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Hydrophosphonylation, trifluoromethyl 2(1H)-quinazolinones, dimethyl phosphonate, 4,4-disubstituted 2(1H)-quinazolinones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Hydrophosphonylation

Mannich reaction, methyl 3-oxo-2,3-dihydrobenzofuran-2-carboxylate, tert-butyl (E)-(1-methyl-2-oxoindolin-3-ylidene)carbamate, tetrasubstituted stereocenter containing 3-aminooxindole, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Mannich, Mannich

Phosphination, 1,2 disubstituted 2-diazoethan-1-one, disubstituted phosphine oxide, substituted (2-hydroxyethyl)phosphine oxide, 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine Derivative

Further reactions, Phosphination

Amination, substituted 3-oxopropanamide, di-tert-butyl (E)-diazene-1,2-dicarboxylate, serines, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine Derivative

alpha-Amination, Amination

Spirocyclization, oxindoles, pyrazolones, bi-spirocyclic compounds, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Cascade reaction, Spirocyclization

Spirocyclization, β,γ-unsaturated amides, oxindoles, spirooxindole-pyran derivatives, N-[(1S,2S)-2-[[[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]thioxomethyl]amino]-1,2-diphenylethyl]-4-methyl-benzenesulfonamide, Quinine Derivative

Cycloaddition, Diels-Alder reaction, Spirocyclization

Spirocyclization, enone-tethered 2,5-cyclohexadienone, isoxazolines, spiro-fused scaffolds, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative

Spirocyclization

Spirocyclization, unsaturated thiazolones, olefinic azlactones, spirocyclohexenone thiazolone skeletons, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Cycloaddition, Diels-Alder reaction, Spirocyclization

Atropisomer Synthesis, 7-iodo-1,3-dimethyl-5H-dibenzo[c,f]chromen-5-one, 1,3-bis(benzyloxy)propan-2-ol, aryne atropisomers, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Atropisomer synthesis

Michael Addition, 2-carboxythioesters-1,3-dithiane, nitroalkenes, substituted S-(2,2,2-trifluoroethyl) 2-(2-nitroethyl)-1,3-dithiane-2-carbothioate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Michael, Michael Addition

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