Flow chemistry, benzylideneacetone, 4-hydroxycoumarin, (S)-warfarin, trifluoroacetic acid, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeFlow Chemistry, Michael, Michael Addition Spirocyclization, substituted oxindoles, methyl (E)-4-mercaptobut-2-enoate, substituted spirooxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction, Spirocyclization Spirocyclization, aromatic ketones, 6,5 spiroketals, 3-[[(8α,9S)-6′-Methoxycinchonan-9-yl]amino]-4-[[(1R)-1-(1-naphthalenyl)ethyl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeSpirocyclization Aldol reaction, 2-substituted ethyl 2-oxoacetate, nitromethane, 2-substituted ethyl 2-hydroxy-3-nitropropanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAldol, Henry, Henry, Nitroaldol Aza-Henry (Nitro-Mannich), substituted dibenzoxazepines, substituted dibenzothiazepines, nitromethane, substituted (R)-11-(nitromethyl)-10,11-dihydrodibenzo[b,f][1,4]oxazepine, substituted (R)-11-(nitromethyl)-10,11-dihydrodibenzo[b,f][1,4]thiazepine, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9R)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich Aza-Henry (Nitro-Mannich), substituted tert-butyl (E)-benzylidenecarbamate, primary nitroalkanes, substituted tert-butyl (2-nitro-1-phenylethyl)carbamate, 3-[(1,1-dimethylethyl)amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich Aza-Henry (Nitro-Mannich), trisubstituted cyclic amines, primary nitroalkanes, tetrasubstituted cyclic amines, diethylzinc, N-[(S)-[(1S,2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]oct-2-yl](6-methoxy-4-quinolinyl)methyl]-8-quinolinesulfonamide, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich Aza-Henry (Nitro-Mannich), substituted tert-butyl ((phenylsulfonyl)methyl)carbamate, 2-substituted 3-nitroprop-1-ene, tert-butyl ((1S,2S)-1,3-disubstituted-2-nitrobut-3-en-1-yl)carbamate, (8α,9S)-1-[[3,5-bis(1,1-dimethylethyl)phenyl] methyl]-9-[[[[(1S)-2-hydroxy-1-phenylethyl]amino]carbonyl]amino]-6′-methoxy-cinchonanium bromide, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich Aza-Henry (Nitro-Mannich), substituted 3H-indole, nitromethane, substituted (R)-2-(nitromethyl)indoline, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich Cyclization, (E)-2-(2-(benzylideneamino)phenyl)-2-phenylacetonitrile, (2R,3R)-2,3-diphenylindoline-3-carbonitrile, 9-hydroxy-6′-methoxy-1-(phenylmethyl)-cinchonanium chloride, Quinine DerivativeCyclization« Older EntriesNext Entries »
Flow chemistry, benzylideneacetone, 4-hydroxycoumarin, (S)-warfarin, trifluoroacetic acid, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeFlow Chemistry, Michael, Michael Addition
Spirocyclization, substituted oxindoles, methyl (E)-4-mercaptobut-2-enoate, substituted spirooxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction, Spirocyclization
Spirocyclization, aromatic ketones, 6,5 spiroketals, 3-[[(8α,9S)-6′-Methoxycinchonan-9-yl]amino]-4-[[(1R)-1-(1-naphthalenyl)ethyl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeSpirocyclization
Aldol reaction, 2-substituted ethyl 2-oxoacetate, nitromethane, 2-substituted ethyl 2-hydroxy-3-nitropropanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAldol, Henry, Henry, Nitroaldol
Aza-Henry (Nitro-Mannich), substituted dibenzoxazepines, substituted dibenzothiazepines, nitromethane, substituted (R)-11-(nitromethyl)-10,11-dihydrodibenzo[b,f][1,4]oxazepine, substituted (R)-11-(nitromethyl)-10,11-dihydrodibenzo[b,f][1,4]thiazepine, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9R)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich
Aza-Henry (Nitro-Mannich), substituted tert-butyl (E)-benzylidenecarbamate, primary nitroalkanes, substituted tert-butyl (2-nitro-1-phenylethyl)carbamate, 3-[(1,1-dimethylethyl)amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich
Aza-Henry (Nitro-Mannich), trisubstituted cyclic amines, primary nitroalkanes, tetrasubstituted cyclic amines, diethylzinc, N-[(S)-[(1S,2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]oct-2-yl](6-methoxy-4-quinolinyl)methyl]-8-quinolinesulfonamide, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich
Aza-Henry (Nitro-Mannich), substituted tert-butyl ((phenylsulfonyl)methyl)carbamate, 2-substituted 3-nitroprop-1-ene, tert-butyl ((1S,2S)-1,3-disubstituted-2-nitrobut-3-en-1-yl)carbamate, (8α,9S)-1-[[3,5-bis(1,1-dimethylethyl)phenyl] methyl]-9-[[[[(1S)-2-hydroxy-1-phenylethyl]amino]carbonyl]amino]-6′-methoxy-cinchonanium bromide, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich
Aza-Henry (Nitro-Mannich), substituted 3H-indole, nitromethane, substituted (R)-2-(nitromethyl)indoline, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich
Cyclization, (E)-2-(2-(benzylideneamino)phenyl)-2-phenylacetonitrile, (2R,3R)-2,3-diphenylindoline-3-carbonitrile, 9-hydroxy-6′-methoxy-1-(phenylmethyl)-cinchonanium chloride, Quinine DerivativeCyclization
