Oxa-Michael, substituted 2-(2-vinylcyclopropyl)phenol, ethyl (1S,1aS,2R,7bR)-2-(2-ethoxy-2-oxoethyl)-1,1a,2,7b-tetrahydrocyclopropa[c]chromene-1-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′- methoxycinchonan-9-yl]thiourea, Quinidine DerivativeMichael Addition, Oxa-Michael Addition Cyclopropanation, 4-nitro-5-styrylisoxazoles, bromomethylene diacetate, substituted (R)-2-(3-methyl-4-nitroisoxazol-5-yl)cyclopropane-1,1-diyl diacetate, (9S)-9-hydroxy-6′-methoxy-1-[(2-methoxyphenyl)methyl]-cinchonanium bromide, Quinidine DerivativeCyclopropanation Cascade reaction, ethyl (E)-4-mercaptobut-2-enoate, 3-nitrobenzothiophene, tetrahydrothiophenebenzothiophene, (αR)-α-[[[[3,5-Bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]benzenepropanamide, Quinine DerivativeCascade reaction, Michael, Michael Addition Umpolung, substituted 2,2,2-trifluoroethan-1-imine, α,β-unsaturated lactones, trifluoromethylated γ-amino lactones, (9S)-9-[(6-chloro-2,5-diphenyl-4-pyrimidinyl)oxy]-1-[[2′-(1,1-dimethylethoxy)[1,1′:3′,1′′-terphenyl]-5′-yl]methyl]-6′-methoxy-cinchonanium bromide, Quinidine DerivativeUmpolung Spirocyclization, (Z)-2-benzylidenebenzofuran-3(2H)-one, cyclopent-2-en-1-one, (1’R,2R,3’R,4’R)-3′-phenyl-3H-spiro[benzofuran-2,2′-bicyclo[2.2.1]heptane]-3,5′-dione, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine Derivative[4+2]-Cycloaddition, Cycloaddition, Diels-Alder reaction, Spirocyclization Bromination, 2-naphthols, N-bromophthalimide, substituted isopropyl (1R)-1-bromo-2-hydroxy-1,2-dihydronaphthalene-1-carboxylate, (9S)-9-[(4-chloro-1-phthalazinyl)oxy]-6′-methoxy-cinchonan, Quinidine DerivativeBromination, Dearomatization, Further reactions Amination, (1-bromoethyl)benzene, S,S-diphenylsulfoximine, (αR)-α-Methyl-N-(oxidodiphenyl-λ4-sulfanylidene)benzenemethanamine, (2-thiophenecarboxylato-κO2,κS1)-copper, 2-[bis[3,3′′,5,5′′-tetrakis(1,1-dimethylethyl)[1,1′:3′,1′′-terphenyl]-5′-yl]phosphino]-N-[(8α,9R)-6′-methoxycinchonan-9-yl]-benzamide, Quinidine DerivativeAmination Spirocyclization, indoles, spirocyclic compouns, (1S,2R,4S,5R)-1-(2-bromo-5-methoxybenzyl)-2-((S)-(1-(2-bromo-5-methoxybenzyl)-6-methoxyquinolin-1-ium-4-yl)(hydroxy)methyl)-5-vinylquinuclidin-1-ium bromide, Quinidine DerivativeSpirocyclization Cascade reaction, thioaryls, nitroolefines, carbonyl compounds, γ-sulfur-β-amino-α-hydroxy esters, (2S)-2-[[[[3,5-Bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-3,3-dimethylbutanamide, Quinine DerivativeCascade reaction Cascade reaction, 2-mercaptobenzaldehyde, β,γ-unsaturated α-ketoesters, isotetronic acid-fused thiochromanes, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCascade reaction« Older EntriesNext Entries »
Oxa-Michael, substituted 2-(2-vinylcyclopropyl)phenol, ethyl (1S,1aS,2R,7bR)-2-(2-ethoxy-2-oxoethyl)-1,1a,2,7b-tetrahydrocyclopropa[c]chromene-1-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′- methoxycinchonan-9-yl]thiourea, Quinidine DerivativeMichael Addition, Oxa-Michael Addition
Cyclopropanation, 4-nitro-5-styrylisoxazoles, bromomethylene diacetate, substituted (R)-2-(3-methyl-4-nitroisoxazol-5-yl)cyclopropane-1,1-diyl diacetate, (9S)-9-hydroxy-6′-methoxy-1-[(2-methoxyphenyl)methyl]-cinchonanium bromide, Quinidine DerivativeCyclopropanation
Cascade reaction, ethyl (E)-4-mercaptobut-2-enoate, 3-nitrobenzothiophene, tetrahydrothiophenebenzothiophene, (αR)-α-[[[[3,5-Bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]benzenepropanamide, Quinine DerivativeCascade reaction, Michael, Michael Addition
Umpolung, substituted 2,2,2-trifluoroethan-1-imine, α,β-unsaturated lactones, trifluoromethylated γ-amino lactones, (9S)-9-[(6-chloro-2,5-diphenyl-4-pyrimidinyl)oxy]-1-[[2′-(1,1-dimethylethoxy)[1,1′:3′,1′′-terphenyl]-5′-yl]methyl]-6′-methoxy-cinchonanium bromide, Quinidine DerivativeUmpolung
Spirocyclization, (Z)-2-benzylidenebenzofuran-3(2H)-one, cyclopent-2-en-1-one, (1’R,2R,3’R,4’R)-3′-phenyl-3H-spiro[benzofuran-2,2′-bicyclo[2.2.1]heptane]-3,5′-dione, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine Derivative[4+2]-Cycloaddition, Cycloaddition, Diels-Alder reaction, Spirocyclization
Bromination, 2-naphthols, N-bromophthalimide, substituted isopropyl (1R)-1-bromo-2-hydroxy-1,2-dihydronaphthalene-1-carboxylate, (9S)-9-[(4-chloro-1-phthalazinyl)oxy]-6′-methoxy-cinchonan, Quinidine DerivativeBromination, Dearomatization, Further reactions
Amination, (1-bromoethyl)benzene, S,S-diphenylsulfoximine, (αR)-α-Methyl-N-(oxidodiphenyl-λ4-sulfanylidene)benzenemethanamine, (2-thiophenecarboxylato-κO2,κS1)-copper, 2-[bis[3,3′′,5,5′′-tetrakis(1,1-dimethylethyl)[1,1′:3′,1′′-terphenyl]-5′-yl]phosphino]-N-[(8α,9R)-6′-methoxycinchonan-9-yl]-benzamide, Quinidine DerivativeAmination
Spirocyclization, indoles, spirocyclic compouns, (1S,2R,4S,5R)-1-(2-bromo-5-methoxybenzyl)-2-((S)-(1-(2-bromo-5-methoxybenzyl)-6-methoxyquinolin-1-ium-4-yl)(hydroxy)methyl)-5-vinylquinuclidin-1-ium bromide, Quinidine DerivativeSpirocyclization
Cascade reaction, thioaryls, nitroolefines, carbonyl compounds, γ-sulfur-β-amino-α-hydroxy esters, (2S)-2-[[[[3,5-Bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-3,3-dimethylbutanamide, Quinine DerivativeCascade reaction
Cascade reaction, 2-mercaptobenzaldehyde, β,γ-unsaturated α-ketoesters, isotetronic acid-fused thiochromanes, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCascade reaction
