Cyclization, (E)-N-(4-methoxybenzylidene)-4-methylbenzenesulfonamide, isocyanatomalonate diester, 2-imidazolidinones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCyclization, Cyclization, Further Cyclizations, Mannich, Mannich Michael Addition, pyrazoleamides, β-phthalimidonitroethene, 2-((2R,3S)-1-nitro-4-oxo-3-phenyl-4-(1H-pyrazol-1-yl)butan-2-yl)isoindoline-1,3-dione, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition Spirocyclization, (E)-1,5-dimethyl-3-(2-oxo-2-phenylethylidene)indolin-2-one, 3-isothiocyanato-1-methylindolin-2-one, bispirooxindoles, N-[(1R)-2′-amino[1,1′-binaphthalen]-2-yl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]-thiourea, Quinine DerivativeMichael, Michael Addition, Spirocyclization Strecker Reaction, cyclic (Z)-aldimines, ethyl carbonocyanidate, (S)-spiro[cyclohexane-1,3′-indoline]-2′-carbonitrile, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeStrecker Michael Addition, 2-imino-2H-chromene-3-carbonitrile, diisopropyl malonate, 2-amino-3-nitrile-chromenes, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition Aza-Friedel-Crafts Alkylation, naphthols, isatin‐derived ketimines, aryl indoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAza-Friedel-Crafts, Friedel-Crafts Cyclization, 5,5-disubstituted cyclohexane-1,3-dione, substituted isopropyl 2-cyanoacrylate, isopropyl 2-amino-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCyclization, Cyclization, Further Cyclizations, Michael, Michael Addition Friedel-Crafts reaction, arylsulfonyl indoles, naphthalen-1-ol, biaryl indoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeFriedel-Crafts, Friedel-Crafts alkylation Cascade reaction, 2-(1-(4-bromophenyl)-3,3,3-trifluoro-2-oxopropylidene)-1H-indene-1,3(2H)-dione, tert-butyl (E)-2-oxo-3-(1-phenylethylidene)indoline-1-carboxylate, multiple quaternary stereocenters,N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction Pictet-Spengler reaction, (E)-tert-butyl (4-((2-(4-methoxy-1H-indol-3-yl)ethyl)amino)but-2-en-1-yl) carbonate, methyl 2,2-bis(ethylthio)-5-oxopentanoate, methyl (E)-4-(2-(4-((tert-butoxycarbonyl)oxy)but-2-en-1-yl)-5-methoxy-2,3,4,9-tetrahydro-1H-1l3-pyrido[3,4-b]indol-1-yl)-2,2-bis(ethylthio)butanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCyclization, Further Cyclizations, Pictet-Spengler Reaction« Older EntriesNext Entries »
Cyclization, (E)-N-(4-methoxybenzylidene)-4-methylbenzenesulfonamide, isocyanatomalonate diester, 2-imidazolidinones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCyclization, Cyclization, Further Cyclizations, Mannich, Mannich
Michael Addition, pyrazoleamides, β-phthalimidonitroethene, 2-((2R,3S)-1-nitro-4-oxo-3-phenyl-4-(1H-pyrazol-1-yl)butan-2-yl)isoindoline-1,3-dione, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition
Spirocyclization, (E)-1,5-dimethyl-3-(2-oxo-2-phenylethylidene)indolin-2-one, 3-isothiocyanato-1-methylindolin-2-one, bispirooxindoles, N-[(1R)-2′-amino[1,1′-binaphthalen]-2-yl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]-thiourea, Quinine DerivativeMichael, Michael Addition, Spirocyclization
Strecker Reaction, cyclic (Z)-aldimines, ethyl carbonocyanidate, (S)-spiro[cyclohexane-1,3′-indoline]-2′-carbonitrile, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeStrecker
Michael Addition, 2-imino-2H-chromene-3-carbonitrile, diisopropyl malonate, 2-amino-3-nitrile-chromenes, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition
Aza-Friedel-Crafts Alkylation, naphthols, isatin‐derived ketimines, aryl indoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAza-Friedel-Crafts, Friedel-Crafts
Cyclization, 5,5-disubstituted cyclohexane-1,3-dione, substituted isopropyl 2-cyanoacrylate, isopropyl 2-amino-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCyclization, Cyclization, Further Cyclizations, Michael, Michael Addition
Friedel-Crafts reaction, arylsulfonyl indoles, naphthalen-1-ol, biaryl indoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeFriedel-Crafts, Friedel-Crafts alkylation
Cascade reaction, 2-(1-(4-bromophenyl)-3,3,3-trifluoro-2-oxopropylidene)-1H-indene-1,3(2H)-dione, tert-butyl (E)-2-oxo-3-(1-phenylethylidene)indoline-1-carboxylate, multiple quaternary stereocenters,N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction
Pictet-Spengler reaction, (E)-tert-butyl (4-((2-(4-methoxy-1H-indol-3-yl)ethyl)amino)but-2-en-1-yl) carbonate, methyl 2,2-bis(ethylthio)-5-oxopentanoate, methyl (E)-4-(2-(4-((tert-butoxycarbonyl)oxy)but-2-en-1-yl)-5-methoxy-2,3,4,9-tetrahydro-1H-1l3-pyrido[3,4-b]indol-1-yl)-2,2-bis(ethylthio)butanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCyclization, Further Cyclizations, Pictet-Spengler Reaction
