Synthesis of an advanced precursor of Rivastigmine: Cinchona-derived quaternary ammonium salts as organocatalysts for stereoselective imine reductions.

DOI Number:

10.1016/j.tetlet.2015.08.086

Reaction Category:

Educt:

(S,E)-1-(3-(benzyloxy)phenyl)-N-(1-phenylethyl)ethan-1-imine, trichlorosilane

Product:

(S)-1-(3-(benzyloxy)phenyl)-N-((S)-1-phenylethyl)ethan-1-amine

Catalyst:

(8α,9S)-1-(phenylmethyl)-9-[(2-pyridinylcarbonyl)amino]-Cinchonanium bromide

Cas No:

1809788-51-9

Cas No:

485-71-2