Any hydrocarbon or heterocycle with 4n+2 electrons in a fully conjugated cyclic π system is considered to be an...
Buchler Glossary
Wolff Rearrangement
The Wolff Rearrangement allows the generation of ketenes from α-diazoketones. During this reaction an α-diazocarbonyl compound is converted into a ketene by loss of dinitrogen with accompanying 1,2-rearrangement.
Wolff Rearrangement examples catalyzed by cinchona alkaloid derivatives can be found in our free of charge Chiral Catalyst Search.
Example from Literature
Evolution of a Strategy for the Enantioselective Total Synthesis of (+)-Psiguadial B. (Chapman et al.; J. Org. Chem. 2018, 83, 11, 6066-6085.)
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