Oxa-Michael Addition, (E)-7-hydroxy-5-methoxy-8-(2-methylbut-2-enoyl)-4-propyl-2H-chromen-2-one, (8R,9S)-5-methoxy-8,9-dimethyl-4-propyl-8,9-dihydro-2H,10H-pyrano[2,3-f]chromene-2,10-dione, Quinine BaseCyclization, Cyclization, Further Cyclizations, intramolecular Oxa-Michael Addition, Michael Addition, Oxa-Michael Addition Michael Addition, cyclic N-sulfonylimines, nitroalkenes, 3-((1R,2S)-3-nitro-1,2-diphenylpropyl)-2,3-dihydrobenzo[d]isothiazole 1,1-dioxide, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[(9R)-cinchonan-9-ylamino]-3- cyclobutene-1,2-dione, Cinchonine DerivativeMichael, Michael Addition Aza-Michael Addition, cyclic N-sulfonylimines, 2-nitroallylic acetates, (8S,9R)-8-nitro-9,10-diphenyl-8,9-dihydro-7H-benzo[4,5]isothiazolo[2,3-a]pyridine 5,5-dioxide, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[(9R)-cinchonan-9-ylamino]-3- cyclobutene-1,2-dione, Cinchonine DerivativeAza-Michael, Cascade reaction, Michael Addition Spirocyclization, curcumins, 3‐olefinic oxindoles, spirocyclohexanoneoxindoles, N-(9R)-cinchonan-9-yl-N′-(4-nitrophenyl)-thiourea, Cinchonine DerivativeSpirocyclization Atropisomer Synthesis, atropisomeric alkenes, (3-bromoprop-1-yn-1-yl)trimethylsilane, chiral 2‐arylpyrroles, (9S)-2′-[3,5-bis(1,1-dimethylethyl)phenyl]-9-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-[(3,4,5-trifluorophenyl)methyl]-cinchonanium bromide, Cinchonine DerivativeAtropisomer synthesis Hydrogenation of Imines, Imines, trichlorosilane, (R)-N-(1-(4-chlorophenyl)ethyl)-4-methoxyaniline, N-[(9R)-6′-hydroxycinchonan-9-yl]-2-pyridinecarboxamide, Cupreidine DerivativeHydrogenation, Hydrogenation of imines, Hydrosilylation Michael Addition, (E)-2-(2-nitrovinyl)furan, dimethyl malonate, dimethyl (R)-2-(1-(furan-2-yl)-2-nitroethyl)malonate, (9S)-(9′′S)-(9′′′′S)-9,9′′,9′′′′-[1,3,5-benzenetriyltris(methyleneoxy)]tris-cinchonan-6′-ol, Cupreidine DerivativeMichael, Michael Addition Spirocyclization, oxindoles, (E)-(2-nitrovinyl)benzene, spirooxindoles, (9S)-9-(9-anthracenylmethoxy)-cinchonan-6′-ol, Cupreidine DerivativeCascade reaction, Spirocyclization Aza-Michael Addition, 2-aminochalcones, 5-alkenyl-thiazolones, substituted (2R,10bR)-6-tosyl-1,2,3,5,6,10b-hexahydro-4H-2,4a-epithiobenzo[c][2,7]naphthyridin-4-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAza-Michael, Cyclization, Cyclization, Further Cyclizations, Mannich, Mannich, Michael Addition Aza-Michael Addition, substituted 3-hydroxy-3-(trifluoromethyl)-2,3-dihydrobenzo[d]isothiazole 1,1-dioxide, substituted 4-hydroxycyclohexa-2,5-dien-1-one, fluoroalkylated N,O-ketals, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAza-Michael, Desymmetrization, Michael Addition« Older EntriesNext Entries »
Oxa-Michael Addition, (E)-7-hydroxy-5-methoxy-8-(2-methylbut-2-enoyl)-4-propyl-2H-chromen-2-one, (8R,9S)-5-methoxy-8,9-dimethyl-4-propyl-8,9-dihydro-2H,10H-pyrano[2,3-f]chromene-2,10-dione, Quinine BaseCyclization, Cyclization, Further Cyclizations, intramolecular Oxa-Michael Addition, Michael Addition, Oxa-Michael Addition
Michael Addition, cyclic N-sulfonylimines, nitroalkenes, 3-((1R,2S)-3-nitro-1,2-diphenylpropyl)-2,3-dihydrobenzo[d]isothiazole 1,1-dioxide, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[(9R)-cinchonan-9-ylamino]-3- cyclobutene-1,2-dione, Cinchonine DerivativeMichael, Michael Addition
Aza-Michael Addition, cyclic N-sulfonylimines, 2-nitroallylic acetates, (8S,9R)-8-nitro-9,10-diphenyl-8,9-dihydro-7H-benzo[4,5]isothiazolo[2,3-a]pyridine 5,5-dioxide, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[(9R)-cinchonan-9-ylamino]-3- cyclobutene-1,2-dione, Cinchonine DerivativeAza-Michael, Cascade reaction, Michael Addition
Spirocyclization, curcumins, 3‐olefinic oxindoles, spirocyclohexanoneoxindoles, N-(9R)-cinchonan-9-yl-N′-(4-nitrophenyl)-thiourea, Cinchonine DerivativeSpirocyclization
Atropisomer Synthesis, atropisomeric alkenes, (3-bromoprop-1-yn-1-yl)trimethylsilane, chiral 2‐arylpyrroles, (9S)-2′-[3,5-bis(1,1-dimethylethyl)phenyl]-9-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-[(3,4,5-trifluorophenyl)methyl]-cinchonanium bromide, Cinchonine DerivativeAtropisomer synthesis
Hydrogenation of Imines, Imines, trichlorosilane, (R)-N-(1-(4-chlorophenyl)ethyl)-4-methoxyaniline, N-[(9R)-6′-hydroxycinchonan-9-yl]-2-pyridinecarboxamide, Cupreidine DerivativeHydrogenation, Hydrogenation of imines, Hydrosilylation
Michael Addition, (E)-2-(2-nitrovinyl)furan, dimethyl malonate, dimethyl (R)-2-(1-(furan-2-yl)-2-nitroethyl)malonate, (9S)-(9′′S)-(9′′′′S)-9,9′′,9′′′′-[1,3,5-benzenetriyltris(methyleneoxy)]tris-cinchonan-6′-ol, Cupreidine DerivativeMichael, Michael Addition
Spirocyclization, oxindoles, (E)-(2-nitrovinyl)benzene, spirooxindoles, (9S)-9-(9-anthracenylmethoxy)-cinchonan-6′-ol, Cupreidine DerivativeCascade reaction, Spirocyclization
Aza-Michael Addition, 2-aminochalcones, 5-alkenyl-thiazolones, substituted (2R,10bR)-6-tosyl-1,2,3,5,6,10b-hexahydro-4H-2,4a-epithiobenzo[c][2,7]naphthyridin-4-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAza-Michael, Cyclization, Cyclization, Further Cyclizations, Mannich, Mannich, Michael Addition
Aza-Michael Addition, substituted 3-hydroxy-3-(trifluoromethyl)-2,3-dihydrobenzo[d]isothiazole 1,1-dioxide, substituted 4-hydroxycyclohexa-2,5-dien-1-one, fluoroalkylated N,O-ketals, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAza-Michael, Desymmetrization, Michael Addition
