Cyclization, (E)-4-(2-ethynylphenyl)but-3-en-2-one, 1-benzyl-1H-pyrrole-2,5-dione, (3aR,7S,7aS)-2-benzyl-7-(2-ethynylphenyl)tetrahydro-1H-isoindole-1,3,5(2H,4H)-trione, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeCyclization, Cyclization, Further Cyclizations Spirocyclization, substituted 3-iminoindolin-2-one, substituted 4-(prop-2-yn-1-yl)-2,4-dihydro-3H-pyrazol-3-one, bispiro[oxindole-pyrrolidine-pyrazolone] derivatives, 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMannich, Mannich, Spirocyclization Atropisomer Synthesis, 1-((2-(9H-carbazol-9-yl)phenyl)ethynyl)naphthalen-2-ol, N-bromosuccinimide, azepine skeletons, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAtropisomer synthesis, Bromination, Cyclization, Cyclization, Further Cyclizations Atropisomer Synthesis, tert-butyl 7-bromo-1-methyl-6-oxoindolo[1,2-a]quinoxaline-5(6H)-carboxylate, ethyl 2-isocyanoacetate, lactam-bridged N-arylindoles, 2-(diphenylphosphino)-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-benzamide, Quinine DerivativeAtropisomer synthesis Cross-Coupling, alkyl bromides, 2-(4-methoxyphenyl)-1,3,4-oxadiazole, (R)-2-(4-methoxyphenyl)-5-(1-phenylpropyl)-1,3,4-oxadiazole, copper catalyst, 2-(di-9-phenanthrenylphosphino)-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-benzamide, Quinine DerivativeCross Coupling Mannich reaction, β,γ-Alkynyl-α-imino esters, 1,3-diones, substituted ethyl (R)-4-amino-5-oxo-5,6,7,8-tetrahydro-4H-chromene-4-carboxylate, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative[3+3]-Annulation, Cyclization, Further Cyclizations, Mannich, Mannich Atropisomer Synthesis, 1,2-diarylethynes, N-iodosuccinimide, atropisomeric heterobiaryls, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAtropisomer synthesis Atropisomer Synthesis, substituted 1-ethynylnaphthalen-2-ol, substituted oxazolinone, atropisomers, 3,4-Bis[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeAlkylation, Alkylation, Atropisomer synthesis Michael Addition, tert-butyl (Z)-2-cyano-2-(5-phenyl-1,2,4-triazin-3(2H)-ylidene)acetate, 4-hydroxy-4-methylpent-1-en-3-one, 3-Alkyl-1,2,4-triazines, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition Amination, substituted 2-phenylhepta-5,6-dienal, di-tert-butyl (E)-diazene-1,2-dicarboxylate, polysubstituted hexahydropyridazines, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine Derivativealpha-Amination, Amination« Older EntriesNext Entries »
Cyclization, (E)-4-(2-ethynylphenyl)but-3-en-2-one, 1-benzyl-1H-pyrrole-2,5-dione, (3aR,7S,7aS)-2-benzyl-7-(2-ethynylphenyl)tetrahydro-1H-isoindole-1,3,5(2H,4H)-trione, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeCyclization, Cyclization, Further Cyclizations
Spirocyclization, substituted 3-iminoindolin-2-one, substituted 4-(prop-2-yn-1-yl)-2,4-dihydro-3H-pyrazol-3-one, bispiro[oxindole-pyrrolidine-pyrazolone] derivatives, 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMannich, Mannich, Spirocyclization
Atropisomer Synthesis, 1-((2-(9H-carbazol-9-yl)phenyl)ethynyl)naphthalen-2-ol, N-bromosuccinimide, azepine skeletons, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAtropisomer synthesis, Bromination, Cyclization, Cyclization, Further Cyclizations
Atropisomer Synthesis, tert-butyl 7-bromo-1-methyl-6-oxoindolo[1,2-a]quinoxaline-5(6H)-carboxylate, ethyl 2-isocyanoacetate, lactam-bridged N-arylindoles, 2-(diphenylphosphino)-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-benzamide, Quinine DerivativeAtropisomer synthesis
Cross-Coupling, alkyl bromides, 2-(4-methoxyphenyl)-1,3,4-oxadiazole, (R)-2-(4-methoxyphenyl)-5-(1-phenylpropyl)-1,3,4-oxadiazole, copper catalyst, 2-(di-9-phenanthrenylphosphino)-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-benzamide, Quinine DerivativeCross Coupling
Mannich reaction, β,γ-Alkynyl-α-imino esters, 1,3-diones, substituted ethyl (R)-4-amino-5-oxo-5,6,7,8-tetrahydro-4H-chromene-4-carboxylate, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative[3+3]-Annulation, Cyclization, Further Cyclizations, Mannich, Mannich
Atropisomer Synthesis, 1,2-diarylethynes, N-iodosuccinimide, atropisomeric heterobiaryls, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAtropisomer synthesis
Atropisomer Synthesis, substituted 1-ethynylnaphthalen-2-ol, substituted oxazolinone, atropisomers, 3,4-Bis[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeAlkylation, Alkylation, Atropisomer synthesis
Michael Addition, tert-butyl (Z)-2-cyano-2-(5-phenyl-1,2,4-triazin-3(2H)-ylidene)acetate, 4-hydroxy-4-methylpent-1-en-3-one, 3-Alkyl-1,2,4-triazines, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition
Amination, substituted 2-phenylhepta-5,6-dienal, di-tert-butyl (E)-diazene-1,2-dicarboxylate, polysubstituted hexahydropyridazines, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine Derivativealpha-Amination, Amination
