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Atropisomer Synthesis, 2′-((2-hydroxynaphthalen-1-yl)ethynyl)-[1,1′-biphenyl]-3,5-diol, chiral biaryltriols, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Atropisomer synthesis

Kinetic Resolution, dibenzo[b,f][1,5]diazocine-6,12(5H,11H)-dione, tert-butyl 2-(((tert-butoxycarbonyl)oxy)methyl)acrylate, planar-chiral dianthranilides, Quinine Base

Alkylation, Alkylation, Dynamic Kinetic Resolution, Kinetic resolution, Resolution

Desymmetrization, meso‐cyclic anhydrides, methanol, (1R,2S,3R,4S)-3-(methoxycarbonyl)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, Quinine Base

Desymmetrization

Atropisomer Synthesis, biaryl aldehydes, 2-amino-2,2-diphenylacetic acid, atropisomers, Quinine Base

Amination, Asymmetric Transamination, Atropisomer synthesis, Dynamic Kinetic Resolution, Resolution

Oxa-Michael Addition, (E)-7-hydroxy-5-methoxy-8-(2-methylbut-2-enoyl)-4-propyl-2H-chromen-2-one, (8R,9S)-5-methoxy-8,9-dimethyl-4-propyl-8,9-dihydro-2H,10H-pyrano[2,3-f]chromene-2,10-dione, Quinine Base

Cyclization, Cyclization, Further Cyclizations, intramolecular Oxa-Michael Addition, Michael Addition, Oxa-Michael Addition

Michael Addition, cyclic N-sulfonylimines, nitroalkenes, 3-((1R,2S)-3-nitro-1,2-diphenylpropyl)-2,3-dihydrobenzo[d]isothiazole 1,1-dioxide, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[(9R)-cinchonan-9-ylamino]-3- cyclobutene-1,2-dione, Cinchonine Derivative

Michael, Michael Addition

Aza-Michael Addition, cyclic N-sulfonylimines, 2-nitroallylic acetates, (8S,9R)-8-nitro-9,10-diphenyl-8,9-dihydro-7H-benzo[4,5]isothiazolo[2,3-a]pyridine 5,5-dioxide, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[(9R)-cinchonan-9-ylamino]-3- cyclobutene-1,2-dione, Cinchonine Derivative

Aza-Michael, Cascade reaction, Michael Addition

Spirocyclization, curcumins, 3‐olefinic oxindoles, spirocyclohexanoneoxindoles, N-(9R)-cinchonan-9-yl-N′-(4-nitrophenyl)-thiourea, Cinchonine Derivative

Spirocyclization

Atropisomer Synthesis, atropisomeric alkenes, (3-bromoprop-1-yn-1-yl)trimethylsilane, chiral 2‐arylpyrroles, (9S)-2′-[3,5-bis(1,1-dimethylethyl)phenyl]-9-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-[(3,4,5-trifluorophenyl)methyl]-cinchonanium bromide, Cinchonine Derivative

Atropisomer synthesis

Hydrogenation of Imines, Imines, trichlorosilane, (R)-N-(1-(4-chlorophenyl)ethyl)-4-methoxyaniline, N-[(9R)-6′-hydroxycinchonan-9-yl]-2-pyridinecarboxamide, Cupreidine Derivative

Hydrogenation, Hydrogenation of imines, Hydrosilylation

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