Enantioselective Construction of Consecutive Tetrasubstituted Stereogenic Centers by Reaction of α-Substituted β-Nitroacrylates with Oxazol-5-(4H)-ones Catalyzed by Cinchona Alkaloid Sulfonamide Catalysts.
DOI Number:
10.1021/acs.orglett.3c00783
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
α-substituted β-nitroacrylates, oxazol-5-(4H)-ones, methanol
Product:
1-benzyl 4-methyl (2S,3R)-3-(((4-methoxyphenoxy)carbonyl)amino)-2-(nitromethyl)-2,3-diphenylsuccinate
Catalyst:
N-(8α,9S)-Cinchonan-9-yl-8-quinolinesulfonamide
Cas No:
1440939-88-7
Associated Product from Buchler GmbH:
Cinchonidine Base
Cas No:
485-71-2