Efficient catalytic asymmetric alkylations. 1. Enantioselective synthesis of (+)-indacrinone via chiral phase-transfer catalysis.

DOI Number:

10.1021/ja00314a045
Link to literature

Reaction Category:

Alkylation | Alkylation

MOP ID:

MOP_0000369

Educt:

6,7-dichloro-5-methoxy-2-phenyl-2,3-dihydro-1H-inden-1-one, chloromethane

Product:

(S)-6,7-dichloro-5-methoxy-2-methyl-2-phenyl-2,3-dihydro-1H-inden-1-one

Catalyst:

(8α,9R)-9-hydroxy-1-[[4-(trifluoromethyl)phenyl]methyl]-Cinchonanium chloride

Cas No:

104761-88-8

Associated Product from Buchler GmbH:

Cinchonidine Base

Cas No:

485-71-2