Michael Addition, chalcones, nitromethane, 1,3-disubstituted 4-nitrobutan-1-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeMichael, Michael Addition Epoxidation, ((chloromethyl)sulfonyl)benzene, aldehydes, (2R)-substituted (3R)-3-(phenylsulfonyl)oxirane, (9S)-9-hydroxy-6′-methoxy-1-[(2,3,4-trifluorophenyl)methyl]-cinchonanium bromide, Quinidine DerivativeEpoxidation Friedel-Crafts, naphthalen-1-ol, tert-butyl (Z)-(1-benzyl-2-oxoindolin-3-ylidene)carbamate, tert-butyl (R)-(1-benzyl-3-(1-hydroxynaphthalen-2-yl)-2-oxoindolin-3-yl)carbamate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeFriedel-Crafts, Friedel-Crafts alkylation Cyclization, substituted (E)-2-acetylbut-2-enenitrile, cyclohexanone, 2,4-disubstituted (4R,4aS,8aR)-8a-hydroxy-4a,5,6,7,8,8a-hexahydro-4H-chromene-3-carbonitrile, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeCyclization, Cyclization, Further Cyclizations, Michael Addition [4+2]-Cycloaddition, beta-substituted cyclic enones, polyconjugated malononitriles, substituted (1R,3S,4R)-1-methyl-5-oxo-3-((E)-prop-1-en-1-yl)bicyclo[2.2.2]octane-2,2-dicarbonitrile, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine Derivative[4+2]-Cycloaddition, Cycloaddition, Diels-Alder reaction Michael Addition, isatylidine malononitriles, methylketones, substituted (R)-2-(2-oxo-3-(2-oxopropyl)indolin-3-yl)malononitrile, 1,1′-Binaphthyl-2,2′-diyl hydrogen phosphate, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeMichael, Michael Addition Sulfenylation, ethyl 1-benzyl-4-(4-chlorobenzyl)-2-methyl-5-oxo-4,5-dihydro-1H-pyrrole-3-carboxylate, 1-(phenylthio)pyrrolidine-2,5-dione, alpha‐sulfenylated carbonyl compounds, (9S)-(9′′S)-9,9′′-[1,4-phthalazinediylbis(oxy)]bis[6′-methoxy-cinchonan, Quinidine DerivativeSulfenylation Nitro-Mannich, substituted tert-butyl ((phenylsulfonyl)methyl)carbamate, nitroalkanes, (1R,2S)-1,2-disubstituted tert-butyl (2-nitroethyl)carbamate, (9R)-9-[[[[3,5-bis(trifluoromethyl)phenyl]amino]carbonyl]amino]-6′-methoxy-1-(phenylmethyl)-cinchonanium bromide, Quinidine DerivativeMannich, Nitro-Mannich Addition, aldehydes, diethylzinc, (R)-1-substituted propan-1-ol, N-[(9R)-6′-methoxycinchonan-9-yl]-P,P- diphenyl-phosphinic amide, Quinidine DerivativeAddition Spirocyclization, substituted (E)-6-(4-hydroxyphenyl)hex-3-en-2-one, cyclohexadienone containing hindered spirocyclic ethers, 3-[[(9R)-6′-methoxycinchonan-9-yl]amino]-4-[[(1R)-1-phenylethyl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeDearomatization, Further reactions, Michael Addition, Oxa-Michael Addition, Spirocyclization« Older EntriesNext Entries »
Michael Addition, chalcones, nitromethane, 1,3-disubstituted 4-nitrobutan-1-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeMichael, Michael Addition
Epoxidation, ((chloromethyl)sulfonyl)benzene, aldehydes, (2R)-substituted (3R)-3-(phenylsulfonyl)oxirane, (9S)-9-hydroxy-6′-methoxy-1-[(2,3,4-trifluorophenyl)methyl]-cinchonanium bromide, Quinidine DerivativeEpoxidation
Friedel-Crafts, naphthalen-1-ol, tert-butyl (Z)-(1-benzyl-2-oxoindolin-3-ylidene)carbamate, tert-butyl (R)-(1-benzyl-3-(1-hydroxynaphthalen-2-yl)-2-oxoindolin-3-yl)carbamate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeFriedel-Crafts, Friedel-Crafts alkylation
Cyclization, substituted (E)-2-acetylbut-2-enenitrile, cyclohexanone, 2,4-disubstituted (4R,4aS,8aR)-8a-hydroxy-4a,5,6,7,8,8a-hexahydro-4H-chromene-3-carbonitrile, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeCyclization, Cyclization, Further Cyclizations, Michael Addition
[4+2]-Cycloaddition, beta-substituted cyclic enones, polyconjugated malononitriles, substituted (1R,3S,4R)-1-methyl-5-oxo-3-((E)-prop-1-en-1-yl)bicyclo[2.2.2]octane-2,2-dicarbonitrile, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine Derivative[4+2]-Cycloaddition, Cycloaddition, Diels-Alder reaction
Michael Addition, isatylidine malononitriles, methylketones, substituted (R)-2-(2-oxo-3-(2-oxopropyl)indolin-3-yl)malononitrile, 1,1′-Binaphthyl-2,2′-diyl hydrogen phosphate, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeMichael, Michael Addition
Sulfenylation, ethyl 1-benzyl-4-(4-chlorobenzyl)-2-methyl-5-oxo-4,5-dihydro-1H-pyrrole-3-carboxylate, 1-(phenylthio)pyrrolidine-2,5-dione, alpha‐sulfenylated carbonyl compounds, (9S)-(9′′S)-9,9′′-[1,4-phthalazinediylbis(oxy)]bis[6′-methoxy-cinchonan, Quinidine DerivativeSulfenylation
Nitro-Mannich, substituted tert-butyl ((phenylsulfonyl)methyl)carbamate, nitroalkanes, (1R,2S)-1,2-disubstituted tert-butyl (2-nitroethyl)carbamate, (9R)-9-[[[[3,5-bis(trifluoromethyl)phenyl]amino]carbonyl]amino]-6′-methoxy-1-(phenylmethyl)-cinchonanium bromide, Quinidine DerivativeMannich, Nitro-Mannich
Addition, aldehydes, diethylzinc, (R)-1-substituted propan-1-ol, N-[(9R)-6′-methoxycinchonan-9-yl]-P,P- diphenyl-phosphinic amide, Quinidine DerivativeAddition
Spirocyclization, substituted (E)-6-(4-hydroxyphenyl)hex-3-en-2-one, cyclohexadienone containing hindered spirocyclic ethers, 3-[[(9R)-6′-methoxycinchonan-9-yl]amino]-4-[[(1R)-1-phenylethyl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeDearomatization, Further reactions, Michael Addition, Oxa-Michael Addition, Spirocyclization
