Strecker Synthesis, spiro[cyclohexane-1,3′-indole], ethyl carbonocyanidate, (S)-spiro[cyclohexane-1,3′-indoline]-2′-carbonitrile, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeStrecker Isomerization, 5,5-dimethyl-3,4,5,6,7,8-hexahydronaphthalen-2(1H)-one, (S)-5,5-dimethyl-4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one, (R)-2-chloropropanoic acid, N1-[(9R)-6′-methoxycinchonan-9-yl]-4-(trifluoromethyl)-1,2-benzenediamine, Quinidine DerivativeIsomerization Atropisomer Synthesis, β-sulfinyl esters, substituted naphthalen-2-ol, sulfone-based axially chiral styrenes, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4- [[(9R)-6′-methoxycinchonan-9-yl]amino]-3- cyclobutene-1,2-dione, Quinidine DerivativeAtropisomer synthesis Desymmetrization, diethyl 3-oxobicyclo[3.1.0]hexane-6,6-dicarboxylate, diethyl (S)-2-(4-oxocyclopent-2-en-1-yl)malonate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′- methoxycinchonan-9-yl]thiourea, Quinidine DerivativeDesymmetrization Michael Addition, β-trifluoromethylated acrylamides, nitromethane, (R)-4-benzyl-3-((R)-4,4,4-trifluoro-3-(nitromethyl)butanoyl)oxazolidin-2-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′- methoxycinchonan-9-yl]thiourea, Quinidine DerivativeMichael, Michael Addition Hydrophosphonylation, 2,2,2-trifluoro-1-phenylethan-1-imine, diphenyl phosphonate, diphenyl (R)-(1-amino-2,2,2-trifluoro-1-phenylethyl)phosphonate, 3-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-4-[(4-methoxyphenyl)amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeHydrophosphonylation Cascade reaction, benzaldehyde, 2-(phenylsulfonyl)acetonitrile, methyl (R)-2-phenyl-2-(phenylamino)acetate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′- [(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine DerivativeCascade reaction Atropisomer Synthesis, substituted 4-acetyl-1-formamido-5-phenyl-1H-pyrrole-3-carboxylate, substituted 2-(((tert-butoxycarbonyl)oxy)methyl)acrylate, N–N axially chiral compounds, Quinidine BaseAtropisomer synthesis Alkylation, cyclic N‐sulfonyl ketimines, malonic acid half thioesters, substituted 2-(1,1-dioxido-2,3-dihydrobenzo[d]isothiazol-3-yl)ethanethioate, N-(9R)-cinchonan-9-yl-8-quinolinesulfonamide, Cinchonine DerivativeAlkylation, Alkylation, Mannich, Mannich Diels-Alder reaction, alkylidene pyrazolones, allyl ketones, tetrahydropyrano[2,3-c]pyrazoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCycloaddition, Diels-Alder reaction« Older EntriesNext Entries »
Strecker Synthesis, spiro[cyclohexane-1,3′-indole], ethyl carbonocyanidate, (S)-spiro[cyclohexane-1,3′-indoline]-2′-carbonitrile, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeStrecker
Isomerization, 5,5-dimethyl-3,4,5,6,7,8-hexahydronaphthalen-2(1H)-one, (S)-5,5-dimethyl-4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one, (R)-2-chloropropanoic acid, N1-[(9R)-6′-methoxycinchonan-9-yl]-4-(trifluoromethyl)-1,2-benzenediamine, Quinidine DerivativeIsomerization
Atropisomer Synthesis, β-sulfinyl esters, substituted naphthalen-2-ol, sulfone-based axially chiral styrenes, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4- [[(9R)-6′-methoxycinchonan-9-yl]amino]-3- cyclobutene-1,2-dione, Quinidine DerivativeAtropisomer synthesis
Desymmetrization, diethyl 3-oxobicyclo[3.1.0]hexane-6,6-dicarboxylate, diethyl (S)-2-(4-oxocyclopent-2-en-1-yl)malonate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′- methoxycinchonan-9-yl]thiourea, Quinidine DerivativeDesymmetrization
Michael Addition, β-trifluoromethylated acrylamides, nitromethane, (R)-4-benzyl-3-((R)-4,4,4-trifluoro-3-(nitromethyl)butanoyl)oxazolidin-2-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′- methoxycinchonan-9-yl]thiourea, Quinidine DerivativeMichael, Michael Addition
Hydrophosphonylation, 2,2,2-trifluoro-1-phenylethan-1-imine, diphenyl phosphonate, diphenyl (R)-(1-amino-2,2,2-trifluoro-1-phenylethyl)phosphonate, 3-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-4-[(4-methoxyphenyl)amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeHydrophosphonylation
Cascade reaction, benzaldehyde, 2-(phenylsulfonyl)acetonitrile, methyl (R)-2-phenyl-2-(phenylamino)acetate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′- [(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine DerivativeCascade reaction
Atropisomer Synthesis, substituted 4-acetyl-1-formamido-5-phenyl-1H-pyrrole-3-carboxylate, substituted 2-(((tert-butoxycarbonyl)oxy)methyl)acrylate, N–N axially chiral compounds, Quinidine BaseAtropisomer synthesis
Alkylation, cyclic N‐sulfonyl ketimines, malonic acid half thioesters, substituted 2-(1,1-dioxido-2,3-dihydrobenzo[d]isothiazol-3-yl)ethanethioate, N-(9R)-cinchonan-9-yl-8-quinolinesulfonamide, Cinchonine DerivativeAlkylation, Alkylation, Mannich, Mannich
Diels-Alder reaction, alkylidene pyrazolones, allyl ketones, tetrahydropyrano[2,3-c]pyrazoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCycloaddition, Diels-Alder reaction
