Oxa-Michael, α,β-unsaturated carbonyl compound, 1,1‐disubstituted‐1,3‐dihydroisobenzofurans, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine Derivativeintramolecular Oxa-Michael Addition, Michael Addition, Oxa-Michael Addition Michael Addition, 2‐oxindole‐3‐carboxylate esters, 2‐phthalimido acrylates, substituted 2-oxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition [3+2] Annulation, cyclopropanes, nitrosoarenes, isoxazolidines, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine Derivative[3+2] Annulation, Cyclization, Further Cyclizations Amination, α-keto esters, arylmethanamines, α-Imino esters, (8α,9R)-9-[(6-chloro-2,5-diphenyl-4-pyrimidinyl)oxy]-1-[[2′-(1,1-dimethylethoxy)-3,3′′,4,4′′,5,5′′-hexamethoxy[1,1′:3′,3′′-terphenyl]-5′-yl]methyl]-6′-hydroxy-cinchonanium inner salt, Cupreine DerivativeAmination, Asymmetric Transamination, Isomerization Mannich reaction, ketimines, TosMIC, ((4S,5S)-5-methyl-5-phenyl-4-tosyl-4,5-dihydro-1H-imidazol-1-yl)diphenylphosphine oxide, silver catalyst, N-[(8α,9S)-10,11-dihydro-6′-methoxycinchonan -9-yl]-2-(diphenylphosphino)-benzamide, Dihydroquinine derivativeMannich, Mannich Resolution, 1-hydroxy-2,5-diphenylphospholane 1-oxide, (2S,5S)-1-hydroxy-2,5-diphenylphospholane 1-oxide, Quinine BaseResolution Alkylation, phosphinic acids, iodomethane, methyl (S)-(naphthalen-1-ylmethyl)(phenyl)phosphinate, (8α,9R)1-[(3,5-dimethylphenyl)methyl]-9-hydroxy-cinchonanium bromide, Cinchonidine DerivativeAlkylation, Alkylation Cascade Reaction, N-substituted Imines, substituted 3-methylenedihydrofuran-2(3H)-one, chiral amines, (8α,9R)-9-[(6-chloro-2,5-diphenyl-4-pyrimidinyl)oxy]-1-[[2′-(1,1-dimethylethoxy)-3,3′′,4,4′′,5,5′′-hexamethoxy[1,1′:3′,1′′-terphenyl]-5′-yl]methyl]-cinchonanium bromide, Cinchonidine DerivativeCascade reaction Mannich reaction, isatin-derived ketimines, cyclic N-sulfonyl ketimines, substituted (R)-3-amino-3-((2,2-dioxidobenzo[e][1,2,3]oxathiazin-4-yl)methyl)indolin-2-one, N-[(1S,2S)-2-[[[(8α,9S)-cinchonan-9-ylamino]thioxomethyl]amino]-1,2-diphenylethyl]-4-methyl-benzenesulfonamide, Cinchonidine DerivativeMannich, Mannich Atropisomer Synthesis, indene-dienes, isochromane-1,3-dione, atropisomeric isoquinolones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeAtropisomer synthesis, Cascade reaction« Older EntriesNext Entries »
Oxa-Michael, α,β-unsaturated carbonyl compound, 1,1‐disubstituted‐1,3‐dihydroisobenzofurans, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine Derivativeintramolecular Oxa-Michael Addition, Michael Addition, Oxa-Michael Addition
Michael Addition, 2‐oxindole‐3‐carboxylate esters, 2‐phthalimido acrylates, substituted 2-oxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition
[3+2] Annulation, cyclopropanes, nitrosoarenes, isoxazolidines, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine Derivative[3+2] Annulation, Cyclization, Further Cyclizations
Amination, α-keto esters, arylmethanamines, α-Imino esters, (8α,9R)-9-[(6-chloro-2,5-diphenyl-4-pyrimidinyl)oxy]-1-[[2′-(1,1-dimethylethoxy)-3,3′′,4,4′′,5,5′′-hexamethoxy[1,1′:3′,3′′-terphenyl]-5′-yl]methyl]-6′-hydroxy-cinchonanium inner salt, Cupreine DerivativeAmination, Asymmetric Transamination, Isomerization
Mannich reaction, ketimines, TosMIC, ((4S,5S)-5-methyl-5-phenyl-4-tosyl-4,5-dihydro-1H-imidazol-1-yl)diphenylphosphine oxide, silver catalyst, N-[(8α,9S)-10,11-dihydro-6′-methoxycinchonan -9-yl]-2-(diphenylphosphino)-benzamide, Dihydroquinine derivativeMannich, Mannich
Resolution, 1-hydroxy-2,5-diphenylphospholane 1-oxide, (2S,5S)-1-hydroxy-2,5-diphenylphospholane 1-oxide, Quinine BaseResolution
Alkylation, phosphinic acids, iodomethane, methyl (S)-(naphthalen-1-ylmethyl)(phenyl)phosphinate, (8α,9R)1-[(3,5-dimethylphenyl)methyl]-9-hydroxy-cinchonanium bromide, Cinchonidine DerivativeAlkylation, Alkylation
Cascade Reaction, N-substituted Imines, substituted 3-methylenedihydrofuran-2(3H)-one, chiral amines, (8α,9R)-9-[(6-chloro-2,5-diphenyl-4-pyrimidinyl)oxy]-1-[[2′-(1,1-dimethylethoxy)-3,3′′,4,4′′,5,5′′-hexamethoxy[1,1′:3′,1′′-terphenyl]-5′-yl]methyl]-cinchonanium bromide, Cinchonidine DerivativeCascade reaction
Mannich reaction, isatin-derived ketimines, cyclic N-sulfonyl ketimines, substituted (R)-3-amino-3-((2,2-dioxidobenzo[e][1,2,3]oxathiazin-4-yl)methyl)indolin-2-one, N-[(1S,2S)-2-[[[(8α,9S)-cinchonan-9-ylamino]thioxomethyl]amino]-1,2-diphenylethyl]-4-methyl-benzenesulfonamide, Cinchonidine DerivativeMannich, Mannich
Atropisomer Synthesis, indene-dienes, isochromane-1,3-dione, atropisomeric isoquinolones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeAtropisomer synthesis, Cascade reaction
