Highly Enantioselective Synthesis of (R)-α-Alkylserines via Phase-Transfer Catalytic Alkylation of o-Biphenyl-2-oxazoline-4-carboxylic Acid tert-Butyl Ester Using Cinchona-Derived Catalysts.
DOI Number:
10.1021/ol050228x
Reaction Category:
MOP ID:
MOP_0000369
Educt:
o-biphenyl-2-oxazoline-4-carboxylic acid tert-butyl ester, 3-bromoprop-1-ene, (bromomethyl)benzene
Product:
substituited o-biphenyl-2-oxazoline-4-carboxylic acid tert-butyl ester
Catalyst:
1-(9-anthracenylmethyl)-9-(2-propenyloxy)-(8α,9R)-cinchonanium bromide
Cas No:
200132-54-3
Associated Product from Buchler GmbH:
Dihydrocinchonidine Base
Cas No:
485-64-3