirocyclization, substituted 2-(2-oxo-1-tritylindolin-3-ylidene)malononitrile, substituted 2,4-dihydro-3H-pyrazol-3-one, spiro[indoline-3,4′-pyrano-[2,3-c]pyrazole] derivatives, (9S,9′′S)-9,9′′-[(2,5-diphenyl-4,6-pyrimidinediyl)bis(oxy)] bis[10,11-dihydro-6′-methoxy-cinchonan], Dihydroquinidine DerivativeSpirocyclization
N-Allylic Alkylation, hydrazones, morita–baylis–hillman carbonates, methyl (S,E)-2-((2-benzylidene-1-tosylhydrazineyl)(phenyl)methyl)acrylate, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeAllylic Amination, Amination
Oxa-Michael, ethyl (1R,2S,3R)-2-((E)-3-ethoxy-3-oxoprop-1-en-1-yl)-3-(2-hydroxyphenyl)cyclopropane-1-carboxylate, cyclopropane-fused chromanoles, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(9R)-10,11-dihydro-6′-methoxy cinchonan-9-yl]-thiourea, Dihydroquinidine DerivativeMichael Addition, Oxa-Michael Addition
Allylation, allylic fluorides, silylated stabilized carbon nucleophiles, 5-substituted methyl (R)-3-(2-fluorophenyl)-2-methylene-5-oxopentanoate, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeAlkylation, Allylation
Lactonization, 3-substituted 5-(tert-butyl) 1-methyl 2-methylenepentanedioate, diethyl 2-((tert-butoxycarbonyl)oxy)malonate, α-methylene-γ-lactones, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeLactonization
Aldol reaction, isatins, acetaldehyde, substituted (S)-3-hydroxy-3-(2-hydroxyethyl)indolin-2-ones, benzoic acid, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeAldol, Aldol
