Atropisomer synthesis, diaryl ethers, nitromethane, diaryl ethers, (8α,9S)-1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-9-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-6′-methoxy-cinchonanium bromide, Quinine DerivativeAlkylation, Alkylation, Atropisomer synthesis Spirocyclization, 4-bromo-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, N-((E)-2-((Z)-4-methoxybenzylidene)benzofuran-3(2H)-ylidene)-4-methylbenzenesulfonamide, N-((2R,4’R,E)-4′-(4-methoxyphenyl)-3′-methyl-1′-phenyl-1′,4′-dihydro-3H-spiro[benzofuran-2,5′-furo[2,3-c]pyrazol]-3-ylidene)-4-methylbenzenesulfonamide, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative[3+2] Annulation, Cyclization, Further Cyclizations, Spirocyclization Aza-Michael Addition, nitroalkenes, tosyl protected δ‐amino-α,β-unsaturated ketones, trisubstituted pyrrolidines, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeAza-Michael, Michael Addition Aza-Michael Addition, diamino-α,β-unsaturated ketones, 2,5,5-trisubstituted piperidines, (8α,9S)-10,11-Dihydro-6′-methoxycinchonan-9-amine, Dihydroquinine DerivativeAza-Michael, Intramolecular Aza-Michael, Michael Addition Aza-Michael Addition, vinyl sulfonamides, bicyclic δ‐sultams, (8α,9S)-10,11-Dihydro-6′-methoxycinchonan-9-amine, Dihydroquinine DerivativeAza-Michael, Intramolecular Aza-Michael, Michael Addition [3+2]-Annulation, substituted tert-butyl (3-cyano-1,1,1-trifluorobut-3-en-2-yl) carbonate, substituted benzo[d]isothiazole-3-carboxylate 1,1-dioxide, substituted (9bS)-2-cyano-1-(trifluoromethyl)benzo[d]pyrrolo[1,2-b]isothiazole-9b(1H)-carboxylate 5,5-dioxide, (8α,9R)-(8′′α,9′′R)-9,9′′-[(2,5-Diphenyl-4,6-pyrimidinediyl)bis(oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine Derivative[3+2] Annulation, Cyclization, Further Cyclizations Amination, amides, α-diazoketones, chiral amides, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea, Dihydroquinine Derivativealpha-Amination, Amination Cyclopropanation, oxindoles, α-chloro-β-diketones, substituted tert-butyl 2′-oxospiro[cyclopropane-1,3′-indoline]-1′-carboxylate, N-[2,6-bis(1-methylethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-thiourea, Dihydroquinine DerivativeCyclopropanation, Spirocyclization Cyclopropanation, oxindoles, bromonitroalkanes, substituted tert-butyl 2-nitro-2′-oxospiro[cyclopropane-1,3′-indoline]-1′-carboxylate, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeCyclopropanation, Spirocyclization Fluorination, 3-functionalized 2-oxindoles, N-fluorbenzolsulfonimid, 3-functionalized 3-fluoro-2-oxindoles, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-N′-tricyclo[3.3.1.13,7]dec-1-yl-urea, Quinine DerivativeFluorination, Fluorination« Older EntriesNext Entries »
Atropisomer synthesis, diaryl ethers, nitromethane, diaryl ethers, (8α,9S)-1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-9-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-6′-methoxy-cinchonanium bromide, Quinine DerivativeAlkylation, Alkylation, Atropisomer synthesis
Spirocyclization, 4-bromo-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, N-((E)-2-((Z)-4-methoxybenzylidene)benzofuran-3(2H)-ylidene)-4-methylbenzenesulfonamide, N-((2R,4’R,E)-4′-(4-methoxyphenyl)-3′-methyl-1′-phenyl-1′,4′-dihydro-3H-spiro[benzofuran-2,5′-furo[2,3-c]pyrazol]-3-ylidene)-4-methylbenzenesulfonamide, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative[3+2] Annulation, Cyclization, Further Cyclizations, Spirocyclization
Aza-Michael Addition, nitroalkenes, tosyl protected δ‐amino-α,β-unsaturated ketones, trisubstituted pyrrolidines, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeAza-Michael, Michael Addition
Aza-Michael Addition, diamino-α,β-unsaturated ketones, 2,5,5-trisubstituted piperidines, (8α,9S)-10,11-Dihydro-6′-methoxycinchonan-9-amine, Dihydroquinine DerivativeAza-Michael, Intramolecular Aza-Michael, Michael Addition
Aza-Michael Addition, vinyl sulfonamides, bicyclic δ‐sultams, (8α,9S)-10,11-Dihydro-6′-methoxycinchonan-9-amine, Dihydroquinine DerivativeAza-Michael, Intramolecular Aza-Michael, Michael Addition
[3+2]-Annulation, substituted tert-butyl (3-cyano-1,1,1-trifluorobut-3-en-2-yl) carbonate, substituted benzo[d]isothiazole-3-carboxylate 1,1-dioxide, substituted (9bS)-2-cyano-1-(trifluoromethyl)benzo[d]pyrrolo[1,2-b]isothiazole-9b(1H)-carboxylate 5,5-dioxide, (8α,9R)-(8′′α,9′′R)-9,9′′-[(2,5-Diphenyl-4,6-pyrimidinediyl)bis(oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine Derivative[3+2] Annulation, Cyclization, Further Cyclizations
Amination, amides, α-diazoketones, chiral amides, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea, Dihydroquinine Derivativealpha-Amination, Amination
Cyclopropanation, oxindoles, α-chloro-β-diketones, substituted tert-butyl 2′-oxospiro[cyclopropane-1,3′-indoline]-1′-carboxylate, N-[2,6-bis(1-methylethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-thiourea, Dihydroquinine DerivativeCyclopropanation, Spirocyclization
Cyclopropanation, oxindoles, bromonitroalkanes, substituted tert-butyl 2-nitro-2′-oxospiro[cyclopropane-1,3′-indoline]-1′-carboxylate, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeCyclopropanation, Spirocyclization
Fluorination, 3-functionalized 2-oxindoles, N-fluorbenzolsulfonimid, 3-functionalized 3-fluoro-2-oxindoles, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-N′-tricyclo[3.3.1.13,7]dec-1-yl-urea, Quinine DerivativeFluorination, Fluorination
