Asymmetric dearomatization of 2-nitrobenzofurans by organocatalyzed one-step Michael addition to access 3, 3′-disubstituted oxindoles.
DOI Number:
10.1039/C9CC09939E
Reaction Category:
Educt:
substituted 3-(1H-pyrrol-1-yl)indolin-2-one-2-nitrobenzofuran, substituted 2-nitrobenzofuran
Product:
substituted (S)-3-((2S,3S)-2-nitro-2,3-dihydrobenzofuran-3-yl)-3-(1H-pyrrol-1-yl)indolin-2-one
Catalyst:
(αS)-α-[[[[3,5-bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-(8α,9S)-cinchonan-9-yl-benzenepropanamide
Cas No:
1258793-27-9
Associated Product from Buchler GmbH:
Cinchonidine Base
Cas No:
485-71-2