Spirocyclization, substituted ethyl (E)-2-(1-methyl-2-oxoindolin-3-ylidene)acetate, 1,4-dithiane-2,5-diol, substituted ethyl (2’S,3R,4’R)-4′-hydroxy-1-methyl-2-oxo-4′,5′-dihydro-2’H-spiro[indoline-3,3′-thiophene]-2′-carboxylate, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[(9R)-cinchonan-9-ylamino]-3- cyclobutene-1,2-dione, Cinchonine Derivative by werner@buchler-gmbh.com | Apr 13, 2023
Cross-coupling, 2-methyl-2,3-dihydro-1H-inden-1-one, aryl halides, 2-substituted (R)-2-methyl-2,3-dihydro-1H-inden-1-one, tris(dibenzylideneacetone)dipalladium(0), Quinine Base by werner@buchler-gmbh.com | Mar 23, 2023
Michael Addition, 2-(4-nitrophenyl)-1-(1H-pyrazol-1-yl)ethan-1-one, (E)-(2-nitrovinyl)benzene, (2R,3S)-4-nitro-2-(4-nitrophenyl)-3-phenyl-1-(1H-pyrazol-1-yl)butan-1-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)- 10,11-dihydro-6′-methoxycinchonan-9-yl]-Urea, Dihydroquinine Derivative by werner@buchler-gmbh.com | Mar 22, 2023
vinylogous Mannich reaction, tert-butyl ((3-chlorophenyl)(phenylsulfonyl)methyl)carbamate, 2-(thiochroman-4-ylidene)malononitrile, tert-butyl ((S)-(3-chlorophenyl)((S)-4-(dicyanomethylene)thiochroman-3-yl)methyl)carbamate, (8α,9R)-9-hydroxy-1-(phenylmethyl)-cinchonanium chloride, Cinchonidine Derivative by werner@buchler-gmbh.com | Mar 20, 2023
Henry reaction, aldehydes, nitroalkanes, beta-nitroalcohols, 2,4-bis(1,1-dimethylethyl)-6-[(E)-[[(8α,9S)-6′-methoxycinchonan-9-yl]imino]methyl]-phenol, Quinine Derivative by werner@buchler-gmbh.com | Mar 7, 2023