Cyclopropanation, conjugated cyanosulfones, dimethyl 2-bromomalonate, 3-substituted dimethyl (2S,3R)-2-cyano-2-(phenylsulfonyl)cyclopropane-1,1-dicarboxylate, (8α,9R)-10,11-dihydro-9-(4-pentenoate)cinchonan-6′,9-diol, Dihydrocupreine DerivativeCyclopropanation Amination, Diethyl azodicarboxylate, ethyl 2-cyano-2-phenylacetate, 1,2-Diethyl 1-(1-cyano-2-ethoxy-2-oxo-1-phenylethyl)-1,2-hydrazinedicarboxylate, 3-[[[(1S)-2,2′-dihydroxy[1,1′-binaphthalen]-3-yl]methyl]amino]-4-[[(9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine Derivativealpha-Amination, Amination Amination, Diethyl azodicarboxylate, Methyl 2-oxocyclopentanecarboxylate, 1,2-Diethyl 1-[(1S)-1-(methoxycarbonyl)-2-oxocyclopentyl]-1,2-hydrazinedicarboxylate, 3-[[[(1S)-2,2′-dihydroxy[1,1′-binaphthalen]-3-yl]methyl]amino]-4-[[(9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine Derivativealpha-Amination, Amination Michael Addition, 2-hydroxy-1,4-naphthoquinone, nitroalkenes, substituted 2-hydroxy-3-(2-nitroethyl)naphthalene-1,4-dione, 3-[[[(1S)-2,2′-dihydroxy[1,1′-binaphthalen]-3-yl]methyl]amino]-4-[[(9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition Michael Addition, nitroalkenes, 1,3-dicarbonyl compounds, nitroalkanes, 3-[[[(1S)-2,2′-dihydroxy[1,1′-binaphthalen]-3-yl]methyl]amino]-4-[[(9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition Resolution, racemic 7′-hydroxy-2′,3′-dihydrospiro[chromane-4,1′-inden]-2-one, (R)-7′-hydroxy-2′,3′-dihydrospiro[chromane-4,1′-inden]-2-one, (8α,9R)-9-hydroxy-1-(phenylmethyl)-Cinchonanium chloride, Cinchonidine DerivativeResolution Cascade reaction, aminooxylating compounds, nitroolefins, tetrahydro 1,2-oxazines, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeCascade reaction Cascade reaction, N-Tosyl aminomethyl enones, trans-α-cyano-α,β-unsaturated ketones, highly substituted pyrrolidines, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione, Cinchonidine DerivativeCascade reaction Aza-Michael Addition, bidentate aminomethyl enones, N-tosyl imines, 2,4-disubstituted imidazolidines, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione, Cinchonidine DerivativeAza-Michael, Michael Addition Resolution, rac-BINOLs, (R)-BINOLs, N,N′-Di-tert-butylethylenediamine, Copper(I)-chloride, (8α,9R)-9-hydroxy-1-(phenylmethyl)-Cinchonanium chloride, Cinchonidine DerivativeAtropisomer synthesis, Racemic resolution, Resolution« Older EntriesNext Entries »
Cyclopropanation, conjugated cyanosulfones, dimethyl 2-bromomalonate, 3-substituted dimethyl (2S,3R)-2-cyano-2-(phenylsulfonyl)cyclopropane-1,1-dicarboxylate, (8α,9R)-10,11-dihydro-9-(4-pentenoate)cinchonan-6′,9-diol, Dihydrocupreine DerivativeCyclopropanation
Amination, Diethyl azodicarboxylate, ethyl 2-cyano-2-phenylacetate, 1,2-Diethyl 1-(1-cyano-2-ethoxy-2-oxo-1-phenylethyl)-1,2-hydrazinedicarboxylate, 3-[[[(1S)-2,2′-dihydroxy[1,1′-binaphthalen]-3-yl]methyl]amino]-4-[[(9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine Derivativealpha-Amination, Amination
Amination, Diethyl azodicarboxylate, Methyl 2-oxocyclopentanecarboxylate, 1,2-Diethyl 1-[(1S)-1-(methoxycarbonyl)-2-oxocyclopentyl]-1,2-hydrazinedicarboxylate, 3-[[[(1S)-2,2′-dihydroxy[1,1′-binaphthalen]-3-yl]methyl]amino]-4-[[(9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine Derivativealpha-Amination, Amination
Michael Addition, 2-hydroxy-1,4-naphthoquinone, nitroalkenes, substituted 2-hydroxy-3-(2-nitroethyl)naphthalene-1,4-dione, 3-[[[(1S)-2,2′-dihydroxy[1,1′-binaphthalen]-3-yl]methyl]amino]-4-[[(9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition
Michael Addition, nitroalkenes, 1,3-dicarbonyl compounds, nitroalkanes, 3-[[[(1S)-2,2′-dihydroxy[1,1′-binaphthalen]-3-yl]methyl]amino]-4-[[(9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition
Resolution, racemic 7′-hydroxy-2′,3′-dihydrospiro[chromane-4,1′-inden]-2-one, (R)-7′-hydroxy-2′,3′-dihydrospiro[chromane-4,1′-inden]-2-one, (8α,9R)-9-hydroxy-1-(phenylmethyl)-Cinchonanium chloride, Cinchonidine DerivativeResolution
Cascade reaction, aminooxylating compounds, nitroolefins, tetrahydro 1,2-oxazines, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeCascade reaction
Cascade reaction, N-Tosyl aminomethyl enones, trans-α-cyano-α,β-unsaturated ketones, highly substituted pyrrolidines, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione, Cinchonidine DerivativeCascade reaction
Aza-Michael Addition, bidentate aminomethyl enones, N-tosyl imines, 2,4-disubstituted imidazolidines, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione, Cinchonidine DerivativeAza-Michael, Michael Addition
Resolution, rac-BINOLs, (R)-BINOLs, N,N′-Di-tert-butylethylenediamine, Copper(I)-chloride, (8α,9R)-9-hydroxy-1-(phenylmethyl)-Cinchonanium chloride, Cinchonidine DerivativeAtropisomer synthesis, Racemic resolution, Resolution
