Aza-Michael Addition, α,β-unsaturated ketones, 2-pyrazolin-5-ones, β-(3-hydroxypyrazol-1-yl) ketones, benzoic acid, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeAza-Michael, Michael Addition Kinetic resolution, 5-subsituted 2-((trimethylsilyl)methyl)-2H-tetrazole, substituted 2-(fluoromethyl)acrylate, (tetrazolyl) methyl-containing acrylates, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeKinetic resolution, Resolution [4+2] Cycloaddition, 2‐sulfonylalkyl phenols, allenic esters, benzyl (R,E)-2-(6-methoxy-4-phenyl-3,4-dihydro-2H-benzo[h]chromen-2-ylidene)acetate, (9S)-10,11-Dihydro-6′-methoxy-9-(9-anthracenylmethyloxy)cinchonan, Dihydroquinidine Derivative[4+2]-Cycloaddition, Cycloaddition Michael Addition, enones, nitroalkanes, nitroketones, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeMichael, Michael Addition Atropisomer Synthesis, 1,3-dimethyl-5-tosylbenzo[k]phenanthridin-6(5H)-one, 3-oxo-3-(pyrrolidin-1-yl)propanenitrile, N-(3,5-dimethyl-2-(2-(4-(pyrrolidine-1-carbonyl)oxazol-5-yl)naphthalen-1-yl)phenyl)-4-methylbenzenesulfonamide, silver carbonate, 3-[(1,1-Dimethylethyl)amino]-4-[[(8α,9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeAtropisomer synthesis, C-N bond cleavage, Further reactions Cyanation, α-ketophosphonates, trimethylsilyl cyanide, tertiary α-hydroxy phosphonates, N-[(8α,9S)-6′-Methoxycinchonan-9-yl]-N′-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-thiourea, Quinine DerivativeCyanation Sulfenylation, azlactones, N-(sulfanyl) succinimides, α-sulfenylated azlactones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeSulfenylation Desymmetrization, (3aR,7aS)-3a,4,7,7a-tetrahydroisobenzofuran-1,3-dione, methanol, (1S,6R)-6-(methoxycarbonyl)cyclohex-3-ene-1-carboxylic acid, 4-ethenyl-N-[(S)-[(1S,2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]oct-2-yl](6-methoxy-4-quinolinyl)methyl]-benzenesulfonamide, Quinine DerivativeDesymmetrization Bromohydroxylation, N-bromosuccinimide, phenylboronic acid, 2-(3-methoxyphenyl)prop-2-en-1-ol, (S)-3-bromo-2-(3-methoxyphenyl)propane-1,2-diol, 4-Methoxy-N-[(8α,9S)-6′-methoxycinchonan-9-yl]benzenesulfonamide, Quinine DerivativeBromination, Bromohydroxylation Cyclopropantion, 3-chloro-1-ethylindolin-2-one, 2-benzylidene-1H-indene-1,3(2H)-dione, (2’R,3’S)-1”-ethyl-3′-phenyldispiro[indene-2,1′-cyclopropane-2′,3”-indoline]-1,2”,3-trione, N-[(1R,2S)-2,3-dihydro-2-hydroxy-1H-inden-1-yl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl] thiourea, Quinine DerivativeCyclopropanation, Spirocyclization« Older EntriesNext Entries »
Aza-Michael Addition, α,β-unsaturated ketones, 2-pyrazolin-5-ones, β-(3-hydroxypyrazol-1-yl) ketones, benzoic acid, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeAza-Michael, Michael Addition
Kinetic resolution, 5-subsituted 2-((trimethylsilyl)methyl)-2H-tetrazole, substituted 2-(fluoromethyl)acrylate, (tetrazolyl) methyl-containing acrylates, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeKinetic resolution, Resolution
[4+2] Cycloaddition, 2‐sulfonylalkyl phenols, allenic esters, benzyl (R,E)-2-(6-methoxy-4-phenyl-3,4-dihydro-2H-benzo[h]chromen-2-ylidene)acetate, (9S)-10,11-Dihydro-6′-methoxy-9-(9-anthracenylmethyloxy)cinchonan, Dihydroquinidine Derivative[4+2]-Cycloaddition, Cycloaddition
Michael Addition, enones, nitroalkanes, nitroketones, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeMichael, Michael Addition
Atropisomer Synthesis, 1,3-dimethyl-5-tosylbenzo[k]phenanthridin-6(5H)-one, 3-oxo-3-(pyrrolidin-1-yl)propanenitrile, N-(3,5-dimethyl-2-(2-(4-(pyrrolidine-1-carbonyl)oxazol-5-yl)naphthalen-1-yl)phenyl)-4-methylbenzenesulfonamide, silver carbonate, 3-[(1,1-Dimethylethyl)amino]-4-[[(8α,9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeAtropisomer synthesis, C-N bond cleavage, Further reactions
Cyanation, α-ketophosphonates, trimethylsilyl cyanide, tertiary α-hydroxy phosphonates, N-[(8α,9S)-6′-Methoxycinchonan-9-yl]-N′-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-thiourea, Quinine DerivativeCyanation
Sulfenylation, azlactones, N-(sulfanyl) succinimides, α-sulfenylated azlactones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeSulfenylation
Desymmetrization, (3aR,7aS)-3a,4,7,7a-tetrahydroisobenzofuran-1,3-dione, methanol, (1S,6R)-6-(methoxycarbonyl)cyclohex-3-ene-1-carboxylic acid, 4-ethenyl-N-[(S)-[(1S,2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]oct-2-yl](6-methoxy-4-quinolinyl)methyl]-benzenesulfonamide, Quinine DerivativeDesymmetrization
Bromohydroxylation, N-bromosuccinimide, phenylboronic acid, 2-(3-methoxyphenyl)prop-2-en-1-ol, (S)-3-bromo-2-(3-methoxyphenyl)propane-1,2-diol, 4-Methoxy-N-[(8α,9S)-6′-methoxycinchonan-9-yl]benzenesulfonamide, Quinine DerivativeBromination, Bromohydroxylation
Cyclopropantion, 3-chloro-1-ethylindolin-2-one, 2-benzylidene-1H-indene-1,3(2H)-dione, (2’R,3’S)-1”-ethyl-3′-phenyldispiro[indene-2,1′-cyclopropane-2′,3”-indoline]-1,2”,3-trione, N-[(1R,2S)-2,3-dihydro-2-hydroxy-1H-inden-1-yl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl] thiourea, Quinine DerivativeCyclopropanation, Spirocyclization
