Spirocyclization, 3-substituted cyclopent-2-en-1-one, substituted 3-vinylbenzo[d]isothiazole 1,1-dioxide, substituted (3R,3a’S,6a’S)-2′,3′,3a’,6a’-tetrahydro-2H,4’H-spiro[benzo[d]isothiazole-3,1′-pentalen]-4′-one 1,1-dioxide, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeCascade reaction, Spirocyclization Spirocyclization, substituted (E)-2-ethylidene-2,3-dihydro-1H-inden-1-one, 2-mercaptobenzaldehyde, spirothiochromanones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeAldol, Aldol, Michael Addition, Spirocyclization, Sulfa-Michael Domino Michael Addition, 3-phenylpropanal, (E)-2-(2-nitrovinyl)phenol, (3R,4S)-3-benzyl-4-(nitromethyl)chroman-2-one, L-proline, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeCyclization, Cyclization, Further Cyclizations, Lactonization, Michael Addition, Oxa-Michael Addition [4+2] Annulation, 2,3-dioxopyrrolidine derivatives, allene ketones, (R)-6-benzyl-4-(3-bromophenyl)-2-(2-oxo-2-phenylethyl)-5,6-dihydropyrano[2,3-c]pyrrol-7(4H)-one, 6′-methoxy-(9S)-Cinchonan-9-ol-9-benzoate, Quinidine Derivative[4+2]-Cycloaddition, Cyclization Bromocyclization, olefinic dicarbonyl compounds, N-bromosuccinimide, 5-substituted (5-(bromomethyl)-2-phenyl-4,5-dihydrofuran-3-yl)(phenyl)methanone, (9S)-6′-methoxy-9-[N-(2,4,6-trimethoxyphenyl)carbamothioate]-cinchonan-9-ol, Quinidine DerivativeCyclization, Further Cyclizations, Intramolecular cyclization Bromolactonization, styrene-type carboxylic acids, N-bromosuccinimide, (3S)-substituted (R)-4-bromo-isochroman-1-one, (9S)-6′-methoxy-9-[N-(2,4-dimethoxyphenyl)carbamothioate]-cinchonan-9-ol, Quinidine DerivativeCyclization, Lactonization Bromolactonization, olefinic acids, N-bromosuccinimide, (6S)-substituted (R)-5-bromo-tetrahydro-2H-pyran-2-one, (9S)-6′-methoxy-9-[N-(2,4-dimethoxyphenyl)carbamothioate]-cinchonan-9-ol, Quinidine DerivativeCyclization, Lactonization Trifluoromethylthiolation, azlactones, 2-((trifluoromethyl)thio)isoindoline-1,3-dione, (R)-4-isopropyl-2-(4-methoxyphenyl)-4-((trifluoromethyl)thio)oxazol-5(4H)-one, 1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-9-hydroxy-6′-methoxy-cinchonanium bromide, Quinidine DerivativeTrifluoro-methylthiolation Sulfenylation, deconjugated butyrolactams, 1-((4-fluorophenyl)thio)pyrrolidine-2,5-dione, ethyl (S)-1,4-dibenzyl-4-((4-fluorophenyl)thio)-2-methyl-5-oxo-4,5-dihydro-1H-pyrrole-3-carboxylate, (9S)-(9′′S)-9,9′′-[1,4-phthalazinediylbis(oxy)]bis[6′-methoxy-cinchonan, Quinidine DerivativeSulfenylation Cyclization, gamma-aryl-substituted enals, (E)-substituted nitroethene, cyclohexenol derivatives, (2S)-2-[[2-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]-3,3-dimethyl-N-(phenylmethyl)-butanamide, Quinidine DerivativeCyclization, Cyclization, Further Cyclizations« Older EntriesNext Entries »
Spirocyclization, 3-substituted cyclopent-2-en-1-one, substituted 3-vinylbenzo[d]isothiazole 1,1-dioxide, substituted (3R,3a’S,6a’S)-2′,3′,3a’,6a’-tetrahydro-2H,4’H-spiro[benzo[d]isothiazole-3,1′-pentalen]-4′-one 1,1-dioxide, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeCascade reaction, Spirocyclization
Spirocyclization, substituted (E)-2-ethylidene-2,3-dihydro-1H-inden-1-one, 2-mercaptobenzaldehyde, spirothiochromanones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeAldol, Aldol, Michael Addition, Spirocyclization, Sulfa-Michael
Domino Michael Addition, 3-phenylpropanal, (E)-2-(2-nitrovinyl)phenol, (3R,4S)-3-benzyl-4-(nitromethyl)chroman-2-one, L-proline, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeCyclization, Cyclization, Further Cyclizations, Lactonization, Michael Addition, Oxa-Michael Addition
[4+2] Annulation, 2,3-dioxopyrrolidine derivatives, allene ketones, (R)-6-benzyl-4-(3-bromophenyl)-2-(2-oxo-2-phenylethyl)-5,6-dihydropyrano[2,3-c]pyrrol-7(4H)-one, 6′-methoxy-(9S)-Cinchonan-9-ol-9-benzoate, Quinidine Derivative[4+2]-Cycloaddition, Cyclization
Bromocyclization, olefinic dicarbonyl compounds, N-bromosuccinimide, 5-substituted (5-(bromomethyl)-2-phenyl-4,5-dihydrofuran-3-yl)(phenyl)methanone, (9S)-6′-methoxy-9-[N-(2,4,6-trimethoxyphenyl)carbamothioate]-cinchonan-9-ol, Quinidine DerivativeCyclization, Further Cyclizations, Intramolecular cyclization
Bromolactonization, styrene-type carboxylic acids, N-bromosuccinimide, (3S)-substituted (R)-4-bromo-isochroman-1-one, (9S)-6′-methoxy-9-[N-(2,4-dimethoxyphenyl)carbamothioate]-cinchonan-9-ol, Quinidine DerivativeCyclization, Lactonization
Bromolactonization, olefinic acids, N-bromosuccinimide, (6S)-substituted (R)-5-bromo-tetrahydro-2H-pyran-2-one, (9S)-6′-methoxy-9-[N-(2,4-dimethoxyphenyl)carbamothioate]-cinchonan-9-ol, Quinidine DerivativeCyclization, Lactonization
Trifluoromethylthiolation, azlactones, 2-((trifluoromethyl)thio)isoindoline-1,3-dione, (R)-4-isopropyl-2-(4-methoxyphenyl)-4-((trifluoromethyl)thio)oxazol-5(4H)-one, 1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-9-hydroxy-6′-methoxy-cinchonanium bromide, Quinidine DerivativeTrifluoro-methylthiolation
Sulfenylation, deconjugated butyrolactams, 1-((4-fluorophenyl)thio)pyrrolidine-2,5-dione, ethyl (S)-1,4-dibenzyl-4-((4-fluorophenyl)thio)-2-methyl-5-oxo-4,5-dihydro-1H-pyrrole-3-carboxylate, (9S)-(9′′S)-9,9′′-[1,4-phthalazinediylbis(oxy)]bis[6′-methoxy-cinchonan, Quinidine DerivativeSulfenylation
Cyclization, gamma-aryl-substituted enals, (E)-substituted nitroethene, cyclohexenol derivatives, (2S)-2-[[2-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]-3,3-dimethyl-N-(phenylmethyl)-butanamide, Quinidine DerivativeCyclization, Cyclization, Further Cyclizations
