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Aza-Friedel-Crafts Alkylation, naphthols, isatin‐derived ketimines, aryl indoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Aza-Friedel-Crafts, Friedel-Crafts

Cyclization, 5,5-disubstituted cyclohexane-1,3-dione, substituted isopropyl 2-cyanoacrylate, isopropyl 2-amino-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Cyclization, Cyclization, Further Cyclizations, Michael, Michael Addition

Friedel-Crafts reaction, arylsulfonyl indoles, naphthalen-1-ol, biaryl indoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Friedel-Crafts, Friedel-Crafts alkylation

Cascade reaction, 2-(1-(4-bromophenyl)-3,3,3-trifluoro-2-oxopropylidene)-1H-indene-1,3(2H)-dione, tert-butyl (E)-2-oxo-3-(1-phenylethylidene)indoline-1-carboxylate, multiple quaternary stereocenters,N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Cascade reaction

Pictet-Spengler reaction, (E)-tert-butyl (4-((2-(4-methoxy-1H-indol-3-yl)ethyl)amino)but-2-en-1-yl) carbonate, methyl 2,2-bis(ethylthio)-5-oxopentanoate, methyl (E)-4-(2-(4-((tert-butoxycarbonyl)oxy)but-2-en-1-yl)-5-methoxy-2,3,4,9-tetrahydro-1H-1l3-pyrido[3,4-b]indol-1-yl)-2,2-bis(ethylthio)butanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Cyclization, Further Cyclizations, Pictet-Spengler Reaction

Spirocyclization, 4-isothiocyanato pyrazolones, allenones, spiro [pyrrole–pyrazolones], N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Spirocyclization

Cascade reaction, ethyl 4,4,4-trifluoro-3-oxobutanoate, (E)-(2-bromo-2-nitrovinyl)benzene, 2-trifluoromethylated dihydrofurans, 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative

Cascade reaction

Sulfa-Michael Addition, cyclohexenone, 2-methoxybenzenethiol, (S)-3-((2-methoxyphenyl)thio)cyclohexan-1-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Michael Addition, Sulfa-Michael, Sulfa-Michael Addition

Cascade reaction, 5,5-dimethylcyclohexane-1,3-dione, substituted 2-nitroacrylaldehyde, 2,3-dihydrofurans, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative

Cascade reaction

Spirocyclization, 3-isothiocyanato oxindoles, arylidene malonates, spiro compount, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Cascade reaction, Spirocyclization

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