Mannich reaction, 3-(2-isothiocyanatoacetyl)oxazolidin-2-one, protected imines, 5-substituted ethyl 2-thioxo-1-tosylimidazolidine-4-carboxylate, (8α,9R)-Cinchonan-6′,9-diol-9-benzoate, Cupreine DerivativeMannich, Mannich Cascade reaction, substituted 2-(iminomethyl)phenol, diethyl acryloylphosphonates, substituted 2,3,3a,9b-tetrahydrochromeno[4,3-b]pyrrol-4(1H)-one, Dihydroquinine BaseCascade reaction Spirocyclization, substituted 3-hydroxy-2-oxopropanoate, substituted 4-ethylidene-2,5-diphenyl-2,4-dihydro-3H-pyrazol-3-one, spirocyclohexenes, Dihydroquinine Base[3+3]-Annulation, Cyclization, Further Cyclizations, Spirocyclization Atropisomer Synthesis, substituted 2-methyl-N-phenylpropane-2-sulfinamide, 2-(((tert-butoxycarbonyl)oxy)methyl)acrylates, atropisomeric sulfinamides, Dihydroquinine BaseAlkylation, Allylic Alkylation, Atropisomer synthesis Cascade reaction, α-hydroxy ketones, α-amino ketones, 2-isocyanoacetates, lactone oxazolines, lactam oxazolines, silver oxide, N-[(8α,9S)-10,11-dihydro-6′-methoxycinchonan -9-yl]-2-(diphenylphosphino)-benzamide, Dihydroquinine DerivativeCascade reaction, Cyclization, Cyclization, Further Cyclizations Cyclization, benzaldehyde, vinylogous isocyano esters, isoxazolines, silver oxide, 3-[[2,6-bis(1-methylethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Dihydroquinine DerivativeAldol, Cyclization, Cyclization, Further Cyclizations, Vinylogous Aldol Desymmetrization, cyclohexane-1,2-diol, benzoyl chloride, (1S,2R)-2-hydroxycyclohexyl benzoate, N,N-Dimethyl-aminodihydroquincorine, Dihydroquinine DerivativeDesymmetrization Annulation, unsaturated pyrazolones, ynones, (S,Z)-3-methyl-1,4,8-triphenyl-4,5-dihydrooxocino[2,3-c]pyrazol-6(1H)-one, (8α,9S)-10,11-Dihydro-6′-methoxycinchonan-9-amine, Dihydroquinine Derivative[4+4] Annulation, Cyclization, Further Cyclizations Addition, substituted 2-((phenylsulfonyl)methyl)phenol, α-cyanoketones, substituted chroman-2-one, substituted (3S)-2-hydroxychromane-3-carbonitrile, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeAddition Diels-Alder Reaction, 3‐vinylindoles, 1-phenyl-1H-pyrrole-2,5-dione, trifluoroacetic anhydride, (3aS,10aS,10bS)-2-phenyl-10-(2,2,2-trifluoroacetyl)-4,10,10a,10b-tetrahydropyrrolo[3,4-a]carbazole-1,3(2H,3aH)-dione, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeCycloaddition, Diels-Alder reaction« Older EntriesNext Entries »
Mannich reaction, 3-(2-isothiocyanatoacetyl)oxazolidin-2-one, protected imines, 5-substituted ethyl 2-thioxo-1-tosylimidazolidine-4-carboxylate, (8α,9R)-Cinchonan-6′,9-diol-9-benzoate, Cupreine DerivativeMannich, Mannich
Cascade reaction, substituted 2-(iminomethyl)phenol, diethyl acryloylphosphonates, substituted 2,3,3a,9b-tetrahydrochromeno[4,3-b]pyrrol-4(1H)-one, Dihydroquinine BaseCascade reaction
Spirocyclization, substituted 3-hydroxy-2-oxopropanoate, substituted 4-ethylidene-2,5-diphenyl-2,4-dihydro-3H-pyrazol-3-one, spirocyclohexenes, Dihydroquinine Base[3+3]-Annulation, Cyclization, Further Cyclizations, Spirocyclization
Atropisomer Synthesis, substituted 2-methyl-N-phenylpropane-2-sulfinamide, 2-(((tert-butoxycarbonyl)oxy)methyl)acrylates, atropisomeric sulfinamides, Dihydroquinine BaseAlkylation, Allylic Alkylation, Atropisomer synthesis
Cascade reaction, α-hydroxy ketones, α-amino ketones, 2-isocyanoacetates, lactone oxazolines, lactam oxazolines, silver oxide, N-[(8α,9S)-10,11-dihydro-6′-methoxycinchonan -9-yl]-2-(diphenylphosphino)-benzamide, Dihydroquinine DerivativeCascade reaction, Cyclization, Cyclization, Further Cyclizations
Cyclization, benzaldehyde, vinylogous isocyano esters, isoxazolines, silver oxide, 3-[[2,6-bis(1-methylethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Dihydroquinine DerivativeAldol, Cyclization, Cyclization, Further Cyclizations, Vinylogous Aldol
Desymmetrization, cyclohexane-1,2-diol, benzoyl chloride, (1S,2R)-2-hydroxycyclohexyl benzoate, N,N-Dimethyl-aminodihydroquincorine, Dihydroquinine DerivativeDesymmetrization
Annulation, unsaturated pyrazolones, ynones, (S,Z)-3-methyl-1,4,8-triphenyl-4,5-dihydrooxocino[2,3-c]pyrazol-6(1H)-one, (8α,9S)-10,11-Dihydro-6′-methoxycinchonan-9-amine, Dihydroquinine Derivative[4+4] Annulation, Cyclization, Further Cyclizations
Addition, substituted 2-((phenylsulfonyl)methyl)phenol, α-cyanoketones, substituted chroman-2-one, substituted (3S)-2-hydroxychromane-3-carbonitrile, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeAddition
Diels-Alder Reaction, 3‐vinylindoles, 1-phenyl-1H-pyrrole-2,5-dione, trifluoroacetic anhydride, (3aS,10aS,10bS)-2-phenyl-10-(2,2,2-trifluoroacetyl)-4,10,10a,10b-tetrahydropyrrolo[3,4-a]carbazole-1,3(2H,3aH)-dione, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeCycloaddition, Diels-Alder reaction
