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Michael Addition, tert-butyl (E)-4-(3-(3,5-dichlorophenyl)-4,4,4-trifluorobut-2-enoyl)-2-methylbenzoate, nitromethane, tert-butyl (R)-4-(3-(3,5-dichlorophenyl)-4,4,4-trifluoro-3-(nitromethyl)butanoyl)-2-methylbenzoate, N-[3,5-bis(trifluoromethyl)phenyl]-N′- [(8α,9S)-10,11-dihydro-6′-methoxy- cinchonan-9-yl]-Thiourea, Dihydroquinine Derivative

Michael, Michael Addition

Michael Addition, 1,3-diphenylpropane-1,3-dione, (E)-(2-nitrovinyl)benzene, (S)-2-(2-nitro-1-phenylethyl)-1,3-diphenylpropane-1,3-dione, Dihydroquinine Derivative

Michael, Michael Addition

Allylic Alkylation, anilides, Morita-Baylis-Hillman carbonates, axially chiral anilides, (8α,9R)-(8′′α,9′′R)-9,9′′-[(2,5-Diphenyl-4,6-pyrimidinediyl)bis(oxy)] bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine Derivative

Alkylation, Allylic Alkylation

Friedel-Crafts reaction, ethyl (E)-4-oxopent-2-enoate, 1H-indole, ethyl (R)-2-(1H-indol-3-yl)-4-oxopentanoate, (8α,9S)-10,11-dihydro-6′-methoxy-Cinchonan-9-amine (αS)-α-[[(1,1-dimethylethoxy)carbonyl]amino]benzeneacetate (1:2), Dihydroquinine Derivative

Friedel-Crafts, Friedel-Crafts reaction

Isomerization, trifluoromethyl imines, trifluoromethyl imines, (9S)-9-[(6-chloro-2,5-diphenyl-4-pyrimidinyl)oxy]-1-[[2′-(1,1-dimethylethoxy)[1,1′:3′,1′′-terphenyl]-5′-yl]methyl]-6′-hydroxy-cinchonanium inner salt, Cupreidine Derivative

Isomerization

Desymmetrization, diolefinic diols, N-bromophthalimide, substituted ((3R,5S)-3-allyl-5-(bromomethyl)-tetrahydrofuran-3-yl)methanol, (9S)-9-[N-(4-ethoxyphenyl)carbamothioate]-6′-butoxy-cinchonan-9-ol, Cupreidine Derivative

Cyclization, Cyclization, Desymmetrization, Further Cyclizations

Michael Addition, 1,3-substituted (E)-4,4,4-trifluorobut-2-en-1-one, nitromethane, 1,3-substituted (S)-4,4,4-trifluoro-3-(nitromethyl)-butan-1-one, (9S)-1-[[3,5-bis(1,1-dimethylethyl)phenyl]methyl]-9-butoxy-6′-hydroxy-cinchonanium bromide, Cupreidine Derivative

Michael, Michael Addition

Amination, α-substituted α-cyanoacetates, disubstituted (E)-diazene-1,2-dicarboxylate, substituted 1-(1-cyano-2-ethoxy-2-oxoethyl)hydrazine-1,2-dicarboxylate, (8α,9R)-9-(Phenylmethoxy)-cinchonan-6′-ol, Cupreine Derivative

alpha-Amination, Amination

Amination, α-substituted α-cyanoacetates, disubstituted (E)-diazene-1,2-dicarboxylate, substituted 1-(1-cyano-2-ethoxy-2-oxoethyl)hydrazine-1,2-dicarboxylate, (9S)-9-(phenylmethoxy)-cinchonan-6′-ol, Cupreidine Derivative

alpha-Amination, Amination

Cycloaddition, cyclic enones, azomethine imines, 9-substituted (4aR,8aR)-octahydro-3H,8H-pyrazolo[1,2-a]indazole-3,8-dione, (9R)-9-Aminocinchonan-6′-ol, Cupreidine Derivative

1,3-Dipolar Cycloaddition, Cycloaddition

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