Facile one-pot synthesis of cinchona alkaloid-based P,N ligands and their application to Pd-catalyzed asymmetric allylic alkylation.

DOI Number:

10.1016/j.tetasy.2008.10.030
Link to literature

Reaction Category:

Alkylation | Allylic Alkylation

MOP ID:

MOP_0000369

Educt:

(E)-1,3-diphenylallyl acetate, dimethyl malonate

Product:

dimethyl (R,E)-2-(1,3-diphenylallyl)malonate

Catalyst:

Di-μ-chlorobis(η3-2-propenyl)dipalladium, (8α,9R)-9-[[(4S,5S)-4,5-Diphenyl-1,3,2-dioxaphospholan-2-yl]oxy]cinchonan

Cas No:

1108188-23-3

Associated Product from Buchler GmbH:

Cinchondine Base

Cas No:

485-71-2