Friedel-Crafts reaction, sesamol, N-benzylisatin, (R)-1-Benzyl-3-hydroxy-3-(5-hydroxybenzo[d][1,3] dioxol-6-yl) indolin-2-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeFriedel-Crafts, Friedel-Crafts reaction Desymmetrization, 1-[1-(1,1-Dimethyl-3-buten-1-yl)-4-oxo-2,5-cyclohexadien-1-yl] 3-(1,1-dimethylethyl) propanedioate, rel-1,1-Dimethylethyl (3R,3aS,7aS)-7a-(1,1-dimethyl-3-buten-1-yl)-2,3,3a,4,5,7a-hexahydro-2,5-dioxo-3-benzofurancarboxylate, caesium carbonate, (8α,9R)-1-(9-anthracenylmethyl)-9-(2-propenyloxy)-Cinchonanium bromide, Cinchonidine DerivativeDesymmetrization Michael Addition, 1-acetylindolin-3-ones, β,γ-unsaturated α-keto esters, substituted ethyl (S)-2-oxo-4-(3-oxoindolin-2-yl)butanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition Friedel-Crafts reaction, 3,5-dimethoxylphenol, nitroolefins, substituted (R)-3,5-dimethoxy-2-(2-nitro-1-phenylethyl)phenol, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeFriedel-Crafts, Friedel-Crafts reaction Sulfa-Michael Addition, α-substituted N-acryloyloxazolidin-2-ones, thiols, C/S-substituted 3-(3-mercaptopropanoyl)oxazolidin-2-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael Addition, Sulfa-Michael, Sulfa-Michael Addition Michael Addition, 3‐Substituted Benzofuran‐2(3H)‐ones, 1,1‐Bis(phenylsulfonyl)ethylene, substituted 3-(2,2-bis(phenylsulfonyl)ethyl)benzofuran-2(3H)-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition Desymmetrization, cyclic anhydrides, cyclohexanethiol, 3-(2-(cyclohexylthio)-2-oxoethyl)-5-methylhexanoic acid, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeDesymmetrization Spirocyclization, substituted 3-(4-oxo-4,5,6,7-tetrahydrobenzofuran-3-yl)indolin-2-one, (E)-(2-nitrovinyl)benzene, spirooxindoles, (8α,9R)-10,11-dihydro-6′-methoxy-11-phenyl-cinchonan-9-ol, Quinine DerivativeCascade reaction, Spirocyclization Spirocyclization, substituted indoline-2,3-dione, substituted phenylmethanamine, nitroalkenes, substituted 4′-nitrospiro[indoline-3,2′-pyrrolidin]-2-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCascade reaction, Spirocyclization Dearomatization, 1-(3-methyl-3-tosylbut-1-yn-1-yl)naphthalen-2-ol, N-bromophthalimide, (3aR,7aR)-1-bromo-2,2,6-trimethyl-2H,7aH-benzo[a]thieno[2,3-l]xanthene 3,3-dioxide, (2S)-2-[[2-[[3,5-bis(trifluoromethyl)phenyl]amino]-4,5-dioxo-1-cyclobuten-1-yl]amino]-N-[(9S)-6′-methoxycinchonan-9-yl]-3-methyl-butanamide, Quinine DerivativeCyclization, Cyclization, Dearomatization, Further Cyclizations, Further reactions« Older EntriesNext Entries »
Friedel-Crafts reaction, sesamol, N-benzylisatin, (R)-1-Benzyl-3-hydroxy-3-(5-hydroxybenzo[d][1,3] dioxol-6-yl) indolin-2-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeFriedel-Crafts, Friedel-Crafts reaction
Desymmetrization, 1-[1-(1,1-Dimethyl-3-buten-1-yl)-4-oxo-2,5-cyclohexadien-1-yl] 3-(1,1-dimethylethyl) propanedioate, rel-1,1-Dimethylethyl (3R,3aS,7aS)-7a-(1,1-dimethyl-3-buten-1-yl)-2,3,3a,4,5,7a-hexahydro-2,5-dioxo-3-benzofurancarboxylate, caesium carbonate, (8α,9R)-1-(9-anthracenylmethyl)-9-(2-propenyloxy)-Cinchonanium bromide, Cinchonidine DerivativeDesymmetrization
Michael Addition, 1-acetylindolin-3-ones, β,γ-unsaturated α-keto esters, substituted ethyl (S)-2-oxo-4-(3-oxoindolin-2-yl)butanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition
Friedel-Crafts reaction, 3,5-dimethoxylphenol, nitroolefins, substituted (R)-3,5-dimethoxy-2-(2-nitro-1-phenylethyl)phenol, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeFriedel-Crafts, Friedel-Crafts reaction
Sulfa-Michael Addition, α-substituted N-acryloyloxazolidin-2-ones, thiols, C/S-substituted 3-(3-mercaptopropanoyl)oxazolidin-2-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael Addition, Sulfa-Michael, Sulfa-Michael Addition
Michael Addition, 3‐Substituted Benzofuran‐2(3H)‐ones, 1,1‐Bis(phenylsulfonyl)ethylene, substituted 3-(2,2-bis(phenylsulfonyl)ethyl)benzofuran-2(3H)-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition
Desymmetrization, cyclic anhydrides, cyclohexanethiol, 3-(2-(cyclohexylthio)-2-oxoethyl)-5-methylhexanoic acid, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeDesymmetrization
Spirocyclization, substituted 3-(4-oxo-4,5,6,7-tetrahydrobenzofuran-3-yl)indolin-2-one, (E)-(2-nitrovinyl)benzene, spirooxindoles, (8α,9R)-10,11-dihydro-6′-methoxy-11-phenyl-cinchonan-9-ol, Quinine DerivativeCascade reaction, Spirocyclization
Spirocyclization, substituted indoline-2,3-dione, substituted phenylmethanamine, nitroalkenes, substituted 4′-nitrospiro[indoline-3,2′-pyrrolidin]-2-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCascade reaction, Spirocyclization
Dearomatization, 1-(3-methyl-3-tosylbut-1-yn-1-yl)naphthalen-2-ol, N-bromophthalimide, (3aR,7aR)-1-bromo-2,2,6-trimethyl-2H,7aH-benzo[a]thieno[2,3-l]xanthene 3,3-dioxide, (2S)-2-[[2-[[3,5-bis(trifluoromethyl)phenyl]amino]-4,5-dioxo-1-cyclobuten-1-yl]amino]-N-[(9S)-6′-methoxycinchonan-9-yl]-3-methyl-butanamide, Quinine DerivativeCyclization, Cyclization, Dearomatization, Further Cyclizations, Further reactions
