Chlorination, indole derived benzamides, 1,3-Dichloro-5,5-diphenyl-2,4-imidazolidinedione, substituted 1-((2R,3S)-3-chloro-2′-phenyl-4’H-spiro[indoline-2,5′-oxazol]-1-yl)ethan-1-one, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeChlorination, Spirocyclization Desymmetrization, C2-symmetric derivatives, 5-substituted cyclohexane-1,3-dione, decalin derivatives, (9S)-10,11-Dihydro-6′-methoxy-9-(9-phenanthrenyloxy)cinchonan, Dihydroquinidine DerivativeDesymmetrization Selenolactonization, 4-(4-fluorophenyl)pent-4-enoic acid, N-(Phenylseleno)phthalimide, (R)-5-(4-fluorophenyl)-5-((phenylselanyl)methyl)dihydrofuran-2(3H)-one, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeFurther reactions, Lactonization, Selenenylation Iodination, substituted 2-(prop-2-yn-1-yl)pent-4-ynoic acid, N-iodosuccinimide, highly substituted enol lactones, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeDesymmetrization, Iodination, Lactonization Spirocyclization, benzofurans, N-chlorophthalimide, substituted (2R,3S)-3-chloro-3H,4’H-spiro[benzofuran-2,5′-oxazole], 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeChlorination, Dearomatization, Further reactions, Spirocyclization Spirocyclization, substituted (E)-3-((2,2,2-trifluoroethyl)imino)indolin-2-one, 5‐alkenyl thiazolones, pyrrolidinyl spirooxindoles, (9S,9′′S)-9,9′′-[(2,5-diphenyl-4,6-pyrimidinediyl)bis(oxy)]bis[10,11-dihydro-6′-methoxy-cinchonan], Dihydroquinidine DerivativeSpirocyclization Chlorocyclization, alkeneamides, 1,3-dichloro-5,5-diphenylhydantoin, (5S,6R)-5-chloro-2,6-diphenyl-5,6-dihydro-4H-1,3-oxazine, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeChlorination, Cyclization, Cyclization, Further Cyclizations Mannich reaction, 4-benzyl-2-phenyloxazol-5(4H)-one, ethyl 2-((4-methylphenyl)sulfonamido)acrylate, α,β-diamino diacid derivatives, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeMannich, Mannich Atropisomer synthesis, (R)-2-acetylcyclopentan-1-one, N-(2-tert-butylphenyl) succinimides, (1R,1’S)-1′-acetyl-3-(2-(tert-butyl)-4-methoxyphenyl)-[1,1′-bi(cyclopentane)]-2,2′,4-trione, (9S,9′′S)-9,9′′-[(2,5-diphenyl-4,6-pyrimidinediyl)bis(oxy)] bis[10,11-dihydro-6′-methoxy-cinchonan], Dihydroquinidine DerivativeAtropisomer synthesis Aziridination, alkenyl alcohols, 2,2,3,3,3-pentafluoropropyl sulfamate, 2,2,3,3,3-pentafluoropropyl (2R,3S)-2-(2-hydroxyethyl)-3-(4-(trifluoromethyl)phenyl)aziridine-1-sulfonate, rhodium(II,II) tetracarboxylate dimer, (1S,2R,4S,5R)-5-ethyl-2-((S)-hydroxy(6-methoxyquinolin-4-yl)methyl)-1-((3,3”,5,5”-tetrakis(triethylsilyl)-[1,1′:3′,1”-terphenyl]-5′-yl)methyl)quinuclidin-1-ium, Dihydroquinidine DerivativeAziridination« Older EntriesNext Entries »
Chlorination, indole derived benzamides, 1,3-Dichloro-5,5-diphenyl-2,4-imidazolidinedione, substituted 1-((2R,3S)-3-chloro-2′-phenyl-4’H-spiro[indoline-2,5′-oxazol]-1-yl)ethan-1-one, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeChlorination, Spirocyclization
Desymmetrization, C2-symmetric derivatives, 5-substituted cyclohexane-1,3-dione, decalin derivatives, (9S)-10,11-Dihydro-6′-methoxy-9-(9-phenanthrenyloxy)cinchonan, Dihydroquinidine DerivativeDesymmetrization
Selenolactonization, 4-(4-fluorophenyl)pent-4-enoic acid, N-(Phenylseleno)phthalimide, (R)-5-(4-fluorophenyl)-5-((phenylselanyl)methyl)dihydrofuran-2(3H)-one, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeFurther reactions, Lactonization, Selenenylation
Iodination, substituted 2-(prop-2-yn-1-yl)pent-4-ynoic acid, N-iodosuccinimide, highly substituted enol lactones, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeDesymmetrization, Iodination, Lactonization
Spirocyclization, benzofurans, N-chlorophthalimide, substituted (2R,3S)-3-chloro-3H,4’H-spiro[benzofuran-2,5′-oxazole], 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeChlorination, Dearomatization, Further reactions, Spirocyclization
Spirocyclization, substituted (E)-3-((2,2,2-trifluoroethyl)imino)indolin-2-one, 5‐alkenyl thiazolones, pyrrolidinyl spirooxindoles, (9S,9′′S)-9,9′′-[(2,5-diphenyl-4,6-pyrimidinediyl)bis(oxy)]bis[10,11-dihydro-6′-methoxy-cinchonan], Dihydroquinidine DerivativeSpirocyclization
Chlorocyclization, alkeneamides, 1,3-dichloro-5,5-diphenylhydantoin, (5S,6R)-5-chloro-2,6-diphenyl-5,6-dihydro-4H-1,3-oxazine, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeChlorination, Cyclization, Cyclization, Further Cyclizations
Mannich reaction, 4-benzyl-2-phenyloxazol-5(4H)-one, ethyl 2-((4-methylphenyl)sulfonamido)acrylate, α,β-diamino diacid derivatives, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeMannich, Mannich
Atropisomer synthesis, (R)-2-acetylcyclopentan-1-one, N-(2-tert-butylphenyl) succinimides, (1R,1’S)-1′-acetyl-3-(2-(tert-butyl)-4-methoxyphenyl)-[1,1′-bi(cyclopentane)]-2,2′,4-trione, (9S,9′′S)-9,9′′-[(2,5-diphenyl-4,6-pyrimidinediyl)bis(oxy)] bis[10,11-dihydro-6′-methoxy-cinchonan], Dihydroquinidine DerivativeAtropisomer synthesis
Aziridination, alkenyl alcohols, 2,2,3,3,3-pentafluoropropyl sulfamate, 2,2,3,3,3-pentafluoropropyl (2R,3S)-2-(2-hydroxyethyl)-3-(4-(trifluoromethyl)phenyl)aziridine-1-sulfonate, rhodium(II,II) tetracarboxylate dimer, (1S,2R,4S,5R)-5-ethyl-2-((S)-hydroxy(6-methoxyquinolin-4-yl)methyl)-1-((3,3”,5,5”-tetrakis(triethylsilyl)-[1,1′:3′,1”-terphenyl]-5′-yl)methyl)quinuclidin-1-ium, Dihydroquinidine DerivativeAziridination
