Kinetic resolution of unsaturated amides in a chlorocyclization reaction: concomitant enantiomer differentiation and face selective alkene chlorination by a single catalyst.
DOI Number:
10.1021/ja407241d
Reaction Category:
MOP ID:
MOP_0000551
Educt:
unsaturated amides, N-chlorophthalimide
Product:
(4R,5S,6R)-5-chloro-4-methyl-2,6-diphenyl-5,6-dihydro-4H-1,3-oxazine
Catalyst:
1,4-Bis(9-O-dihydroquinidinyl)phthalazine ((DHQD)2PHAL)
Cas No:
140853-10-7
Associated Product from Buchler GmbH:
1,4-Bis(9-O-dihydroquinidinyl)phthalazine ((DHQD)2PHAL)
Cas No:
140853-10-7