Cascade reaction, ethyl (E)-3-(((E)-3-(furan-2-yl)-2-nitroallyl)oxy)acrylate, ethyl (3S,4R)-4-(furan-2-yl)-3-nitro-3,4-dihydro-2H-pyran-5-carboxylate, 3-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-4-[(4-nitrophenyl)amino]-3-cyclobutene-1,2-dione, Quinine DerivativeCascade reaction Michael Addition, 3‐indolinone‐2‐carboxylates, maleimides, substituted (3S)-3-(3-oxoindolin-2-yl)pyrrolidine-2,5-dione, 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition Desymmetrization, pyrazolones, N-pyrazolyl maleimides, tri-N-heterocyclic scaffolds, (2S)-2-[[[[3,5-Bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-3,3-dimethylbutanamide, Quinine DerivativeDesymmetrization, Michael, Michael Addition Cyclization, N-(prop-2-yn-1-yl)pivalamide, ethyl (Z)-2-((tert-butoxycarbonyl)imino)-4-phenylbut-3-ynoate, ethyl (S)-2-((tert-butoxycarbonyl)amino)-5-(2-(tert-butyl)oxazol-5-yl)-4-phenylpenta-2,3-dienoate, 3-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-4-(phenylamino)-3-cyclobutene-1,2-dione, Quinine DerivativeCyclization, Cyclization, Further Cyclizations, Further reactions, Mannich, Mannich, Rearrangement Michael Addition, 2‐oxindole‐3‐carboxylate esters, 2‐phthalimido acrylates, ethyl (S)-3-((S)-2-(1,3-dioxoisoindolin-2-yl)-3-ethoxy-3-oxopropyl)-1-methyl-2-oxoindoline-3-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition Alkylation, N-(Diphenylmethylene)glycine 1-methyl-1-phenylethyl ester, Benzyl bromide, N-(Diphenylmethylene)-L-phenylalanine 1-methyl-1-phenylethyl ester, (8α,9R)-1-(9-anthracenylmethyl)-9-(2-propenyloxy)-Cinchonanium bromide, Cinchonidine DerivativeAlkylation, Alkylation Michael Addition, 3-aryloxindoles, nitroenynes, quaternary oxindoles, Bis(1-methylethyl) N-(8α,9S)-cinchonan-9-ylphosphoramidate, Cinchonidine DerivativeMichael, Michael Addition Mannich reaction, 3-(2,4-dioxopentan-3-yl)-1,1-dimethylurea, benzyl ((1Z,2E)-3-phenylallylidene)carbamate, benzyl (R,E)-(4-acetyl-4-(3,3-dimethylureido)-5-oxo-1-phenylhex-1-en-3-yl)carbamate, Cinchonidine BaseMannich, Mannich Dynamic kinetic resolution, 2,2,2-triphenyl-N-(p-tolylsulfinyl)acetamide, 2,2-dimethylpropan-1-ol, [S(R)]-4-methyl-N-(2,2,2-triphenylacetyl)-Benzenesulfinimidic acid 2,2-dimethylpropyl ester, Cinchonidine BaseDynamic Kinetic Resolution, Resolution Tandem Michael-Knoevenagel, 2-mercaptobenzaldehyde, diethyl 2-(2-methoxybenzylidene)malonate, substituted thiochromanes, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction« Older EntriesNext Entries »
Cascade reaction, ethyl (E)-3-(((E)-3-(furan-2-yl)-2-nitroallyl)oxy)acrylate, ethyl (3S,4R)-4-(furan-2-yl)-3-nitro-3,4-dihydro-2H-pyran-5-carboxylate, 3-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-4-[(4-nitrophenyl)amino]-3-cyclobutene-1,2-dione, Quinine DerivativeCascade reaction
Michael Addition, 3‐indolinone‐2‐carboxylates, maleimides, substituted (3S)-3-(3-oxoindolin-2-yl)pyrrolidine-2,5-dione, 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition
Desymmetrization, pyrazolones, N-pyrazolyl maleimides, tri-N-heterocyclic scaffolds, (2S)-2-[[[[3,5-Bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-3,3-dimethylbutanamide, Quinine DerivativeDesymmetrization, Michael, Michael Addition
Cyclization, N-(prop-2-yn-1-yl)pivalamide, ethyl (Z)-2-((tert-butoxycarbonyl)imino)-4-phenylbut-3-ynoate, ethyl (S)-2-((tert-butoxycarbonyl)amino)-5-(2-(tert-butyl)oxazol-5-yl)-4-phenylpenta-2,3-dienoate, 3-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-4-(phenylamino)-3-cyclobutene-1,2-dione, Quinine DerivativeCyclization, Cyclization, Further Cyclizations, Further reactions, Mannich, Mannich, Rearrangement
Michael Addition, 2‐oxindole‐3‐carboxylate esters, 2‐phthalimido acrylates, ethyl (S)-3-((S)-2-(1,3-dioxoisoindolin-2-yl)-3-ethoxy-3-oxopropyl)-1-methyl-2-oxoindoline-3-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition
Alkylation, N-(Diphenylmethylene)glycine 1-methyl-1-phenylethyl ester, Benzyl bromide, N-(Diphenylmethylene)-L-phenylalanine 1-methyl-1-phenylethyl ester, (8α,9R)-1-(9-anthracenylmethyl)-9-(2-propenyloxy)-Cinchonanium bromide, Cinchonidine DerivativeAlkylation, Alkylation
Michael Addition, 3-aryloxindoles, nitroenynes, quaternary oxindoles, Bis(1-methylethyl) N-(8α,9S)-cinchonan-9-ylphosphoramidate, Cinchonidine DerivativeMichael, Michael Addition
Mannich reaction, 3-(2,4-dioxopentan-3-yl)-1,1-dimethylurea, benzyl ((1Z,2E)-3-phenylallylidene)carbamate, benzyl (R,E)-(4-acetyl-4-(3,3-dimethylureido)-5-oxo-1-phenylhex-1-en-3-yl)carbamate, Cinchonidine BaseMannich, Mannich
Dynamic kinetic resolution, 2,2,2-triphenyl-N-(p-tolylsulfinyl)acetamide, 2,2-dimethylpropan-1-ol, [S(R)]-4-methyl-N-(2,2,2-triphenylacetyl)-Benzenesulfinimidic acid 2,2-dimethylpropyl ester, Cinchonidine BaseDynamic Kinetic Resolution, Resolution
Tandem Michael-Knoevenagel, 2-mercaptobenzaldehyde, diethyl 2-(2-methoxybenzylidene)malonate, substituted thiochromanes, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction