Isoxazoline Cyclization, substituted 4,4,4-trifluoro-1,3-diphenylbut-2-en-1-one, hydroxylamine, 4-((S)-5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-((R)-2-ethyl-3-oxoisoxazolidin-4-yl)-2-methylbenzamide, (8α,9R)-(8′′α,9′′R)-1,1′′-[(2,3,5,6-tetrafluoro-1,4-phenylene)bis(methylene)]bis[9-hydroxy-6′-methoxy-cinchonanium bromide, Quinine Derivative by werner@buchler-gmbh.com | Mar 25, 2026
Isoxazoline Cyclization, substituted 4,4,4-trifluoro-1,3-diphenylbut-2-en-1-one, hydroxylamine, (R)-3-(5-bromo-4-methylthiophen-2-yl)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazole, N-[3,5-bis(tert-butyl)benzyl]-quininium Bromide, Quinine Derivative by werner@buchler-gmbh.com | Mar 25, 2026
Michael Addition, ethyl 2-cyano-2-(1H-pyrrol-1-yl)acetate, 2-chloroacrylonitrile, ethyl 2,4-dicyano-2-(1H-pyrrol-1-yl)butanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative by werner@buchler-gmbh.com | Mar 20, 2026
Spirocyclization, ethyl (E)-2-(5-methyl-2-oxobenzofuran-3(2H)-ylidene)acetate, N-protected 5-fluoro-3-((4-oxo-4H-chromen-3-yl)methyl)indolin-2-one, spirocyclic compound, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative by werner@buchler-gmbh.com | Mar 20, 2026
Epoxidation, (E)-3-(2-fluorophenyl)-1-phenylprop-2-en-1-one, hydrogen peroxide, ((2S,3R)-3-(2-fluorophenyl)oxiran-2-yl)(phenyl)methanone, (8α,9R)-(8′′α,9′′R)-1,1′′-[[2,2-bis[[4-[[(8α,9R)-9-hydroxy-6′-methoxycinchonanium-1-yl]methyl]phenoxy]methyl]-1,3-propanediyl]bis(oxy-4,1-phenylenemethylene)]bis[9-hydroxy-6′-methoxy-cinchonanium bromide, Quinine Derivative by werner@buchler-gmbh.com | Mar 19, 2026
