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Cycloaddition, substituted dihydrofuran-2,5-dione, aldehydes, trimethylsilyldiazomethane, 2,3-disubstituted methyl 5-oxotetrahydrofuran-3-carboxylate, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxy-2′-phenylcinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine Derivative

Cyclization, Cycloaddition

Cycloaddition, cyclic anhydrides, ketones, (3S)-substituted (R)-1-oxoisochromane-4-carboxylic acid, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxy-2′-phenylcinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine Derivative

Cyclization, Cycloaddition

Deoxygenation, secondary alcohols, sulfones, sulfinates, 3,4-Bis[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine Derivative

Deoxygenation, Further reactions

Peroxidation, α,β-unsaturated nitroalkenes, (1-hydroperoxy-1-methoxyethyl)benzene, 1-substituted 1-hydroperoxy-2-nitroethane, N-[(8α,9S)-6′-Methoxycinchonan-9-yl]-3,5-bis(trifluoromethyl)benzenesulfonamide, Quinine Derivative

Further reactions, Peroxidation

Desymmetrization, hexahydroisobenzofuran-1,3-dione, methanol, (1S,2R)-2-(methoxycarbonyl)cyclohexane-1-carboxylic acid, N-[(8α,9S)-6′-Methoxycinchonan-9-yl]-3,5-bis(trifluoromethyl)benzenesulfonamide, Quinine Derivative

Desymmetrization

Desymmetrization, cyclic anhydrides, methanol, (1S,2R)-2-(methoxycarbonyl)cyclohexane-1-carboxylic acid, N-[(8α,9S)-6′-Methoxycinchonan-9-yl]-3,5-bis(trifluoromethyl)benzenesulfonamide, Quinine Derivative

Desymmetrization

Michael Addition, 1H‐Imidazol‐4(5H)‐ones, 4-methyl-4-((trimethylsilyl)oxy)pent-1-en-3-one, substituted 5-(4-hydroxy-4-methyl-3-oxopentyl)-2-(alkylthio)-1,5-dihydro-4H-imidazol-4-one, N-[3,5-bis(trifluoromethyl)phenyl]-3-[[2-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]-benzamide, Quinine Derivative

Michael, Michael Addition

Spirocyclization, alkenyloxindoles, alkene‐substituted 1,3‐diketones, polycyclic tetrahydroxanthone, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative

Cascade reaction, Spirocyclization

Amination, 2-bromo-N-phenylpropanamide, N-methylaniline, (S)-2-(methyl(phenyl)amino)-N-phenylpropanamide, copper iodide, N-[(S)-[(1S,2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]oct-2-yl](6-methoxy-4-quinolinyl)methyl]-8-quinolinesulfonamide, Quinine Derivative

alpha-Amination, Amination

Allylation, substituted N-(prop-2-yn-1-yl)formamide, substituted indoline-2,3-dione, substituted (R)-3-hydroxy-3-((S)-5-methylene-4,5-dihydrooxazol-4-yl)indolin-2-one, 3-[(3,5-dimethoxyphenyl)amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative

Alkylation, Allylation, Cyclization, Cyclization, Further Cyclizations

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