Organocatalytic asymmetric synthesis of highly substituted pyrrolidines bearing a stereogenic quaternary centre at the 3-position.

DOI Number:

10.1039/C8OB02648C
Link to literature

Reaction Category:

Cascade reaction

Educt:

N-Tosyl aminomethyl enones, trans-α-cyano-α,β-unsaturated ketones

Product:

highly substituted pyrrolidines

Catalyst:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione

Cas No:

1256245-86-9

Associated Product from Buchler GmbH:

Cinchonidine Base

Cas No:

485-71-2