Cascade reaction, 3-cinnamoyloxazolidin-2-one, 2-mercaptobenzaldehyde, 3-((2R,3S,4R)-4-hydroxy-2-phenylthiochromane-3-carbonyl)oxazolidin-2-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction Oxime addition, nitroalkenes, ethyl 2-(hydroxyimino)acetate, ethyl 2-((2-cyclohexyl-3-nitropropoxy)imino)acetate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAddition Desymmetrization, (3aR,4S,7R,7aS)-3a,4,7,7a-tetrahydro-4,7-methanoisobenzofuran-1,3-dione, methanol, (1R,2S,3R,4S)-3-(methoxycarbonyl)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeDesymmetrization β-Lactam Cyclization, acyl chlorides, ethyl (E)-2-(tosylimino)acetate, β-lactams, Benzoylquinine, Quinine Derivative[2+2]-Cycloaddition, Cycloaddition Michael Addition, α-substituted isocyanoacetates, N-aryl maleimides, substituted 2-((R)-2,5-dioxopyrrolidin-3-yl)-2-isocyanoacetate, 3-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-cyclobutene-1,2-dione, Quinine Derivative Desymmetrization, 4-(4-fluorophenyl)dihydro-2H-pyran-2,6(3H)-dione, methanol, (R)-3-(4-fluorophenyl)-5-methoxy-5-oxopentanoic acid, N-[(8α,9S)-6′-Methoxycinchonan-9-yl]- 3,5-bis(trifluoromethyl)benzenesulfonamide, Quinine DerivativeDesymmetrization Alkylation, 6,7-dichloro-5-methoxy-2-phenyl-2,3-dihydro-1H-inden-1-one, chloromethane, (S)-6,7-dichloro-5-methoxy-2-methyl-2-phenyl-2,3-dihydro-1H-inden-1-one, (8α,9R)-9-hydroxy-6′-methoxy-1-(phenylmethyl)-Cinchonanium bromide, Quinine DerivativeAlkylation, Alkylation Desymmetrization, (E)-4-phenylbut-3-en-2-one, prochiral maleimides, (3aR,7S,7aS)-2-(2-(tert-butyl)phenyl)-7-phenyltetrahydro-1H-isoindole-1,3,5(2H,4H)-trione, 1-hydroxy-2-naphthoic acid, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeAtropisomer synthesis, Desymmetrization Cyclization, substituted (E)-5,5,5-trifluoropent-3-en-2-one, hydroxylamine, trifluoromethyl‐substituted 2‐isoxazolines, 1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-9-hydroxy-6′-methoxy-cinchonanium bromide, Quinidine DerivativeCascade reaction, Cyclization, Cyclization, Further Cyclizations Desymmetrization, 3-isopropylcyclohex-2-en-1-one, prochiral maleimides, (R)-1-(2-(tert-butyl)phenyl)-3-(2-(3-oxocyclohex-1-en-1-yl)propan-2-yl)pyrrolidine-2,5-dione, (S)-2-((tert-butoxycarbonyl)amino)-2-phenylacetic acid, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeAtropisomer synthesis, Desymmetrization, Michael Addition, Vinylogous Michael Addition« Older EntriesNext Entries »
Cascade reaction, 3-cinnamoyloxazolidin-2-one, 2-mercaptobenzaldehyde, 3-((2R,3S,4R)-4-hydroxy-2-phenylthiochromane-3-carbonyl)oxazolidin-2-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction
Oxime addition, nitroalkenes, ethyl 2-(hydroxyimino)acetate, ethyl 2-((2-cyclohexyl-3-nitropropoxy)imino)acetate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAddition
Desymmetrization, (3aR,4S,7R,7aS)-3a,4,7,7a-tetrahydro-4,7-methanoisobenzofuran-1,3-dione, methanol, (1R,2S,3R,4S)-3-(methoxycarbonyl)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeDesymmetrization
β-Lactam Cyclization, acyl chlorides, ethyl (E)-2-(tosylimino)acetate, β-lactams, Benzoylquinine, Quinine Derivative[2+2]-Cycloaddition, Cycloaddition
Michael Addition, α-substituted isocyanoacetates, N-aryl maleimides, substituted 2-((R)-2,5-dioxopyrrolidin-3-yl)-2-isocyanoacetate, 3-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-cyclobutene-1,2-dione, Quinine Derivative
Desymmetrization, 4-(4-fluorophenyl)dihydro-2H-pyran-2,6(3H)-dione, methanol, (R)-3-(4-fluorophenyl)-5-methoxy-5-oxopentanoic acid, N-[(8α,9S)-6′-Methoxycinchonan-9-yl]- 3,5-bis(trifluoromethyl)benzenesulfonamide, Quinine DerivativeDesymmetrization
Alkylation, 6,7-dichloro-5-methoxy-2-phenyl-2,3-dihydro-1H-inden-1-one, chloromethane, (S)-6,7-dichloro-5-methoxy-2-methyl-2-phenyl-2,3-dihydro-1H-inden-1-one, (8α,9R)-9-hydroxy-6′-methoxy-1-(phenylmethyl)-Cinchonanium bromide, Quinine DerivativeAlkylation, Alkylation
Desymmetrization, (E)-4-phenylbut-3-en-2-one, prochiral maleimides, (3aR,7S,7aS)-2-(2-(tert-butyl)phenyl)-7-phenyltetrahydro-1H-isoindole-1,3,5(2H,4H)-trione, 1-hydroxy-2-naphthoic acid, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeAtropisomer synthesis, Desymmetrization
Cyclization, substituted (E)-5,5,5-trifluoropent-3-en-2-one, hydroxylamine, trifluoromethyl‐substituted 2‐isoxazolines, 1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-9-hydroxy-6′-methoxy-cinchonanium bromide, Quinidine DerivativeCascade reaction, Cyclization, Cyclization, Further Cyclizations
Desymmetrization, 3-isopropylcyclohex-2-en-1-one, prochiral maleimides, (R)-1-(2-(tert-butyl)phenyl)-3-(2-(3-oxocyclohex-1-en-1-yl)propan-2-yl)pyrrolidine-2,5-dione, (S)-2-((tert-butoxycarbonyl)amino)-2-phenylacetic acid, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeAtropisomer synthesis, Desymmetrization, Michael Addition, Vinylogous Michael Addition
