Enantioselective Squaramide-Catalyzed Trifluoromethylthiolation–Sulfur–Michael/Aldol Cascade Reaction: One-Pot Synthesis of CF3S-Containing Spiro Cyclopentanone–Thiochromanes.
DOI Number:
10.1021/acs.orglett.6b03846
Reaction Category:
Educt:
ethyl 4-ethoxy-2-oxocyclohex-3-ene-1-carboxylate, 1-((trifluoromethyl)thio)pyrrolidine-2,5-dione
Product:
ethyl (S)-4-ethoxy-2-oxo-1-((trifluoromethyl)thio)cyclohex-3-ene-1-carboxylate
Catalyst:
3-[[(8α,9S)-10,11-Dihydro-6′-methoxycinchonan-9-yl]amino]-4-[(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)amino]-3-cyclobutene-1,2-dione
Cas No:
1567990-06-0
Associated Product from Buchler GmbH:
Dihydroquinine Base
Cas No:
522-66-7