Spirocyclization, methyl (E)-2-(1-methyl-2-oxoindolin-3-ylidene)acetate, 7-methyl-3-((2,2,2-trifluoroethyl)imino)benzo[b]thiophen-2(3H)-one, bispiro[oxindole‐pyrrolidine‐benzothiophenone]s, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeSpirocyclization Spirocyclization, unsaturated pyrrolin-4-ones, 2-mercaptoacetaldehyde, spiro-Δ2-pyrrolin-4-ones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeSpirocyclization Spirocyclization, substituted 5-methyl-4-methylene-2,4-dihydro-3H-pyrazol-3-one, substituted (E)-2-((2,2-difluoroethyl)imino)benzo[b]thiophen-3(2H)-one, CF2H-containing dispiro [benzo[b]thiophene-pyrrolidine-pyrazole]s, N-[(9R)-6′-methoxycinchonan-9-yl]-N′-[4-(trifluoromethyl)phenyl]-thiourea, Quinidine Derivative[3+2]-Cycloaddition, Cycloaddition, Spirocyclization Spirocyclization, diethyl 2-((2,2,2-trifluoroethyl)imino)malonate, substituted (E)-4-benzylidene-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, trifluoromethyl-containing spiro-pyrrolidine-pyrazolone compounds, 3-[[(9R)-6′-Methoxycinchonan-9-yl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-cyclobutene-1,2-dione, Quinidine Derivative1,3-Dipolar Cycloaddition, Cycloaddition, Spirocyclization Michael Addition, 1-Benzoyl-1,5-dihydro-5-(phenylmethyl)-2-[(phenylmethyl)thio]-4H-imidazol-4-one, 2-Benzylidene-1,3-benzodithiole 1,1,3,3-tetroxide, (5S)-1-benzoyl-1,5-dihydro-5-(phenylmethyl)-2-[(phenylmethyl)thio]-5-[(R)-phenyl(1,1,3,3-tetraoxido-2H-1,3-benzodithiol-2-yl)methyl]-4H-Imidazol-4-one, N-[3,5-Bis(trifluoromethyl)phenyl]-3-[[2-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]-5-(trifluoromethyl)benzamide, Quinine DerivativeMichael, Michael Addition intramolecular Oxa-Michael, alkoxyboronates, 1-substituted isochromanes, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivativeintramolecular Oxa-Michael Addition, Michael Addition, Oxa-Michael Addition Spirocyclization, substituted 4-methylene-2,4-dihydro-3H-pyrazol-3-one, α,β-unsaturated ketones, Spirocyclohexanonepyrazolones, 2-fluorobenzoic acid, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeMichael, Michael Addition, Spirocyclization Trifluoromethylthiolation, substituted 2,4-dihydro-3H-pyrazol-3-one, 2-((trifluoromethyl)thio)benzo[d]isothiazol-3(2H)-one 1,1-dioxide, (R)-4-(3,5-dimethoxybenzyl)-2,5-diphenyl-4-((trifluoromethyl)thio)-2,4-dihydro-3H-pyrazol-3-one, (9S)-9-hydroxy-6′-methoxy-1-[2-oxo-2-[(triphenylmethyl)amino]ethyl]-cinchonanium bromide, Quinidine DerivativeTrifluoro-methylthiolation Spirocyclization, bifunctional oxindole–chromone synthons, methyleneindolinones, bispirooxindole-based hexahydroxanthones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction, Spirocyclization Aza-Michael, para-quinone methide derivatives, α-bromohydroxamates, (S)-N-(benzyloxy)-2-bromo-N-((3,5-di-tert-butyl-4-hydroxyphenyl)(2-hydroxyphenyl)methyl)acetamide, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeAza-Michael, Michael Addition« Older EntriesNext Entries »
Spirocyclization, methyl (E)-2-(1-methyl-2-oxoindolin-3-ylidene)acetate, 7-methyl-3-((2,2,2-trifluoroethyl)imino)benzo[b]thiophen-2(3H)-one, bispiro[oxindole‐pyrrolidine‐benzothiophenone]s, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeSpirocyclization
Spirocyclization, unsaturated pyrrolin-4-ones, 2-mercaptoacetaldehyde, spiro-Δ2-pyrrolin-4-ones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeSpirocyclization
Spirocyclization, substituted 5-methyl-4-methylene-2,4-dihydro-3H-pyrazol-3-one, substituted (E)-2-((2,2-difluoroethyl)imino)benzo[b]thiophen-3(2H)-one, CF2H-containing dispiro [benzo[b]thiophene-pyrrolidine-pyrazole]s, N-[(9R)-6′-methoxycinchonan-9-yl]-N′-[4-(trifluoromethyl)phenyl]-thiourea, Quinidine Derivative[3+2]-Cycloaddition, Cycloaddition, Spirocyclization
Spirocyclization, diethyl 2-((2,2,2-trifluoroethyl)imino)malonate, substituted (E)-4-benzylidene-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, trifluoromethyl-containing spiro-pyrrolidine-pyrazolone compounds, 3-[[(9R)-6′-Methoxycinchonan-9-yl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-cyclobutene-1,2-dione, Quinidine Derivative1,3-Dipolar Cycloaddition, Cycloaddition, Spirocyclization
Michael Addition, 1-Benzoyl-1,5-dihydro-5-(phenylmethyl)-2-[(phenylmethyl)thio]-4H-imidazol-4-one, 2-Benzylidene-1,3-benzodithiole 1,1,3,3-tetroxide, (5S)-1-benzoyl-1,5-dihydro-5-(phenylmethyl)-2-[(phenylmethyl)thio]-5-[(R)-phenyl(1,1,3,3-tetraoxido-2H-1,3-benzodithiol-2-yl)methyl]-4H-Imidazol-4-one, N-[3,5-Bis(trifluoromethyl)phenyl]-3-[[2-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]-5-(trifluoromethyl)benzamide, Quinine DerivativeMichael, Michael Addition
intramolecular Oxa-Michael, alkoxyboronates, 1-substituted isochromanes, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivativeintramolecular Oxa-Michael Addition, Michael Addition, Oxa-Michael Addition
Spirocyclization, substituted 4-methylene-2,4-dihydro-3H-pyrazol-3-one, α,β-unsaturated ketones, Spirocyclohexanonepyrazolones, 2-fluorobenzoic acid, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeMichael, Michael Addition, Spirocyclization
Trifluoromethylthiolation, substituted 2,4-dihydro-3H-pyrazol-3-one, 2-((trifluoromethyl)thio)benzo[d]isothiazol-3(2H)-one 1,1-dioxide, (R)-4-(3,5-dimethoxybenzyl)-2,5-diphenyl-4-((trifluoromethyl)thio)-2,4-dihydro-3H-pyrazol-3-one, (9S)-9-hydroxy-6′-methoxy-1-[2-oxo-2-[(triphenylmethyl)amino]ethyl]-cinchonanium bromide, Quinidine DerivativeTrifluoro-methylthiolation
Spirocyclization, bifunctional oxindole–chromone synthons, methyleneindolinones, bispirooxindole-based hexahydroxanthones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction, Spirocyclization
Aza-Michael, para-quinone methide derivatives, α-bromohydroxamates, (S)-N-(benzyloxy)-2-bromo-N-((3,5-di-tert-butyl-4-hydroxyphenyl)(2-hydroxyphenyl)methyl)acetamide, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeAza-Michael, Michael Addition
