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Michael Addition, aldehydes, nitroolefins, 3R-substituted 2,2-dimethyl-4-nitrobutanal, N-[(1R,2R)-2-Aminocyclohexyl]-N′-[(8α,9S)- 6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Michael, Michael Addition

Spirocyclization, unsaturated pyrazolones, 3-aryl-2-nitroprop-2-enols, Spirotetrahydropyranopyrazolones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative

Michael Addition, Oxa-Michael Addition, Spirocyclization

Friedel−Crafts Alkylation, 1H-indole, α,β‐unsaturated trifluoromethyl ketones, 4S-substituted 1,1,1-trifluoro-4-(1H-indol-3-yl)butan-2-one, 3-[[3,5-bis(1,1-dimethylethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative

Friedel-Crafts, Friedel-Crafts alkylation

Michael Addition, nitroalkenes, nitroalkanes, 2-substituted 1,3-dinitropentane, 3-[(1,1-dimethylethyl)amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative

Michael, Michael Addition

Epoxidation Wharton-reaction sequence, 4,4-dimethylcyclohex-2-en-1-one, (R)-6,6-dimethylcyclohex-2-en-1-ol, (8α,9S)-6′-methoxy-Cinchonan-9-amine 2,2,2-trifluoroacetate (1:2), Quinine Derivative

Epoxidation, Further reactions, Wharton-reaction

Cyclopropanation, cyclic enones, bromonitromethane, bicyclic nitrocyclopropanes, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine Derivative

Cyclopropanation

Cyclopropanation, enones, bromonitromethane, nitrocyclopropanes, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine Derivative

Cyclopropanation

Diels-Alder, enones, 3-hydroxy-2H-pyran-2-one, bicyclic lactones, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine Derivative

Cycloaddition, Diels-Alder reaction

Aza-Michael Addition, enones, tert-butyl (benzyloxy)carbamate, substituted tert-butyl (benzyloxy)(3-oxopropyl)carbamate, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine Derivative

Aza-Michael, Michael Addition

Epoxidation, enones, hydroperoxides, epoxy ketones, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine Derivative

Epoxidation

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