Michael Addition, diethyl 2-((2,2,2-trifluoroethyl)imino)malonate, nitroalkenes, 4-substituted diethyl (3R,5R)-3-nitro-5-(trifluoromethyl)pyrrolidine-2,2-dicarboxylate, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCascade reaction, Michael, Michael Addition Spirocyclization, 3-alkylidene oxindoles, isatins, spirocyclic indoles, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAldol, Cascade reaction, Spirocyclization, Vinylogous Aldol Spirocyclization, 3-alkylidene oxindoles, isatins, spirocyclic indoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAldol, Cascade reaction, Spirocyclization, Vinylogous Aldol Cyclization, diethyl (E)-2-((2-hydroxybenzylidene)amino)malonate, benzyl (E)-2-oxo-4-phenylbut-3-enoate, chromenopyrrolidines, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCyclization, Cyclization, Further Cyclizations Cyclization, 2-formylbenzonitrile, diisopropyl malonate, 3-substituted isoindolinones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCyclization, Cyclization, Further Cyclizations Michael Addition, azlactones, o-hydroxy chalcones, (R)-2-((S)-1-(5-chloro-2-hydroxyphenyl)-3-(4-iodophenyl)-3-oxopropyl)-2,4-diphenyloxazol-5(2H)-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition Michael Addition, acetylaceton, β-nitrostyrene, 3-(2-nitro-1-phenylethyl)pentane-2,4-dione, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition Alkylation, N-protected 3-allylindolin-2-one, N-protected 1-ethoxy-3-phenylprop-2-yn-1-amine, pyrazoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAlkylation, Alkylation Mannich reaction, substituted 3-iminoindolin-2-one, substituted 2,4-dihydro-3H-pyrazol-3-one, pyrazoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMannich, Mannich Cyclization, (E)-N-(4-methoxybenzylidene)-4-methylbenzenesulfonamide, isocyanatomalonate diester, 2-imidazolidinones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCyclization, Cyclization, Further Cyclizations, Mannich, Mannich« Older Entries
Michael Addition, diethyl 2-((2,2,2-trifluoroethyl)imino)malonate, nitroalkenes, 4-substituted diethyl (3R,5R)-3-nitro-5-(trifluoromethyl)pyrrolidine-2,2-dicarboxylate, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCascade reaction, Michael, Michael Addition
Spirocyclization, 3-alkylidene oxindoles, isatins, spirocyclic indoles, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAldol, Cascade reaction, Spirocyclization, Vinylogous Aldol
Spirocyclization, 3-alkylidene oxindoles, isatins, spirocyclic indoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAldol, Cascade reaction, Spirocyclization, Vinylogous Aldol
Cyclization, diethyl (E)-2-((2-hydroxybenzylidene)amino)malonate, benzyl (E)-2-oxo-4-phenylbut-3-enoate, chromenopyrrolidines, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCyclization, Cyclization, Further Cyclizations
Cyclization, 2-formylbenzonitrile, diisopropyl malonate, 3-substituted isoindolinones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCyclization, Cyclization, Further Cyclizations
Michael Addition, azlactones, o-hydroxy chalcones, (R)-2-((S)-1-(5-chloro-2-hydroxyphenyl)-3-(4-iodophenyl)-3-oxopropyl)-2,4-diphenyloxazol-5(2H)-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition
Michael Addition, acetylaceton, β-nitrostyrene, 3-(2-nitro-1-phenylethyl)pentane-2,4-dione, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition
Alkylation, N-protected 3-allylindolin-2-one, N-protected 1-ethoxy-3-phenylprop-2-yn-1-amine, pyrazoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAlkylation, Alkylation
Mannich reaction, substituted 3-iminoindolin-2-one, substituted 2,4-dihydro-3H-pyrazol-3-one, pyrazoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMannich, Mannich
Cyclization, (E)-N-(4-methoxybenzylidene)-4-methylbenzenesulfonamide, isocyanatomalonate diester, 2-imidazolidinones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCyclization, Cyclization, Further Cyclizations, Mannich, Mannich
