Organocatalytic desymmetrization reactions for the synthesis of axially chiral compounds.
DOI Number:
10.1002/tcr.201800194
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
3-isopropylcyclohex-2-en-1-one, prochiral maleimides
Product:
(R)-1-(2-(tert-butyl)phenyl)-3-(2-(3-oxocyclohex-1-en-1-yl)propan-2-yl)pyrrolidine-2,5-dione
Catalyst:
(S)-2-((tert-butoxycarbonyl)amino)-2-phenylacetic acid, (8α,9S)-6′-Methoxycinchonan-9-amine
Cas No:
168960-95-0
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0