Mukaiyama-Mannich reaction, ethyl benzo[d]isothiazole-3-carboxylate 1,1-dioxide, ((2,2-difluoro-1-phenylvinyl)oxy)trimethylsilane, ethyl (S)-3-(1,1-difluoro-2-oxo-2-phenylethyl)-2,3-dihydrobenzo[d]isothiazole-3-carboxylate 1,1-dioxide, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-Urea, Dihydroquinine DerivativeMannich, Mukaiyama-Mannich γ-Alkylation, α‐branched enals, 4,4′-Bis(dimethylamino)benzhydrol, (R,E)-4-benzyl-5,5-bis(4-(dimethylamino)phenyl)-2-methylpent-2-enal, (S)-2,2′-Dihydroxy-3,3′-bis(4-nitrophenyl)-1,1′-binaphthalene cyclic phosphate, (9R)-9-Aminocinchonan-6′-ol, Cupreidine DerivativeAlkylation, Alkylation Fluorination, 3-Substituted (E)-2-(2-hydroxybenzoyl)acrylate, N-fluorbenzolsulfonimid, fluorinated flavanone derivatives, (9S)-9-[[4-(trifluoromethyl)phenyl]methoxy]-cinchonan-6′-ol, Cupreidine DerivativeFluorination, Fluorination of beta-ketoester, Michael Addition, Oxa-Michael Addition Aminohydroxylation, methyl cinnamate, ((ethoxycarbonyl)imino)trioxoosmium, methyl (2R,3S)-3-((ethoxycarbonyl)amino)-2-hydroxy-3-phenylpropanoate, (8α,9R)-(8′′α,9′′R)-9,9′′-[1,4-Phthalazinediylbis(oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine DerivativeAminohydroxylation, Further reactions Spirocyclization, 3-Amino Oxindoles, alpha,beta unsaturated ketones, Spiro[oxindol-3,2′-pyrrol], (9S)-9-(1-naphthalenylmethoxy)-cinchonan-6′-ol, Cupreidine DerivativeMichael, Michael Addition, Spirocyclization Diels Alder, beta,gamma-unsaturated-alpha-ketoesters, 2,4-disubstituted oxazol-5(4H)-one, substituted 3-acetamido-2-oxo-3,4-dihydro-2H-pyran-6-carboxylate, (9S)-9-(1-naphthalenylmethoxy)-cinchonan-6′-ol, Cupreidine Derivative[4+2]-Cycloaddition, Cycloaddition, Diels-Alder reaction Michael Addition, tert-butyl 2-oxocyclopentane-1-carboxylate, acrylaldehyde, tert-butyl (S)-2-oxo-1-(3-oxopropyl)cyclopentane-1-carboxylate, (9S)-9-(9-Phenanthrenyloxy)cinchonan-6′-ol, Cupreidine DerivativeMichael, Michael Addition Michael Addition, diketopiperazines, alpha,beta-unsaturated ketones, substituted methyl (S)-1,4-dibenzyl-3,5,6-trioxo-2-(3-oxopropyl)piperazine-2-carboxylate, (9S)-9-(phenylmethoxy)-cinchonan-6′-ol, Cupreidine DerivativeMichael, Michael Addition Allylic Amination, allyl (E)-2-cyanohex-2-enoate, di-tert-butyl (E)-diazene-1,2-dicarboxylate, di-tert-butyl (S,E)-1-(6-(allyloxy)-5-cyano-6-oxohex-4-en-3-yl)hydrazine-1,2-dicarboxylate, (8α,9R)-(8′′α,9′′R)-9,9′′-[(2,5-Diphenyl-4,6-pyrimidinediyl)bis(oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine DerivativeAllylic Amination, Amination gamma-Amination, cyclohex-1-ene-1-carbaldehyde, di-tert-butyl (E)-diazene-1,2-dicarboxylate, di-tert-butyl 1-(3-formylcyclohex-2-en-1-yl)hydrazine-1,2-dicarboxylate, (8α,9S)-10,11-Dihydro-6′-methoxycinchonan-9-amine, Dihydroquinine DerivativeAmination, gamma-Amination« Older EntriesNext Entries »
Mukaiyama-Mannich reaction, ethyl benzo[d]isothiazole-3-carboxylate 1,1-dioxide, ((2,2-difluoro-1-phenylvinyl)oxy)trimethylsilane, ethyl (S)-3-(1,1-difluoro-2-oxo-2-phenylethyl)-2,3-dihydrobenzo[d]isothiazole-3-carboxylate 1,1-dioxide, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-Urea, Dihydroquinine DerivativeMannich, Mukaiyama-Mannich
γ-Alkylation, α‐branched enals, 4,4′-Bis(dimethylamino)benzhydrol, (R,E)-4-benzyl-5,5-bis(4-(dimethylamino)phenyl)-2-methylpent-2-enal, (S)-2,2′-Dihydroxy-3,3′-bis(4-nitrophenyl)-1,1′-binaphthalene cyclic phosphate, (9R)-9-Aminocinchonan-6′-ol, Cupreidine DerivativeAlkylation, Alkylation
Fluorination, 3-Substituted (E)-2-(2-hydroxybenzoyl)acrylate, N-fluorbenzolsulfonimid, fluorinated flavanone derivatives, (9S)-9-[[4-(trifluoromethyl)phenyl]methoxy]-cinchonan-6′-ol, Cupreidine DerivativeFluorination, Fluorination of beta-ketoester, Michael Addition, Oxa-Michael Addition
Aminohydroxylation, methyl cinnamate, ((ethoxycarbonyl)imino)trioxoosmium, methyl (2R,3S)-3-((ethoxycarbonyl)amino)-2-hydroxy-3-phenylpropanoate, (8α,9R)-(8′′α,9′′R)-9,9′′-[1,4-Phthalazinediylbis(oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine DerivativeAminohydroxylation, Further reactions
Spirocyclization, 3-Amino Oxindoles, alpha,beta unsaturated ketones, Spiro[oxindol-3,2′-pyrrol], (9S)-9-(1-naphthalenylmethoxy)-cinchonan-6′-ol, Cupreidine DerivativeMichael, Michael Addition, Spirocyclization
Diels Alder, beta,gamma-unsaturated-alpha-ketoesters, 2,4-disubstituted oxazol-5(4H)-one, substituted 3-acetamido-2-oxo-3,4-dihydro-2H-pyran-6-carboxylate, (9S)-9-(1-naphthalenylmethoxy)-cinchonan-6′-ol, Cupreidine Derivative[4+2]-Cycloaddition, Cycloaddition, Diels-Alder reaction
Michael Addition, tert-butyl 2-oxocyclopentane-1-carboxylate, acrylaldehyde, tert-butyl (S)-2-oxo-1-(3-oxopropyl)cyclopentane-1-carboxylate, (9S)-9-(9-Phenanthrenyloxy)cinchonan-6′-ol, Cupreidine DerivativeMichael, Michael Addition
Michael Addition, diketopiperazines, alpha,beta-unsaturated ketones, substituted methyl (S)-1,4-dibenzyl-3,5,6-trioxo-2-(3-oxopropyl)piperazine-2-carboxylate, (9S)-9-(phenylmethoxy)-cinchonan-6′-ol, Cupreidine DerivativeMichael, Michael Addition
Allylic Amination, allyl (E)-2-cyanohex-2-enoate, di-tert-butyl (E)-diazene-1,2-dicarboxylate, di-tert-butyl (S,E)-1-(6-(allyloxy)-5-cyano-6-oxohex-4-en-3-yl)hydrazine-1,2-dicarboxylate, (8α,9R)-(8′′α,9′′R)-9,9′′-[(2,5-Diphenyl-4,6-pyrimidinediyl)bis(oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine DerivativeAllylic Amination, Amination
gamma-Amination, cyclohex-1-ene-1-carbaldehyde, di-tert-butyl (E)-diazene-1,2-dicarboxylate, di-tert-butyl 1-(3-formylcyclohex-2-en-1-yl)hydrazine-1,2-dicarboxylate, (8α,9S)-10,11-Dihydro-6′-methoxycinchonan-9-amine, Dihydroquinine DerivativeAmination, gamma-Amination
