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Cascade reaction, N-protected ethyl 2-aminobut-3-ynoate, 1-(2-hydroxyphenyl)butane-1,3-dione, tricyclic furanobenzodihydropyrans, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine Derivative

Cascade reaction

Amination, alkenes, alkyl halides, aryl sulfoximines, N-substituted aryl sulfoximines, 2-[bis(3,3′′,5,5′′-tetramethyl[1,1′:3′,1′′-terphenyl]-5′-yl)phosphino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-benzamide, Quinine Derivative

Amination

Aza-Michael Addition, 4-nitrobenzohydrazide, (E)-2,4-dichloro-1-(2-nitrovinyl)benzene, (R)-N’-(1-(2,4-dichlorophenyl)-2-nitroethyl)-4-nitrobenzohydrazide, (8α,9R)-6′-methoxy-cinchonan-9-ol 3,4-dimethoxybenzoate, Quinine Derivative

Aza-Michael, Michael Addition

Desymmetrization, unprotected sulfonimidamides, 2,2,2-trifluoroethyl 2,2,2-trifluoroacetate, enantioenriched sulfonimidamides, (8α,9R)-6′-methoxy-Cinchonan-9-ol-9-(P,P-dicyclohexylphosphinate), Quinine Derivative

Desymmetrization

Mannich reaction, α-aminomaleimides, N-Boc imines, β-substituted α-aminomaleimides, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-N′-phenylurea, Quinine Derivative

Mannich, Mannich

Cyclization, α-bromonitroalkenes, 1,3-dicarbonyl compounds, 2,3-dihydrofurans, 3-[(1,1-dimethylethyl)amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative

Cascade reaction, Cyclization, Michael, Michael Addition

Mannich reaction, α-fluoroindanones, isatin-derived N-Boc-ketimines, 3-substituted 3-amino-2-oxindoles, 9-hydroxy-1-[(4-iodophenyl)methyl]-6′-methoxy-(8α,9R)-cinchonanium bromide, Quinine Derivative

Mannich, Mannich

Fluorination, (R)-2-methyl-N-((S,Z)-2-methyl-1-phenylbutylidene)propane-2-sulfinamide, (R)-N-((R,E)-2-fluoro-2-methyl-1-phenylbutylidene)-2-methylpropane-2-sulfinamide, (8α,9R)-1-fluoro-9-hydroxy-6′-methoxy-Cinchonanium salt with N-(phenylsulfonyl)benzenesulfonamide, Quinine Derivative

Fluorination, Fluorination

Mannich reaction, N-unprotected trifluoromethyl ketimines, diketones, N-unprotected α-tetrasubstituted amino acid esters, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Michael, Michael Addition

Resolution, 3-phenyloxetan-2-one, OH-donors, (S)-3-hydroxy-2-phenylpropanoic acid, 9-hydroxy-6′-methoxy-1-(phenylmethyl)-(9S)-cinchonanium chloride, Quinidine Derivative

Dynamic Kinetic Resolution, Resolution

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