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Cacade reaction, 1,1-Dimethylethyl 2,3-dihydro-1-oxo-1H-indene-2-carboxylates, (Ethenylselenonyl)benzene, (2′S)-4,5-Dihydrospiro[furan-3(2H),2′-[2H]indene]-1′,2(3′H)-diones, (8α,9R)-9-(1-Phenanthrenyloxy)cinchonan-6′-ol, Cupreine Derivative

Cascade reaction, Michael Addition, Spirocyclization

gamma-Alkylation, alpha,beta unsaturated aldehydes, bis(4-(dimethylamino)phenyl)methanol, gamma-alkylated alpha,beta unsaturated aldehydes, 2-[[(8α,9S)-9-Aminocinchonan-6′-yl]oxy]acetic acid, Cupreine Derivative

Alkylation, gamma-Alkylation

Cyclization, (E)-6-hydroxy-1-substituted-hex-2-en-1-one, (R)-1-substituted-2-(tetrahydrofuran-2-yl)ethan-1-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Cyclization, Further Cyclizations, Intramolecular cyclization

Spirocyclization, substituted indolin-2-one, substituted indoline-2,3-dione, spirooxindole δ‐lactones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Cascade reaction, Spirocyclization

Amination, 1,2,3,4-tetrahydro-1-oxo-N-phenyl-2-naphthalenecarbothioamide, diisopropyl azodicarboxylate, diisopropyl (R,Z)-1-oxo-5′-(phenylimino)-3,4-dihydro-1H-spiro[naphthalene-2,4′-[1,2,3]thiadiazolidine]-2′,3′-dicarboxylate, Cupreine Base

Amination, Spirocyclization

Friedel-Crafts reaction, isatins, indoles, 3-Indolyl-3-hydroxy-2-oxindoles, Cupreine Base

Friedel-Crafts, Friedel-Crafts reaction

Aldol reaction, N-benzyl isatins, rifluoromethyl α-fluorinated gem-diols, 3-hydroxy oxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Aldol, Aldol

Cyclopropanation, α,β-unsaturated nitroalkenes, dimethyl 2-bromomalonate, nitrocyclopropanes, Cupreine Base

Cyclopropanation

Alkylation, 6,7-dichloro-5-methoxy-2-phenyl-2,3-dihydro-1H-inden-1-one, chloromethane, (S)-6,7-dichloro-5-methoxy-2-methyl-2-phenyl-2,3-dihydro-1H-inden-1-one, (8α,9R)-9-hydroxy-1-[[4-(trifluoromethyl)phenyl]methyl]-Cinchonanium chloride, Cinchonidine Derivative

Alkylation, Alkylation

Michael Addition, Diethyl P-(2-oxo-2-phenylethyl)phosphonate, 1-Methoxy-2-[(1E)-2-nitroethenyl]benzene, Diethyl P-[(1R,2R)-1-benzoyl-2-(2-methoxyphenyl)-3-nitropropyl]phosphonate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9R)-cinchonan-9-ylthiourea, Cinchonidine Derivative

Michael, Michael Addition

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