Spirocyclization, 3-(2-methylallyl)cyclohex-2-en-1-one, ethyl 2-oxo-2H-chromene-3-carboxylate, spiro-fused coumarins, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine Derivative[4+2]-Cycloaddition, Cycloaddition, Diels-Alder reaction, Spirocyclization Alkylation, N-(arylthio)benzamide, toluene, sulfilimines, copper catalyst, N-[(S)-[(1S,2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]oct-2-yl](6-methoxy-4-quinolinyl)methyl]-8-quinolinesulfonamide, Quinine DerivativeAlkylation, S-Alkylation Thiolation, pyrazolone ketimines, thiols, thiolated pyrazolone ketimines, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9R)-6′-methoxy-9-(phenylmethoxy)cinchonan-2′-yl]-thiourea, Quinine DerivativeAddition, Further reactions, Thiolation Atropisomer Synthesis, 2-hydroxynaphthalene-1,4-dione, 7-bromo-2-oxo-2H-chromene-3-carboxylic acid, naphthocoumarin atropisomers, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAtropisomer synthesis Desymmetrization, sulfondiimines, 2,2,2-trifluoroethyl 2,2,2-trifluoroacetate, 2,2,2-trifluoro-N-(imino-sulfonylidene)acetamides, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-P,P-diphenyl-phosphinic amide, Quinine DerivativeDesymmetrization Reduction, ketones, secondary alcohols, manganese catalyst, (R)-1-(quinolin-4-yl)-N-(thiophen-2-ylmethyl)-1-((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methanamine, Cinchonine DerivativeHydrogenation, Hydrogenation of ketones, Reduction Atropisomer Synthesis, substituted 5-phenyl-1H-pyrrole-3-carboxylic acid, atropisomer, Quinine BaseAtropisomer synthesis, Racemic resolution, Resolution Spirocyclization, 3-Isothiocyanato oxindoles, (E)-5-(2-(substituted)vinyl)-3-methyl-4-nitroisoxazole, 3,3′-pyrrolidonyl spirooxindoles, Quinine BaseSpirocyclization Cascade reaction, 4-(2-(methylthio)ethyl)-2-phenyloxazol-5(4H)-one, (E)-3-(2-hydroxyphenyl)-1-phenylprop-2-en-1-one, 3,4‐dihydrocoumarins, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCascade reaction Carbene Transfer, substituted 3-diazo-4-methylenepyrrolidine-2,5-dione, α,β-unsaturated carbonyl compound, substituted (S)-3-(1,3-dioxo-2,3-dihydroindeno[1,2-c]pyrrol-3a(1H)-yl)propanal, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCarbene Transfer, Further reactions« Older EntriesNext Entries »
Spirocyclization, 3-(2-methylallyl)cyclohex-2-en-1-one, ethyl 2-oxo-2H-chromene-3-carboxylate, spiro-fused coumarins, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine Derivative[4+2]-Cycloaddition, Cycloaddition, Diels-Alder reaction, Spirocyclization
Alkylation, N-(arylthio)benzamide, toluene, sulfilimines, copper catalyst, N-[(S)-[(1S,2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]oct-2-yl](6-methoxy-4-quinolinyl)methyl]-8-quinolinesulfonamide, Quinine DerivativeAlkylation, S-Alkylation
Thiolation, pyrazolone ketimines, thiols, thiolated pyrazolone ketimines, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9R)-6′-methoxy-9-(phenylmethoxy)cinchonan-2′-yl]-thiourea, Quinine DerivativeAddition, Further reactions, Thiolation
Atropisomer Synthesis, 2-hydroxynaphthalene-1,4-dione, 7-bromo-2-oxo-2H-chromene-3-carboxylic acid, naphthocoumarin atropisomers, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAtropisomer synthesis
Desymmetrization, sulfondiimines, 2,2,2-trifluoroethyl 2,2,2-trifluoroacetate, 2,2,2-trifluoro-N-(imino-sulfonylidene)acetamides, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-P,P-diphenyl-phosphinic amide, Quinine DerivativeDesymmetrization
Reduction, ketones, secondary alcohols, manganese catalyst, (R)-1-(quinolin-4-yl)-N-(thiophen-2-ylmethyl)-1-((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methanamine, Cinchonine DerivativeHydrogenation, Hydrogenation of ketones, Reduction
Atropisomer Synthesis, substituted 5-phenyl-1H-pyrrole-3-carboxylic acid, atropisomer, Quinine BaseAtropisomer synthesis, Racemic resolution, Resolution
Spirocyclization, 3-Isothiocyanato oxindoles, (E)-5-(2-(substituted)vinyl)-3-methyl-4-nitroisoxazole, 3,3′-pyrrolidonyl spirooxindoles, Quinine BaseSpirocyclization
Cascade reaction, 4-(2-(methylthio)ethyl)-2-phenyloxazol-5(4H)-one, (E)-3-(2-hydroxyphenyl)-1-phenylprop-2-en-1-one, 3,4‐dihydrocoumarins, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCascade reaction
Carbene Transfer, substituted 3-diazo-4-methylenepyrrolidine-2,5-dione, α,β-unsaturated carbonyl compound, substituted (S)-3-(1,3-dioxo-2,3-dihydroindeno[1,2-c]pyrrol-3a(1H)-yl)propanal, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCarbene Transfer, Further reactions