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Atropisomer Synthesis, 1-(3,3-dimethylbut-1-yn-1-yl)naphthalen-2-ol, 4-methylbenzenethiol, (E)-1-(3,3-dimethyl-1-(p-tolylthio)but-1-en-1-yl)naphthalen-2-ol, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine Derivative

Atropisomer synthesis

[4+2] Cycloaddition, 1-azaaurones, deconjugated butenolides, substituted 4,5-dihydropyrano[3,2-b]indol-2(3H)-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative

[4+2]-Cycloaddition, Cycloaddition

Cyclization, arylalcohols, deconjugated butenolides, 2-chromanones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative

Addition, Cyclization, Cyclization, Further Cyclizations

Michael Addition, cyclic ketones, (ethene-1,1-diyldisulfonyl)dibenzene, α‐branched ketone dienolates, 3-[(1,1-dimethylethyl)amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative

Michael, Michael Addition

Cyclization, vinylogous carbonyl enolates, substituted 2-nitroprop-2-en-1-ol, carbocycles, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative

Alkylation, alpha-Alkylation, Cyclization, Cyclization, Further Cyclizations

Cyclization, β,γ-unsaturated ketones, nitroalkenes, carbocycles, 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine Derivative

Addition, Cyclization, Cyclization, Further Cyclizations

Mukaiyama-Michael Reaction, substituted (E)-(buta-1,3-dien-1-yloxy)trimethylsilane, substituted diisopropyl acryloylphosphonate, substituted benzyl (E)-4-formylhex-4-enoate, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative

Further reactions, Michael, Michael Addition, Mukaiyama-Michael

Cascade reaction, 3-nitro-2 H-chromenes, acyclic enones, substituted 10a-nitro-1,4,4a,9,10,10a-hexahydrophenanthren-3(2H)-one, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine Derivative

Cascade reaction, Cyclization, Cyclization, Further Cyclizations

Atropisomer Synthesis, substituted 1,4-diethynylnaphthalene-2,3-diol, N/S-substituted sulfonyl(phenyl)methanamine, 1,4-distyrene-2,3-naphthalenediols, 3,4-Bis[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine Derivative

Atropisomer synthesis

Atropisomer Synthesis, 1,3-dimethyl-5-tosylbenzo[k]phenanthridin-6(5H)-one, phenylmethanol, biaryl amino acids, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative

Atropisomer synthesis

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