Spirocyclization, substituted 3-(4-oxo-4,5,6,7-tetrahydrobenzofuran-3-yl)indolin-2-one, (E)-(2-nitrovinyl)benzene, spirooxindoles, (8α,9R)-10,11-dihydro-6′-methoxy-11-phenyl-cinchonan-9-ol, Quinine DerivativeCascade reaction, Spirocyclization Spirocyclization, substituted indoline-2,3-dione, substituted phenylmethanamine, nitroalkenes, substituted 4′-nitrospiro[indoline-3,2′-pyrrolidin]-2-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCascade reaction, Spirocyclization Dearomatization, 1-(3-methyl-3-tosylbut-1-yn-1-yl)naphthalen-2-ol, N-bromophthalimide, (3aR,7aR)-1-bromo-2,2,6-trimethyl-2H,7aH-benzo[a]thieno[2,3-l]xanthene 3,3-dioxide, (2S)-2-[[2-[[3,5-bis(trifluoromethyl)phenyl]amino]-4,5-dioxo-1-cyclobuten-1-yl]amino]-N-[(9S)-6′-methoxycinchonan-9-yl]-3-methyl-butanamide, Quinine DerivativeCyclization, Cyclization, Dearomatization, Further Cyclizations, Further reactions Epoxidation, 2-methylene-1,3-diketones, tert-butyl hydroperoxide, terminal epoxides, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeEpoxidation Spirocyclization, nonactivated arenes, N-bromosuccinimide, 16-bromo-11-chloro-16,16a-dihydro-7aH-benzo[a]indeno[1,2-l]xanthene, N-[(8α,9S)-6′-Methoxycinchonan-9-yl]- 4-(trifluoromethyl)benzamide, Quinine DerivativeCycloaddition, Dearomatization, Diels-Alder reaction, Further reactions, Spirocyclization Sulfa-Michael Addition, trans‐chalcones, thiols, substituted (R)-3-(alkylthio)-1,3-diphenylpropan-1-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMichael Addition, Sulfa-Michael, Sulfa-Michael Addition Atropisomer Synthesis, 1-(3,3-dimethylbut-1-yn-1-yl)naphthalen-2-ol, 4-methylbenzenethiol, (E)-1-(3,3-dimethyl-1-(p-tolylthio)but-1-en-1-yl)naphthalen-2-ol, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine DerivativeAtropisomer synthesis [4+2] Cycloaddition, 1-azaaurones, deconjugated butenolides, substituted 4,5-dihydropyrano[3,2-b]indol-2(3H)-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative[4+2]-Cycloaddition, Cycloaddition Cyclization, arylalcohols, deconjugated butenolides, 2-chromanones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAddition, Cyclization, Cyclization, Further Cyclizations Michael Addition, cyclic ketones, (ethene-1,1-diyldisulfonyl)dibenzene, α‐branched ketone dienolates, 3-[(1,1-dimethylethyl)amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition« Older EntriesNext Entries »
Spirocyclization, substituted 3-(4-oxo-4,5,6,7-tetrahydrobenzofuran-3-yl)indolin-2-one, (E)-(2-nitrovinyl)benzene, spirooxindoles, (8α,9R)-10,11-dihydro-6′-methoxy-11-phenyl-cinchonan-9-ol, Quinine DerivativeCascade reaction, Spirocyclization
Spirocyclization, substituted indoline-2,3-dione, substituted phenylmethanamine, nitroalkenes, substituted 4′-nitrospiro[indoline-3,2′-pyrrolidin]-2-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCascade reaction, Spirocyclization
Dearomatization, 1-(3-methyl-3-tosylbut-1-yn-1-yl)naphthalen-2-ol, N-bromophthalimide, (3aR,7aR)-1-bromo-2,2,6-trimethyl-2H,7aH-benzo[a]thieno[2,3-l]xanthene 3,3-dioxide, (2S)-2-[[2-[[3,5-bis(trifluoromethyl)phenyl]amino]-4,5-dioxo-1-cyclobuten-1-yl]amino]-N-[(9S)-6′-methoxycinchonan-9-yl]-3-methyl-butanamide, Quinine DerivativeCyclization, Cyclization, Dearomatization, Further Cyclizations, Further reactions
Epoxidation, 2-methylene-1,3-diketones, tert-butyl hydroperoxide, terminal epoxides, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeEpoxidation
Spirocyclization, nonactivated arenes, N-bromosuccinimide, 16-bromo-11-chloro-16,16a-dihydro-7aH-benzo[a]indeno[1,2-l]xanthene, N-[(8α,9S)-6′-Methoxycinchonan-9-yl]- 4-(trifluoromethyl)benzamide, Quinine DerivativeCycloaddition, Dearomatization, Diels-Alder reaction, Further reactions, Spirocyclization
Sulfa-Michael Addition, trans‐chalcones, thiols, substituted (R)-3-(alkylthio)-1,3-diphenylpropan-1-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMichael Addition, Sulfa-Michael, Sulfa-Michael Addition
Atropisomer Synthesis, 1-(3,3-dimethylbut-1-yn-1-yl)naphthalen-2-ol, 4-methylbenzenethiol, (E)-1-(3,3-dimethyl-1-(p-tolylthio)but-1-en-1-yl)naphthalen-2-ol, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine DerivativeAtropisomer synthesis
[4+2] Cycloaddition, 1-azaaurones, deconjugated butenolides, substituted 4,5-dihydropyrano[3,2-b]indol-2(3H)-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative[4+2]-Cycloaddition, Cycloaddition
Cyclization, arylalcohols, deconjugated butenolides, 2-chromanones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAddition, Cyclization, Cyclization, Further Cyclizations
Michael Addition, cyclic ketones, (ethene-1,1-diyldisulfonyl)dibenzene, α‐branched ketone dienolates, 3-[(1,1-dimethylethyl)amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition
