Kinetic resolution of unsaturated amides in a chlorocyclization reaction: concomitant enantiomer differentiation and face selective alkene chlorination by a single catalyst.

DOI Number:

10.1021/ja407241d

Reaction Category:

Educt:

unsaturated amides, N-chlorophthalimide

Product:

(4R,5S,6R)-5-chloro-4-methyl-2,6-diphenyl-5,6-dihydro-4H-1,3-oxazine

Catalyst:

1,4-Bis(9-O-dihydroquinidinyl)phthalazine ((DHQD)2PHAL)

Cas No:

140853-10-7

Associated Product from Buchler GmbH:

1,4-Bis(9-O-dihydroquinidinyl)phthalazine ((DHQD)2PHAL)

Cas No:

140853-10-7