Michael Addition, ethyl 2-cyano-2-(1H-pyrrol-1-yl)acetate, 2-chloroacrylonitrile, ethyl 2,4-dicyano-2-(1H-pyrrol-1-yl)butanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative by werner@buchler-gmbh.com | Mar 20, 2026
Spirocyclization, ethyl (E)-2-(5-methyl-2-oxobenzofuran-3(2H)-ylidene)acetate, N-protected 5-fluoro-3-((4-oxo-4H-chromen-3-yl)methyl)indolin-2-one, spirocyclic compound, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative by werner@buchler-gmbh.com | Mar 20, 2026
Epoxidation, (E)-3-(2-fluorophenyl)-1-phenylprop-2-en-1-one, hydrogen peroxide, ((2S,3R)-3-(2-fluorophenyl)oxiran-2-yl)(phenyl)methanone, (8α,9R)-(8′′α,9′′R)-1,1′′-[[2,2-bis[[4-[[(8α,9R)-9-hydroxy-6′-methoxycinchonanium-1-yl]methyl]phenoxy]methyl]-1,3-propanediyl]bis(oxy-4,1-phenylenemethylene)]bis[9-hydroxy-6′-methoxy-cinchonanium bromide, Quinine Derivative by werner@buchler-gmbh.com | Mar 19, 2026
Oxa-Michael, substituted 3-(3-chloro-5-(trifluoromethyl)phenyl)-4,4,4-trifluoro-1-(naphthalen-1-yl)but-2-en-1-one, hydroxylamine, isoxazoline compound, (8α,9R)-9-hydroxy-6′-methoxy-1-[[3,4,5-tris(phenylmethoxy)phenyl]methyl]-cinchonanium chloride, Quinine Derivative by werner@buchler-gmbh.com | Mar 19, 2026
Oxa-Michael, tert-butyl (E)-5′-(3-(3,5-dichlorophenyl)-4,4,4-trifluorobut-2-enoyl)-3’H-spiro[azetidine-3,1′-isobenzofuran]-1-carboxylate, hydroxylamine, spirocyclic isooxazolines, (8α,9R)-1-(9-acridinylmethyl)-9-hydroxy-6′-methoxy-cinchonanium bromide, Quinine Derivative by werner@buchler-gmbh.com | Mar 18, 2026
