Spirocyclization, substituted 3-(hydroxymethylene)benzofuran-2(3H)-one, alpha,beta-unsaturated methylketones, spirocyclic benzofuranones, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeAldol, Aldol, Michael, Michael Addition, Spirocyclization Spirocyclization, 2-arylideneindane-1,3-diones, nitro aldehydes, spiro-1,3-indandiones with three stereocenters, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeAldol, Aldol, Michael, Michael Addition, Spirocyclization Cyclization, substituted 2-(2-oxoethyl)malononitrile, (E)-1-nitroalk-1-enes, 2,4-disubstituted (1S,2R)-1-cyano-3-nitrocyclopent-3-ene-1-carboxamide, 3-[[(9R)-6′-methoxycinchonan-9-yl]amino]-4-[(phenylmethyl)amino]-3-cyclobutene-1,2-dithione, Quinidine DerivativeCascade reaction, Cyclization, Cyclization, Further Cyclizations, Henry, Henry, Michael, Michael Addition Cyclization, substituted 2-nitro-5-oxopentanoate, (E)-1-nitroalk-1-enes, densely functionalised cyclohexanes, 3-[[[3,5-bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinidine DerivativeCascade reaction, Cyclization, Cyclization, Further Cyclizations, Henry, Henry, Michael, Michael Addition Mannich reaction, substitutedtert-butyl (tosylmethyl)carbamate, substituted tert-butyl ethylidenecarbamate, beta-phenyl sulfonyl acetonitrile, substituted tert-butyl (2-cyanoethyl)carbamate, (9S)-9-hydroxy-6′-methoxy-1-[(2-nitrophenyl)methyl]-cinchonanium chloride, Quinidine DerivativeMannich, Mannich Oxa-Michael Addition, substituted (E)-2-oxopent-3-enoate, 7-substituted (E)-7-oxo-hept-5-enal, cis‐and trans‐fused pyrano [2,3‐b] pyrans, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeCycloaddition, Diels-Alder reaction, Michael Addition, Oxa-Michael Addition Oxa-Michael Addition, S-(2,6-dimethylphenyl) (E)-4-hydroxybut-2-enethioate, pivalaldehyde, S-(2,6-dimethylphenyl) 2-((2S,4S)-2-(tert-butyl)-1,3-dioxolan-4-yl)ethanethioate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′- methoxycinchonan-9-yl]thiourea, Quinidine DerivativeCyclization, Cyclization, Further Cyclizations, Michael Addition, Oxa-Michael Addition Michael Addition, substituted 2-azido-2,3-dihydro-1H-inden-1-one, (E)-4-substituted-2-oxobut-3-enoate, α-chiral tertiary azides, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeMichael, Michael Addition Chlorination, 3‐aryloxindoles, N-chlorsuccinimid, 3,5-disubstituted tert-butyl 3-chloro-2-oxoindoline-1-carboxylate, 6′-methoxy-(9S)-cinchonan-9-ol-9-benzoate, Quinidine DerivativeChlorination Spirocyclization, alkyl dihalides, oxindoles, tert-butyl (S)-2-oxo-3′,4′-dihydro-1’H-spiro[indoline-3,2′-naphthalene]-1-carboxylate, (9S)-9-[(2R)-2-[[(1,1-dimethylethoxy)carbonyl]amino]-3-methyl-1-oxobutoxy]-1-(9-phenanthrenylmethyl)-cinchonanium bromide, Quinidine DerivativeSpirocyclization« Older EntriesNext Entries »
Spirocyclization, substituted 3-(hydroxymethylene)benzofuran-2(3H)-one, alpha,beta-unsaturated methylketones, spirocyclic benzofuranones, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeAldol, Aldol, Michael, Michael Addition, Spirocyclization
Spirocyclization, 2-arylideneindane-1,3-diones, nitro aldehydes, spiro-1,3-indandiones with three stereocenters, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeAldol, Aldol, Michael, Michael Addition, Spirocyclization
Cyclization, substituted 2-(2-oxoethyl)malononitrile, (E)-1-nitroalk-1-enes, 2,4-disubstituted (1S,2R)-1-cyano-3-nitrocyclopent-3-ene-1-carboxamide, 3-[[(9R)-6′-methoxycinchonan-9-yl]amino]-4-[(phenylmethyl)amino]-3-cyclobutene-1,2-dithione, Quinidine DerivativeCascade reaction, Cyclization, Cyclization, Further Cyclizations, Henry, Henry, Michael, Michael Addition
Cyclization, substituted 2-nitro-5-oxopentanoate, (E)-1-nitroalk-1-enes, densely functionalised cyclohexanes, 3-[[[3,5-bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinidine DerivativeCascade reaction, Cyclization, Cyclization, Further Cyclizations, Henry, Henry, Michael, Michael Addition
Mannich reaction, substitutedtert-butyl (tosylmethyl)carbamate, substituted tert-butyl ethylidenecarbamate, beta-phenyl sulfonyl acetonitrile, substituted tert-butyl (2-cyanoethyl)carbamate, (9S)-9-hydroxy-6′-methoxy-1-[(2-nitrophenyl)methyl]-cinchonanium chloride, Quinidine DerivativeMannich, Mannich
Oxa-Michael Addition, substituted (E)-2-oxopent-3-enoate, 7-substituted (E)-7-oxo-hept-5-enal, cis‐and trans‐fused pyrano [2,3‐b] pyrans, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeCycloaddition, Diels-Alder reaction, Michael Addition, Oxa-Michael Addition
Oxa-Michael Addition, S-(2,6-dimethylphenyl) (E)-4-hydroxybut-2-enethioate, pivalaldehyde, S-(2,6-dimethylphenyl) 2-((2S,4S)-2-(tert-butyl)-1,3-dioxolan-4-yl)ethanethioate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′- methoxycinchonan-9-yl]thiourea, Quinidine DerivativeCyclization, Cyclization, Further Cyclizations, Michael Addition, Oxa-Michael Addition
Michael Addition, substituted 2-azido-2,3-dihydro-1H-inden-1-one, (E)-4-substituted-2-oxobut-3-enoate, α-chiral tertiary azides, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeMichael, Michael Addition
Chlorination, 3‐aryloxindoles, N-chlorsuccinimid, 3,5-disubstituted tert-butyl 3-chloro-2-oxoindoline-1-carboxylate, 6′-methoxy-(9S)-cinchonan-9-ol-9-benzoate, Quinidine DerivativeChlorination
Spirocyclization, alkyl dihalides, oxindoles, tert-butyl (S)-2-oxo-3′,4′-dihydro-1’H-spiro[indoline-3,2′-naphthalene]-1-carboxylate, (9S)-9-[(2R)-2-[[(1,1-dimethylethoxy)carbonyl]amino]-3-methyl-1-oxobutoxy]-1-(9-phenanthrenylmethyl)-cinchonanium bromide, Quinidine DerivativeSpirocyclization
