Desymmetrization of gem-diols via water-assisted organocatalytic enantio-and diastereoselective cycloetherification.

DOI Number:

10.1039/D0CC05509C
Link to literature

Reaction Category:

Cyclization | Desymmetrization | Further Cyclizations | Intramolecular cyclization

MOP ID:

MOP_0000561

Educt:

geminal diols

Product:

substituted tetrahydropyran-2-ol

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7

Associated Product from Buchler GmbH:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7