Addition reaction, methyl 2-fluoro-3-((2-fluorophenyl)thio)-3-oxopropanoate, tert-butyl (E)-benzylidenecarbamate, methyl (2R,3S)-3-((tert-butoxycarbonyl)amino)-2-fluoro-2-(((2-fluorophenyl)thio)carbonyl)-3-phenylpropanoate, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-10,11-dihydro-6′-methoxycinchonan- 9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeAddition, Mannich, Mannich Darzens reaction, 2-chloro-1-(4-chlorophenyl)ethan-1-one, 2-naphthaldehyde, (4-chlorophenyl)((2S,3R)-3-(naphthalen-2-yl)oxiran-2-yl)methanone, (1S,2R,4S,5R)-2-((S)-(6-hydroxyquinolin-4-yl)(phenanthren-9-yloxy)methyl)-1-(3,4,5-trifluorobenzyl)-5-vinylquinuclidin-1-ium bromide, Cupreidine DerivativeEpoxidation Aminohydroxylation, methyl cinnamate, benzyl carbamate, methyl (2R,3S)-2-(((benzyloxy)carbonyl)amino)-3-hydroxy-3-phenylpropanoate, 1,4-bis[[(8α,9R)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]oxy]-9,10-Anthracenedione, Dihydroquinine DerivativeAminohydroxylation, Further reactions Mukaiyama-Mannich reaction, ethyl benzo[d]isothiazole-3-carboxylate 1,1-dioxide, ((2,2-difluoro-1-phenylvinyl)oxy)trimethylsilane, ethyl (S)-3-(1,1-difluoro-2-oxo-2-phenylethyl)-2,3-dihydrobenzo[d]isothiazole-3-carboxylate 1,1-dioxide, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-Urea, Dihydroquinine DerivativeFurther reactions, Mukaiyama-Mannich γ-Alkylation, α‐branched enals, 4,4′-Bis(dimethylamino)benzhydrol, (R,E)-4-benzyl-5,5-bis(4-(dimethylamino)phenyl)-2-methylpent-2-enal, (S)-2,2′-Dihydroxy-3,3′-bis(4-nitrophenyl)-1,1′-binaphthalene cyclic phosphate, (9R)-9-Aminocinchonan-6′-ol, Cupreidine DerivativeAlkylation, Alkylation Fluorination, 3-Substituted (E)-2-(2-hydroxybenzoyl)acrylate, N-fluorbenzolsulfonimid, fluorinated flavanone derivatives, (9S)-9-[[4-(trifluoromethyl)phenyl]methoxy]-cinchonan-6′-ol, Cupreidine DerivativeFluorination, Fluorination of beta-ketoester, Michael Addition, Oxa-Michael Addition Aminohydroxylation, methyl cinnamate, ((ethoxycarbonyl)imino)trioxoosmium, methyl (2R,3S)-3-((ethoxycarbonyl)amino)-2-hydroxy-3-phenylpropanoate, (8α,9R)-(8′′α,9′′R)-9,9′′-[1,4-Phthalazinediylbis(oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine DerivativeAminohydroxylation, Further reactions Spirocyclization, 3-Amino Oxindoles, alpha,beta unsaturated ketones, Spiro[oxindol-3,2′-pyrrol], (9S)-9-(1-naphthalenylmethoxy)-cinchonan-6′-ol, Cupreidine DerivativeMichael, Michael Addition, Spirocyclization Diels Alder, beta,gamma-unsaturated-alpha-ketoesters, 2,4-disubstituted oxazol-5(4H)-one, substituted 3-acetamido-2-oxo-3,4-dihydro-2H-pyran-6-carboxylate, (9S)-9-(1-naphthalenylmethoxy)-cinchonan-6′-ol, Cupreidine Derivative[4+2]-Cycloaddition, Cycloaddition, Diels-Alder reaction Michael Addition, tert-butyl 2-oxocyclopentane-1-carboxylate, acrylaldehyde, tert-butyl (S)-2-oxo-1-(3-oxopropyl)cyclopentane-1-carboxylate, (9S)-9-(9-Phenanthrenyloxy)cinchonan-6′-ol, Cupreidine DerivativeMichael, Michael Addition« Older EntriesNext Entries »
Addition reaction, methyl 2-fluoro-3-((2-fluorophenyl)thio)-3-oxopropanoate, tert-butyl (E)-benzylidenecarbamate, methyl (2R,3S)-3-((tert-butoxycarbonyl)amino)-2-fluoro-2-(((2-fluorophenyl)thio)carbonyl)-3-phenylpropanoate, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-10,11-dihydro-6′-methoxycinchonan- 9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeAddition, Mannich, Mannich
Darzens reaction, 2-chloro-1-(4-chlorophenyl)ethan-1-one, 2-naphthaldehyde, (4-chlorophenyl)((2S,3R)-3-(naphthalen-2-yl)oxiran-2-yl)methanone, (1S,2R,4S,5R)-2-((S)-(6-hydroxyquinolin-4-yl)(phenanthren-9-yloxy)methyl)-1-(3,4,5-trifluorobenzyl)-5-vinylquinuclidin-1-ium bromide, Cupreidine DerivativeEpoxidation
Aminohydroxylation, methyl cinnamate, benzyl carbamate, methyl (2R,3S)-2-(((benzyloxy)carbonyl)amino)-3-hydroxy-3-phenylpropanoate, 1,4-bis[[(8α,9R)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]oxy]-9,10-Anthracenedione, Dihydroquinine DerivativeAminohydroxylation, Further reactions
Mukaiyama-Mannich reaction, ethyl benzo[d]isothiazole-3-carboxylate 1,1-dioxide, ((2,2-difluoro-1-phenylvinyl)oxy)trimethylsilane, ethyl (S)-3-(1,1-difluoro-2-oxo-2-phenylethyl)-2,3-dihydrobenzo[d]isothiazole-3-carboxylate 1,1-dioxide, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-Urea, Dihydroquinine DerivativeFurther reactions, Mukaiyama-Mannich
γ-Alkylation, α‐branched enals, 4,4′-Bis(dimethylamino)benzhydrol, (R,E)-4-benzyl-5,5-bis(4-(dimethylamino)phenyl)-2-methylpent-2-enal, (S)-2,2′-Dihydroxy-3,3′-bis(4-nitrophenyl)-1,1′-binaphthalene cyclic phosphate, (9R)-9-Aminocinchonan-6′-ol, Cupreidine DerivativeAlkylation, Alkylation
Fluorination, 3-Substituted (E)-2-(2-hydroxybenzoyl)acrylate, N-fluorbenzolsulfonimid, fluorinated flavanone derivatives, (9S)-9-[[4-(trifluoromethyl)phenyl]methoxy]-cinchonan-6′-ol, Cupreidine DerivativeFluorination, Fluorination of beta-ketoester, Michael Addition, Oxa-Michael Addition
Aminohydroxylation, methyl cinnamate, ((ethoxycarbonyl)imino)trioxoosmium, methyl (2R,3S)-3-((ethoxycarbonyl)amino)-2-hydroxy-3-phenylpropanoate, (8α,9R)-(8′′α,9′′R)-9,9′′-[1,4-Phthalazinediylbis(oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine DerivativeAminohydroxylation, Further reactions
Spirocyclization, 3-Amino Oxindoles, alpha,beta unsaturated ketones, Spiro[oxindol-3,2′-pyrrol], (9S)-9-(1-naphthalenylmethoxy)-cinchonan-6′-ol, Cupreidine DerivativeMichael, Michael Addition, Spirocyclization
Diels Alder, beta,gamma-unsaturated-alpha-ketoesters, 2,4-disubstituted oxazol-5(4H)-one, substituted 3-acetamido-2-oxo-3,4-dihydro-2H-pyran-6-carboxylate, (9S)-9-(1-naphthalenylmethoxy)-cinchonan-6′-ol, Cupreidine Derivative[4+2]-Cycloaddition, Cycloaddition, Diels-Alder reaction
Michael Addition, tert-butyl 2-oxocyclopentane-1-carboxylate, acrylaldehyde, tert-butyl (S)-2-oxo-1-(3-oxopropyl)cyclopentane-1-carboxylate, (9S)-9-(9-Phenanthrenyloxy)cinchonan-6′-ol, Cupreidine DerivativeMichael, Michael Addition
