Hydrogenation, 1-(o-tolyl)ethan-1-one, (S)-1-(o-tolyl)ethan-1-ol, Di-μ-chlorobis[(1,2,5,6-η)-1,5-cyclooctadiene]diiridium, N-[[2-[bis(2-methoxyphenyl)phosphino]phenyl]methyl]-(8α,9S)-cinchonan-9-amine, Cinchonidine DerivativeHydrogenation, Hydrogenation of ketones Chlorocyclization, substituted N-(2-vinylphenyl)amide, 1,3-dichloro-5,5-dimethylimidazolidine-2,4-dione, substituted (S)-4-(chloromethyl)-4H-benzo[d][1,3]oxazine, 9-[2-[bis(2-methylphenyl)amino]benzoate]-(8α,9R)-Cinchonan-9-ol, Cinchonidine DerivativeChlorination, Cyclization, Cyclization, Further Cyclizations Chlorocyclization, substituted tert-butyl (2-vinylphenyl)carbamate, 1,3-dichloro-5,5-dimethylimidazolidine-2,4-dione, substituted (S)-4-(chloromethyl)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one, 9-[2-[bis(2-methylphenyl)amino]benzoate]-(8α,9R)-Cinchonan-9-ol, Cinchonidine DerivativeChlorination, Cyclization Trifluoromethylation, 4-bromo-2-(3-hydroxy-3-methylbutoxy)-9H-fluoren-9-one, trimethyl(trifluoromethyl)silane, (R)-4-bromo-2-(3-hydroxy-3-methylbutoxy)-9-(trifluoromethyl)-9H-fluoren-9-ol, 1-[[4-(1,1-dimethylethyl)-3-methoxyphenyl]methyl]-9-hydroxy-(8α,9R)-cinchonanium bromide, Cinchonidine DerivativeTrifluoromethylation Cross- Coupling, (Z)-N-(4-nitrobenzyl)-4-(triisopropylsilyl)but-3-yn-2-imine, methyl (E)-benzylidenecarbamate, methyl ((1S,2R)-2-methyl-2-(((E)-4-nitrobenzylidene)amino)-1-phenyl-4-(triisopropylsilyl)but-3-yn-1-yl)carbamate, methyl (E)-(2-(4-nitrophenyl)-1-phenyl-2-((4-(triisopropylsilyl)but-3-yn-2-ylidene)amino)ethyl)carbamate, 9-[(6-chloro-2,5-diphenyl-4-pyrimidinyl)oxy]-1-[[2′-(1,1-dimethylethoxy)-3,3′′,5,5′′-tetramethoxy[1,1′:3′,1′′-terphenyl]-5′-yl]methyl]-10,11-dihydro-11-[[tris(1-methylethyl)silyl]oxy]-(9R)-cinchonanium bromide, Cinchonidine DerivativeCross Coupling Allylation, (Z)-((3-bromoprop-1-en-1-yl)oxy)(tert-butyl)dimethylsilane, tert-butyl 2-((diphenylmethylene)amino)acetate, tert-butyl (S,Z)-6-((tert-butyldimethylsilyl)oxy)-2-((diphenylmethylene)amino)hex-4-enoate, 1-(9-anthracenylmethyl)-9-hydroxy-(8α,9R)-cinchonanium bromide, Cinchonidine DerivativeAlkylation, Allylation Spirocyclization, substituted (Z)-3-((2,2,2-trifluoroethyl)imino)indolin-2-one, substituted 1-methyl-3-methyleneindolin-2-one, substituted (3R,3’R,5’S)-1”-methyl-5′-(trifluoromethyl)dispiro[indoline-3,2′-pyrrolidine-3′,3”-indoline]-2,2”-dione, 3-[(8α,9S)-cinchonan-9-ylamino]-4-[[(1R)-1-phenylethyl]amino]-3-Cyclobutene-1,2-dione, Cinchonidine DerivativeSpirocyclization Spirocyclization, substituted (E)-3-((2,2,2-trifluoroethyl)imino)indolin-2-one, substituted (E)-nitroethene, substituted (3R,3’R,5’R)-3′-nitro-5′-(trifluoromethyl)spiro[indoline-3,2′-pyrrolidin]-2-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-cyclobutene-1,2-dione, Cinchonidine DerivativeSpirocyclization Hydrophosphonylation, 1-benzyl-3-iminoindolin-2-one, phosphonic acid ester, (R)-(3-amino-1-benzyl-2-oxoindolin-3-yl)phosphonic acid ester, 3-[(8α,9S)-cinchonan-9-ylamino]-4-[(4-methoxyphenyl)amino]-3-cyclobutene-1,2-dione, Cinchonidine DerivativeHydrophosphonylation Aza-Michael Addition, (E)-3-(1-methylindolin-2-yl)-1-phenylprop-2-en-1-one, 4-phenyl-1-(phenylsulfonyl)-1H-1,2,3-triazole, 2-((1R)-9-methyl-4-phenyl-2-(phenylsulfonyl)-2,4a,9,9a-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)-1-phenylethan-1-one, rhodium(II) acetate, 3-[(8α,9S)-cinchonan-9-ylamino]-4-[(phenylmethyl)amino]-3-Cyclobutene-1,2-dione, Cinchonidine DerivativeAza-Michael, Michael Addition« Older EntriesNext Entries »
Hydrogenation, 1-(o-tolyl)ethan-1-one, (S)-1-(o-tolyl)ethan-1-ol, Di-μ-chlorobis[(1,2,5,6-η)-1,5-cyclooctadiene]diiridium, N-[[2-[bis(2-methoxyphenyl)phosphino]phenyl]methyl]-(8α,9S)-cinchonan-9-amine, Cinchonidine DerivativeHydrogenation, Hydrogenation of ketones
Chlorocyclization, substituted N-(2-vinylphenyl)amide, 1,3-dichloro-5,5-dimethylimidazolidine-2,4-dione, substituted (S)-4-(chloromethyl)-4H-benzo[d][1,3]oxazine, 9-[2-[bis(2-methylphenyl)amino]benzoate]-(8α,9R)-Cinchonan-9-ol, Cinchonidine DerivativeChlorination, Cyclization, Cyclization, Further Cyclizations
Chlorocyclization, substituted tert-butyl (2-vinylphenyl)carbamate, 1,3-dichloro-5,5-dimethylimidazolidine-2,4-dione, substituted (S)-4-(chloromethyl)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one, 9-[2-[bis(2-methylphenyl)amino]benzoate]-(8α,9R)-Cinchonan-9-ol, Cinchonidine DerivativeChlorination, Cyclization
Trifluoromethylation, 4-bromo-2-(3-hydroxy-3-methylbutoxy)-9H-fluoren-9-one, trimethyl(trifluoromethyl)silane, (R)-4-bromo-2-(3-hydroxy-3-methylbutoxy)-9-(trifluoromethyl)-9H-fluoren-9-ol, 1-[[4-(1,1-dimethylethyl)-3-methoxyphenyl]methyl]-9-hydroxy-(8α,9R)-cinchonanium bromide, Cinchonidine DerivativeTrifluoromethylation
Cross- Coupling, (Z)-N-(4-nitrobenzyl)-4-(triisopropylsilyl)but-3-yn-2-imine, methyl (E)-benzylidenecarbamate, methyl ((1S,2R)-2-methyl-2-(((E)-4-nitrobenzylidene)amino)-1-phenyl-4-(triisopropylsilyl)but-3-yn-1-yl)carbamate, methyl (E)-(2-(4-nitrophenyl)-1-phenyl-2-((4-(triisopropylsilyl)but-3-yn-2-ylidene)amino)ethyl)carbamate, 9-[(6-chloro-2,5-diphenyl-4-pyrimidinyl)oxy]-1-[[2′-(1,1-dimethylethoxy)-3,3′′,5,5′′-tetramethoxy[1,1′:3′,1′′-terphenyl]-5′-yl]methyl]-10,11-dihydro-11-[[tris(1-methylethyl)silyl]oxy]-(9R)-cinchonanium bromide, Cinchonidine DerivativeCross Coupling
Allylation, (Z)-((3-bromoprop-1-en-1-yl)oxy)(tert-butyl)dimethylsilane, tert-butyl 2-((diphenylmethylene)amino)acetate, tert-butyl (S,Z)-6-((tert-butyldimethylsilyl)oxy)-2-((diphenylmethylene)amino)hex-4-enoate, 1-(9-anthracenylmethyl)-9-hydroxy-(8α,9R)-cinchonanium bromide, Cinchonidine DerivativeAlkylation, Allylation
Spirocyclization, substituted (Z)-3-((2,2,2-trifluoroethyl)imino)indolin-2-one, substituted 1-methyl-3-methyleneindolin-2-one, substituted (3R,3’R,5’S)-1”-methyl-5′-(trifluoromethyl)dispiro[indoline-3,2′-pyrrolidine-3′,3”-indoline]-2,2”-dione, 3-[(8α,9S)-cinchonan-9-ylamino]-4-[[(1R)-1-phenylethyl]amino]-3-Cyclobutene-1,2-dione, Cinchonidine DerivativeSpirocyclization
Spirocyclization, substituted (E)-3-((2,2,2-trifluoroethyl)imino)indolin-2-one, substituted (E)-nitroethene, substituted (3R,3’R,5’R)-3′-nitro-5′-(trifluoromethyl)spiro[indoline-3,2′-pyrrolidin]-2-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-cyclobutene-1,2-dione, Cinchonidine DerivativeSpirocyclization
Hydrophosphonylation, 1-benzyl-3-iminoindolin-2-one, phosphonic acid ester, (R)-(3-amino-1-benzyl-2-oxoindolin-3-yl)phosphonic acid ester, 3-[(8α,9S)-cinchonan-9-ylamino]-4-[(4-methoxyphenyl)amino]-3-cyclobutene-1,2-dione, Cinchonidine DerivativeHydrophosphonylation
Aza-Michael Addition, (E)-3-(1-methylindolin-2-yl)-1-phenylprop-2-en-1-one, 4-phenyl-1-(phenylsulfonyl)-1H-1,2,3-triazole, 2-((1R)-9-methyl-4-phenyl-2-(phenylsulfonyl)-2,4a,9,9a-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)-1-phenylethan-1-one, rhodium(II) acetate, 3-[(8α,9S)-cinchonan-9-ylamino]-4-[(phenylmethyl)amino]-3-Cyclobutene-1,2-dione, Cinchonidine DerivativeAza-Michael, Michael Addition
