Atropisomer synthesis, O/C-substituted 2′-hydroxy-3,4-dihydro-[1,1′-binaphthalen]-2(1H)-one, benzyl iodide, atropisomeric biaryls, (9S)-9-hydroxy-6′-methoxy-1-[(2,3,4-trifluorophenyl)methyl]-cinchonanium bromide, Quinidine Derivative by werner@buchler-gmbh.com | May 30, 2023
Bromination, 8‐Arylquinolines, N-bromoacetamide, 2,4,6-tribromo-3-(isoquinolin-1-yl)phenol, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]-urea, Quinidine Derivative by werner@buchler-gmbh.com | May 30, 2023
O-Alkylation, C/O-substituted 2′-hydroxy-3,4-dihydro-[1,1′-binaphthalen]-2(1H)-one, benzyl iodide, atropisomeric biaryls, (9S)-9-hydroxy-6′-methoxy-1-[(2,3,4-trifluorophenyl)methyl]-cinchonanium bromide, Quinidine Derivative by werner@buchler-gmbh.com | May 26, 2023
Trifluoromethylthiolation, beta-keto esters, N-trifluoromethylthiophthalimide, tert-butyl (S)-4-methyl-2-oxo-1-((trifluoromethyl)thio)cyclopent-3-ene-1-carboxylate, Quinidine Base by werner@buchler-gmbh.com | May 11, 2023
Desymmetrization, alkyne‐linked cyclohexanones, 1,2-disubstituted (1R,5S)-4-methylene-2-azabicyclo[3.3.1]nonan-6-one, silver(I) acetate, (S)-2-(diarylmethyl)pyrrolidine, N-(9R)-cinchonan-9-yl-2-(diphenylphosphino)-benzamide, Cinchonine Derivative by werner@buchler-gmbh.com | May 4, 2023