Vinylogous Michael Addition, maleimides, γ-aryl-substituted deconjugated butenolides, chiral butenolides with adjacent quaternary and tertiary stereocenters, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMichael Addition, Vinylogous Michael Addition Cascade reaction, 5-benzylidene-2,2-dimethyl-1,3-dioxane-4,6-dione, diethyl (E)-2-((5-bromo-2-hydroxybenzylidene)amino)malonate, diethyl (3S,3aR,9bS)-8-bromo-4-oxo-3-phenyl-1,3a,4,9b-tetrahydrochromeno[4,3-b]pyrrole-2,2(3H)-dicarboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction Spirocyclization, 3-(2-methylallyl)cyclohex-2-en-1-one, (E)-1-methoxy-2-(2-nitrovinyl)benzene, (6S,10R,11R)-10-(2-methoxyphenyl)-8-methyl-11-nitrospiro[5.5]undec-7-en-2-one, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeSpirocyclization [3+3]-Annulation, 2-(1-Alkynyl)-2-alken-1-ones, 3-Aminobenzofurans, Polycyclic 1,4-Dihydropyridines, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative[3+3]-Annulation, Cyclization, Further Cyclizations Cascade reaction, 2-phenyl-N-(quinolin-8-yl)acrylamide, nitromethane, methyl (E)-3-iodoacrylate, methyl 2-((1R,2R,4R)-2-nitro-4-(quinolin-8-ylcarbamoyl)-1,2,3,4-tetrahydronaphthalen-1-yl)acetate, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCascade reaction Atropisomer Synthesis, 2-naphthalen-imidazoles, 1-(bromomethyl)-pentafluorobenzene, axially chiral imidazoles, (9S)-N-[(3,5-difluorophenyl)methyl]-6′,9-dihydroxy-cinchonanium bromide, Cupreidine DerivativeAtropisomer synthesis, Desymmetrization Vinylogous Michael Addition, 5-methylfuran-2(3H)-one, tert-butyl 2-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate, tert-butyl (R)-4-((R)-2-methyl-5-oxo-2,5-dihydrofuran-2-yl)-2-oxopyrrolidine-1-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]- N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeMichael Addition, Vinylogous Michael Addition Nazarov Cyclization, substituted (E)-hepta-4,6-diene-2,3-dione, substituted 5-hydroxy-4-methylenecyclopent-2-en-1-one, (3α,9S)-3,9-epoxy-10,11-dihydro-cinchonan-6′-ol, Dihydrocupreidine DerivativeCyclization, Further Cyclizations, Nazarov cyclization Decarboxylative Protonation, substituted 2-(ethoxycarbonyl)-4-oxopentanoic acid, substituted ethyl 4-oxopentanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeDecarboxylative Protonation, Protonation Atropisomer Synthesis, diethyl 2-(2-(benzyloxy)naphthalen-1-yl)-1-((tert-butoxycarbonyl)amino)-5-methyl-1H-pyrrole-3,4-dicarboxylate, methyl 2-(((tert-butoxycarbonyl)oxy)methyl)acrylate, 1,2-diaxial atropisomers, Dihydroquinidine BaseAtropisomer synthesis« Older EntriesNext Entries »
Vinylogous Michael Addition, maleimides, γ-aryl-substituted deconjugated butenolides, chiral butenolides with adjacent quaternary and tertiary stereocenters, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMichael Addition, Vinylogous Michael Addition
Cascade reaction, 5-benzylidene-2,2-dimethyl-1,3-dioxane-4,6-dione, diethyl (E)-2-((5-bromo-2-hydroxybenzylidene)amino)malonate, diethyl (3S,3aR,9bS)-8-bromo-4-oxo-3-phenyl-1,3a,4,9b-tetrahydrochromeno[4,3-b]pyrrole-2,2(3H)-dicarboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction
Spirocyclization, 3-(2-methylallyl)cyclohex-2-en-1-one, (E)-1-methoxy-2-(2-nitrovinyl)benzene, (6S,10R,11R)-10-(2-methoxyphenyl)-8-methyl-11-nitrospiro[5.5]undec-7-en-2-one, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeSpirocyclization
[3+3]-Annulation, 2-(1-Alkynyl)-2-alken-1-ones, 3-Aminobenzofurans, Polycyclic 1,4-Dihydropyridines, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative[3+3]-Annulation, Cyclization, Further Cyclizations
Cascade reaction, 2-phenyl-N-(quinolin-8-yl)acrylamide, nitromethane, methyl (E)-3-iodoacrylate, methyl 2-((1R,2R,4R)-2-nitro-4-(quinolin-8-ylcarbamoyl)-1,2,3,4-tetrahydronaphthalen-1-yl)acetate, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCascade reaction
Atropisomer Synthesis, 2-naphthalen-imidazoles, 1-(bromomethyl)-pentafluorobenzene, axially chiral imidazoles, (9S)-N-[(3,5-difluorophenyl)methyl]-6′,9-dihydroxy-cinchonanium bromide, Cupreidine DerivativeAtropisomer synthesis, Desymmetrization
Vinylogous Michael Addition, 5-methylfuran-2(3H)-one, tert-butyl 2-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate, tert-butyl (R)-4-((R)-2-methyl-5-oxo-2,5-dihydrofuran-2-yl)-2-oxopyrrolidine-1-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]- N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeMichael Addition, Vinylogous Michael Addition
Nazarov Cyclization, substituted (E)-hepta-4,6-diene-2,3-dione, substituted 5-hydroxy-4-methylenecyclopent-2-en-1-one, (3α,9S)-3,9-epoxy-10,11-dihydro-cinchonan-6′-ol, Dihydrocupreidine DerivativeCyclization, Further Cyclizations, Nazarov cyclization
Decarboxylative Protonation, substituted 2-(ethoxycarbonyl)-4-oxopentanoic acid, substituted ethyl 4-oxopentanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeDecarboxylative Protonation, Protonation
Atropisomer Synthesis, diethyl 2-(2-(benzyloxy)naphthalen-1-yl)-1-((tert-butoxycarbonyl)amino)-5-methyl-1H-pyrrole-3,4-dicarboxylate, methyl 2-(((tert-butoxycarbonyl)oxy)methyl)acrylate, 1,2-diaxial atropisomers, Dihydroquinidine BaseAtropisomer synthesis
