Aldol reaction, 1-Methylisatin, ((2,2-difluoro-1-phenylvinyl)oxy)trimethylsilane, 3-difluoroalkyl 3-hydroxyoxindoles, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]-urea, Quinidine DerivativeAldol, Aldol Michael Addition, tert-butyl (E)-4-(3-(3,5-dichlorophenyl)-4,4,4-trifluorobut-2-enoyl)-2-methylbenzoate, nitromethane, tert-butyl (R)-4-(3-(3,5-dichlorophenyl)-4,4,4-trifluoro-3-(nitromethyl)butanoyl)-2-methylbenzoate, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeMichael, Michael Addition Spirocyclization, 2-pyrones, substituted trifluoroethylisatin ketimines, substituted tricycle-fused dispirooxindoles, Dihydroquinine BaseCascade reaction, Spirocyclization Cyanation, substituted (E)-4,4,4-trifluorobut-2-enoyl, 2-hydroxy-2-methylpropanenitrile, substituted (R)-3-cyano-4,4,4-trifluorobutanoyl, (9S)-1-[[2,5-bis(trifluoromethyl)phenyl]methyl]-6′,9-dimethoxy-cinchonanium bromide, Quinidine DerivativeCyanation, Michael, Michael Addition Amination, 5,7-dimethyl-3-phenylindolin-2-one, di‐tert‐butyl azodicarboxylate, di-tert-butyl (S)-1-(5,7-dimethyl-2-oxo-3-phenylindolin-3-yl)hydrazine-1,2-dicarboxylate, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(9S)-6′-methoxycinchonan-9-yl]-thiourea, Quinidine Derivativealpha-Amination, Amination Desymmetrization, 4-hydroxy-4-methyldihydro-2H-pyran-2,6(3H)-dione, (R)-2-(2-methyl-4-oxooxetan-2-yl)acetic acid, Dihydroquinine BaseDesymmetrization Amination, fluorinated keto esters, di‐tert‐butyl azodicarboxylate, diethyl (R)-1-(2-fluoro-1-methoxy-1,3-dioxo-3-phenylpropan-2-yl)hydrazine-1,2-dicarboxylate, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]-guanidine, Quinidine Derivativealpha-Amination, Amination Amination, 1,3-dibenzylindolin-2-one, di‐tert‐butyl azodicarboxylate, diethyl (S)-1-(1,3-dibenzyl-2-oxoindolin-3-yl)hydrazine-1,2-dicarboxylate, (9S)-(9′′S)-9,9′′-[[5-[4-[1-(phenylmethyl)-1H-1,2,3-triazol-4-yl]butyl]- 3,6-pyridazinediyl]bis(oxy)]bis[6′-methoxy-cinchonan, Quinidine Derivativealpha-Amination, Amination Iodoetherification, substituted β,γ-unsaturated oximes, N-iodosuccinimide, substituted 2-isoxazolines, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydrocinchonan-9-yl]thiourea, Dihydrocinchonidine DerivativeCyclization, Iodination, Iodoetherification, Isoxazoline cyclization Friedel Crafts Alkylation, methyleneoxindoles, hydroxyindoles, substituted tert-butyl (2-((3R,4S)-2-oxo-2,3,4,7-tetrahydropyrano[2,3-e]indol-3-yl)phenyl)carbamate, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeFriedel-Crafts, Friedel-Crafts alkylation/lactonization, Lactonization« Older EntriesNext Entries »
Aldol reaction, 1-Methylisatin, ((2,2-difluoro-1-phenylvinyl)oxy)trimethylsilane, 3-difluoroalkyl 3-hydroxyoxindoles, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]-urea, Quinidine DerivativeAldol, Aldol
Michael Addition, tert-butyl (E)-4-(3-(3,5-dichlorophenyl)-4,4,4-trifluorobut-2-enoyl)-2-methylbenzoate, nitromethane, tert-butyl (R)-4-(3-(3,5-dichlorophenyl)-4,4,4-trifluoro-3-(nitromethyl)butanoyl)-2-methylbenzoate, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeMichael, Michael Addition
Spirocyclization, 2-pyrones, substituted trifluoroethylisatin ketimines, substituted tricycle-fused dispirooxindoles, Dihydroquinine BaseCascade reaction, Spirocyclization
Cyanation, substituted (E)-4,4,4-trifluorobut-2-enoyl, 2-hydroxy-2-methylpropanenitrile, substituted (R)-3-cyano-4,4,4-trifluorobutanoyl, (9S)-1-[[2,5-bis(trifluoromethyl)phenyl]methyl]-6′,9-dimethoxy-cinchonanium bromide, Quinidine DerivativeCyanation, Michael, Michael Addition
Amination, 5,7-dimethyl-3-phenylindolin-2-one, di‐tert‐butyl azodicarboxylate, di-tert-butyl (S)-1-(5,7-dimethyl-2-oxo-3-phenylindolin-3-yl)hydrazine-1,2-dicarboxylate, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(9S)-6′-methoxycinchonan-9-yl]-thiourea, Quinidine Derivativealpha-Amination, Amination
Desymmetrization, 4-hydroxy-4-methyldihydro-2H-pyran-2,6(3H)-dione, (R)-2-(2-methyl-4-oxooxetan-2-yl)acetic acid, Dihydroquinine BaseDesymmetrization
Amination, fluorinated keto esters, di‐tert‐butyl azodicarboxylate, diethyl (R)-1-(2-fluoro-1-methoxy-1,3-dioxo-3-phenylpropan-2-yl)hydrazine-1,2-dicarboxylate, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]-guanidine, Quinidine Derivativealpha-Amination, Amination
Amination, 1,3-dibenzylindolin-2-one, di‐tert‐butyl azodicarboxylate, diethyl (S)-1-(1,3-dibenzyl-2-oxoindolin-3-yl)hydrazine-1,2-dicarboxylate, (9S)-(9′′S)-9,9′′-[[5-[4-[1-(phenylmethyl)-1H-1,2,3-triazol-4-yl]butyl]- 3,6-pyridazinediyl]bis(oxy)]bis[6′-methoxy-cinchonan, Quinidine Derivativealpha-Amination, Amination
Iodoetherification, substituted β,γ-unsaturated oximes, N-iodosuccinimide, substituted 2-isoxazolines, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydrocinchonan-9-yl]thiourea, Dihydrocinchonidine DerivativeCyclization, Iodination, Iodoetherification, Isoxazoline cyclization
Friedel Crafts Alkylation, methyleneoxindoles, hydroxyindoles, substituted tert-butyl (2-((3R,4S)-2-oxo-2,3,4,7-tetrahydropyrano[2,3-e]indol-3-yl)phenyl)carbamate, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeFriedel-Crafts, Friedel-Crafts alkylation/lactonization, Lactonization
