Total synthesis of (+)-hygrine via asymmetric phase-transfer catalytic alkylation.

DOI Number:

10.1021/jo061108l
Link to literature

Reaction Category:

Alkylation | alpha-Alkylation

MOP ID:

MOP_0000369

Educt:

tert-butyl 2-((diphenylmethylene)amino)acetate, 3-bromo-2-methylprop-1-ene

Product:

tert-butyl (S)-2-((diphenylmethylene)amino)-4-methylpent-4-enoate

Catalyst:

(8α,9R)-(8′′α,9′′R)-1,1′′-[2,7-naphthalenediylbis(methylene)]bis[10,11-dihydro-9-(2-propen-1-yloxy)-cinchonanium bromide

Cas No:

480427-57-4

Associated Product from Buchler GmbH:

Dihydrocinchonidine Base

Cas No:

485-64-3